Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Faraaz N.K. Yusufi"'
Autor:
Nandita Vishwanathan, Nitya M. Jacob, Hsu Yuan Fu, Wei Shou Hu, Huong Le, Dong-Yup Lee, Andrew Yongky, Kathryn C. Johnson, Faraaz N.K. Yusufi
Publikováno v:
Biotechnology and Bioengineering. 112:965-976
Transcriptomics is increasingly being used on Chinese hamster ovary (CHO) cells to unveil physiological insights related to their performance during production processes. The rich transcriptome data can be exploited to provide impetus for systems inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f5a63df4c639a86bec88a1069be52f6
https://doi.org/10.1002/bit.25513
https://doi.org/10.1002/bit.25513
Publikováno v:
Journal of Biotechnology. 167:326-333
The human interferon-gamma (IFN-γ) is a potential drug candidate for treating various diseases due to its immunomodulatory properties. The efficient production of this protein can be achieved through a popular industrial host, Chinese hamster ovary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbfd1e5fe82f4ce02138452e27584bc
https://doi.org/10.1016/j.jbiotec.2013.07.011
https://doi.org/10.1016/j.jbiotec.2013.07.011
Publikováno v:
Drug Development Research. 72:121-129
Mycobacterium tuberculosis is the deadly pathogen responsible for causing tuberculosis in humans, continuing to infect and kill millions of people globally. Despite the availability of a number of anti-tuberculosis drugs and advances in high-throughp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d30d1a0aa2c6737f532de034f22e3b4
https://doi.org/10.1002/ddr.20408
https://doi.org/10.1002/ddr.20408
Autor:
Satty G. Reddy, Ying Swan Ho, William P. K. Chong, Chew-Kiat Heng, Miranda G.S. Yap, Niki S.C. Wong, Dong-Yup Lee, Faraaz N.K. Yusufi
Publikováno v:
Journal of Biotechnology. 147:116-121
We have established a liquid chromatography-mass spectrometry based metabolomics platform to identify extracellular metabolites in the medium of recombinant Chinese hamster ovary (CHO) fed-batch reactor cultures. Amongst the extracellular metabolites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24184eafcbb2e0e45b68cb74003ca06
https://doi.org/10.1016/j.jbiotec.2010.03.018
https://doi.org/10.1016/j.jbiotec.2010.03.018
Autor:
Satty G. Reddy, Lin Tang Goh, Chew-Kiat Heng, Ying Swan Ho, William P. K. Chong, Miranda G.S. Yap, Niki S.C. Wong, Faraaz N.K. Yusufi, Dong-Yup Lee
Publikováno v:
Rapid Communications in Mass Spectrometry. 23:3763-3771
A metabolomics-based approach was used to time profile extracellular metabolites in duplicate fed-batch bioreactor cultures of recombinant Chinese Hamster Ovary (CHO) cells producing monoclonal IgG antibody. Culture medium was collected and analysed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b16b5ab8504b277c4719f33845b4d028
https://doi.org/10.1002/rcm.4328
https://doi.org/10.1002/rcm.4328
Autor:
Faraaz N.K. Yusufi, Miranda Yap, Wei Shou Hu, Peter Morin Nissom, Song Hui Chuah, Anne Kantardjieff, Nitya M. Jacob, Bhanu Chandra Mulukutla
Publikováno v:
Biotechnology Advances. 27:1028-1035
Chinese hamster ovary (CHO) cells are widely used in recombinant protein production, yet despite their importance in bioprocessing, few genomic resources have been developed for this cell line. Over the past several years, we have made considerable p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbff6aac5468b4641aba4c6c3a3de1c4
https://doi.org/10.1016/j.biotechadv.2009.05.023
https://doi.org/10.1016/j.biotechadv.2009.05.023
Publikováno v:
Briefings in Bioinformatics. 10:65-74
Mathematical modelling and computational analysis play an essential role in improving our capability to elucidate the functions and characteristics of complex biological systems such as metabolic, regulatory and cell signalling pathways. The modellin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe4f06198beeedd6126e52da572ab78
https://doi.org/10.1093/bib/bbn039
https://doi.org/10.1093/bib/bbn039
Autor:
Corrine Wan, Hock Chuan Yeo, Sze Wai Ng, Chung Ping Chow, Faraaz N.K. Yusufi, Ai Ping Hiu, Ju Xin Chin, Yuansheng Yang, Xiaoan Ruan, Ken Wing Kin Sung, Bernard Loo, Miranda Gek Sim Yap, Gavin Teo, Say Kong Ng, Wei Shou Hu, Pramila N. Ariyaratne, Gao Song, Dong-Yup Lee, Muriel Bardor, Ying Swan Ho, Shuwen Chen, Tessa Rui Min Tan, Niranjan Nagarajan, Hsueh Lee Lim, Meiyappan Lakshmanan
Publikováno v:
Cell Systems
Cell Systems, Elsevier, 2017, 4 (5), pp.530-542.e6. ⟨10.1016/j.cels.2017.04.009⟩
Cell Systems, Elsevier, 2017, 4 (5), pp.530-542.e6. ⟨10.1016/j.cels.2017.04.009⟩
Effective development of host cells for therapeutic protein production is hampered by the poor characterization of cellular transfection. Here, we employed a multi-omics-based systems biotechnology approach to elucidate the genotypic and phenotypic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f78e4ba211751102ea86ce76d777c9f
https://doi.org/10.1016/j.cels.2017.04.009
https://doi.org/10.1016/j.cels.2017.04.009
Publikováno v:
Microbial Biotechnology: Principles and Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f84e34cfab59b23100b6507d5c8a8e
https://doi.org/10.1142/9789814366830_0003
https://doi.org/10.1142/9789814366830_0003
Autor:
Chew-Kiat Heng, Faraaz N.K. Yusufi, Miranda G.S. Yap, Satty G. Reddy, Dong-Yup Lee, Ying Swan Ho, William P. K. Chong, Niki S.C. Wong
Publikováno v:
Journal of biotechnology. 151(2)
A liquid chromatography–mass spectrometry (LC–MS) based metabolomics platform was previously established to identify and profile extracellular metabolites in culture media of mammalian cells. This presented an opportunity to isolate novel apoptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4908d5a1269f35d9b7c8d695792ec00
https://pubmed.ncbi.nlm.nih.gov/21167884
https://pubmed.ncbi.nlm.nih.gov/21167884