Effects of subcutaneous vs. oral nanoparticle-mediated insulin delivery on hemostasis disorders in type 1 diabetes: A rat model study

Autor: Nawel Kaddour, Farah Benyettou, Kawtar Moulai, Abdelouahab Mebarki, Katia Allal-Taouli, Rose Ghemrawi, Jamie Whelan, Hafida Merzouk, Ali Trabolsi, Nassima Amel Mokhtari-Soulimane

Publikováno v: Heliyon, Vol 10, Iss 9, Pp e30450- (2024)

Complications associated with Type 1 diabetes (T1D) have complex origins that revolve around chronic hyperglycemia; these complications involve hemostasis disorders, coagulopathies, and vascular damage. Our study aims to develop innovative approaches

Externí odkaz: https://doaj.org/article/230a5703294a4b6bb22858365dd43afc

Fluorescence turn on amine detection in a cationic covalent organic framework

Autor: Gobinda Das, Bikash Garai, Thirumurugan Prakasam, Farah Benyettou, Sabu Varghese, Sudhir Kumar Sharma, Felipe Gándara, Renu Pasricha, Maria Baias, Ramesh Jagannathan, Na’il Saleh, Mourad Elhabiri, Mark A. Olson, Ali Trabolsi

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Ionic covalent organic frameworks (iCOFs) are new examples of porous materials and show great potential for various applications. Here, the authors demonstrate functionalization of an iCOFs with suitable emission sites and application as chemosensor

Externí odkaz: https://doaj.org/article/27ec0687b97a47ad81f2788ae1a2a868

Covalent Organic Framework Embedded with Magnetic Nanoparticles for MRI and Chemo-Thermotherapy

Autor: Digambar Balaji Shinde, Renu Pasricha, Laurence Motte, Osama Abdullah, Ali Trabolsi, Anjana Ramdas Nair, Jamie Whelan, Kirsten C. Sadler, Farah Benyettou, Gobinda Das, Felipe Gándara, Yoann Lalatonne, Thirumurugan Prakasam, Seema Sharma, Ramesh Jagannathan, Hassan Traboulsi, Zhiping Lai

Publikováno v: Journal of the American Chemical Society. 142:18782-18794

Nanoscale imine-linked covalent organic frameworks (nCOFs) were first loaded with the anticancer drug Doxorubicin (Dox), coated with magnetic iron oxide nanoparticles (γ-Fe2O3 NPs), and stabilized with a shell of poly(l-lysine) cationic polymer (PLL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acfd74548dedac0c957b9da92bbdc0c
https://doi.org/10.1021/jacs.0c05381

Viologen–cucurbituril host/guest chemistry – redox control of dimerization versus inclusion

Autor: Ali Trabolsi, Parastoo Dalvand, Dinesh K. Shetty, Mourad Elhabiri, Farah Benyettou, Carlos Platas-Iglesias, Katia Nchimi Nono, Mark A. Olson, Zouhair Asfari

Publikováno v: RUC. Repositorio da Universidade da Coruña
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RSC Advances
RSC Advances, Royal Society of Chemistry, 2021, 11 (47), pp.29543-29554. ⟨10.1039/D1RA05488K⟩

International audience; Two calix[4]arene systems, C234+ and C244+, where 2 corresponds to the number of viologen units and 3-4 corresponds to the number of carbon atoms connecting the viologen units to the macrocyclic core, have been synthesized and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9a6cff5c8383d863f8fa74a7aa9e89
https://hdl.handle.net/2183/29412

Potent and selective in vitro and in vivo antiproliferative effects of metal–organic trefoil knots

Autor: Anjana Ramdas Nair, Ini Isabee Witzel, Farah Benyettou, Tina Skorjanc, Thirumurugan Prakasam, Kirsten C. Sadler, John Carl Olsen, Ali Trabolsi, Marwa Alhashimi

Publikováno v: Chemical Science. 10:5884-5892

A set of metal–organic trefoil knots (M-TKs) generated by metal-templated self-assembly of a simple pair of chelating ligands were well tolerated in vitro by non-cancer cells but were significantly more potent than cisplatin in both human cancer ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12c2502d899f59d3ed049438bd822cd4
https://doi.org/10.1039/c9sc01218d