A SIRT1-independent mechanism mediates protection against steroid-induced senescence by resveralogues in equine tenocytes.

Autor: Heidari, Neda¹ (AUTHOR) nedaheidari70@gmail.com, Faragher, Richard G. A.¹ (AUTHOR), Pattison, Graham² (AUTHOR), Dudhia, Jayesh³ (AUTHOR), Smith, Roger K. W.³ (AUTHOR)

Publikováno v: PLoS ONE. 8/22/2024, Vol. 19 Issue 8, p1-17. 17p.

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Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

Autor: Bikkul, Mehmet U, Faragher, Richard G A, Worthington, Gemma, Meinke, Peter, Kerr, Alastair R W, Sammy, Aakila, Riyahi, Kumars, Horton, Daniel, Schirmer, Eric C, Hubank, Michael, Kill, Ian R, Anderson, Rhona M, Slijepcevic, Predrag, Makarov, Evgeny, Bridger, Joanna M

Publikováno v: Bikkul, M U, Faragher, R G A, Worthington, G, Meinke, P, Kerr, A R W, Sammy, A, Riyahi, K, Horton, D, Schirmer, E C, Hubank, M, Kill, I R, Anderson, R M, Slijepcevic, P, Makarov, E & Bridger, J M 2019, ' Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform ', Genes, Chromosomes and Cancer, vol. 58, no. 6, pp. 341-356 . https://doi.org/10.1002/gcc.22711

Immortalizing primary cells with human telomerase reverse transcriptase (hTERT) has been common practice to enable primary cells to be of extended use in the laboratory because they avoid replicative senescence. Studying exogenously expressed hTERT i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0dfad3322cc4b711bb6a30657b85d984
https://bura.brunel.ac.uk/handle/2438/17178

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