Hepatic triglyceride content is intricately associated with numerous metabolites and biochemical pathways.

Autor: Faquih, Tariq O.¹ (AUTHOR), van Klinken, Jan Bert^2,3,4 (AUTHOR), Li‐Gao, Ruifang^1,5 (AUTHOR), Noordam, Raymond⁶ (AUTHOR), van Heemst, Diana⁶ (AUTHOR), Boone, Sebastiaan¹ (AUTHOR), Sheridan, Patricia A.⁵ (AUTHOR), Michelotti, Gregory⁵ (AUTHOR), Lamb, Hildo⁷ (AUTHOR), de Mutsert, Renée¹ (AUTHOR), Rosendaal, Frits R.¹ (AUTHOR), van Hylckama Vlieg, Astrid¹ (AUTHOR), van Dijk, Ko Willems^2,8,9 (AUTHOR), Mook‐Kanamori, Dennis O.^1,10 (AUTHOR) d.o.mook@lumc.nl

Publikováno v: Liver International. Jul2023, Vol. 43 Issue 7, p1458-1472. 15p. 3 Diagrams, 2 Charts, 1 Graph.

Idiopathic Atrial Flutter Associated with Dilated Cardiomyopathy in a Preterm Newborn: A Case Report

Autor: Nitin Unde, Mahmoud ElHalik, Arif Faquih

Publikováno v: Dubai Medical Journal, Pp 1-4 (2021)

Background: Arrhythmias in neonates are uncommon and usually affect newborns with a normal heart or associated with structural heart disease. Meanwhile, one uncommon type of supraventricular arrhythmias is atrial flutter (AF), which is reentry mechan

Externí odkaz: https://doaj.org/article/7b2c2225ba1e48cfac17f30f675ee5e1

The lipid profile for the prediction of prednisolone treatment response in patients with inflammatory hand osteoarthritis: The HOPE study

Autor: Marieke Loef, Tariq O. Faquih, Johannes H. von Hegedus, Mohan Ghorasaini, Andreea Ioan-Facsinay, Féline P.B. Kroon, Martin Giera, Margreet Kloppenburg

Publikováno v: Osteoarthritis and Cartilage Open, Vol 3, Iss 4, Pp 100167- (2021)

Objective: To explore the use of lipidomics for prediction of prednisolone treatment response in patients with inflammatory hand osteoarthritis. Design: The Hand Osteoarthritis Prednisolone Efficacy (HOPE) study included patients (n ​= ​92) with

Externí odkaz: https://doaj.org/article/46924a1e30a54f68aad8d3ef25ced081

Agreement of aptamer proteomics with standard methods for measuring venous thrombosis biomarkers

Autor: Tariq Faquih, Dennis O. Mook‐Kanamori, Frits R. Rosendaal, Trevor Baglin, Ko Willems van Dijk, Astrid vanHylckama Vlieg

Publikováno v: Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 4, Pp n/a-n/a (2021)

Abstract Background Venous thromboembolism (VTE) is a complex disease with an incidence rate of about 1 in 1000 per year. Despite the availability of validated biomarkers for VTE, unprovoked events account for 50% of first events. Therefore, emerging

Externí odkaz: https://doaj.org/article/83b83b04aef3441c9c80f51eeee98771

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

Autor: Shrine, Nick, Izquierdo, Abril G, Chen, Jing, Packer, Richard, Hall, Robert J, Guyatt, Anna L, Batini, Chiara, Thompson, Rebecca J, Pavuluri, Chandan, Malik, Vidhi, Hobbs, Brian D, Moll, Matthew, Kim, Wonji, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A, John, Catherine, Coley, Kayesha, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Millwood, Iona Y, Chen, Zhengming, Li, Liming, China Kadoorie Biobank Collaborative Group, Wijnant, Sara RA, Lahousse, Lies, Brusselle, Guy, Uitterlinden, Andre G, Manichaikul, Ani, Oelsner, Elizabeth C, Rich, Stephen S, Barr, R Graham, Kerr, Shona M, Vitart, Veronique, Brown, Michael R, Wielscher, Matthias, Imboden, Medea, Jeong, Ayoung, Bartz, Traci M, Gharib, Sina A, Flexeder, Claudia, Karrasch, Stefan, Gieger, Christian, Peters, Annette, Stubbe, Beate, Hu, Xiaowei, Ortega, Victor E, Meyers, Deborah A, Bleecker, Eugene R, Gabriel, Stacey B, Gupta, Namrata, Smith, Albert Vernon, Luan, Jian'an, Zhao, Jing-Hua, Hansen, Ailin F, Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H, Campbell, Archie, Sofer, Tamar, Lee, Jiwon, Daviglus, Martha L, Yu, Bing, Lim, Elise, Xu, Hanfei, O'Connor, George T, Thareja, Gaurav, Albagha, Omar ME, Qatar Genome Program Research (QGPR) Consortium, Suhre, Karsten, Granell, Raquel, Faquih, Tariq O, Hiemstra, Pieter S, Slats, Annelies M, Mullin, Benjamin H, Hui, Jennie, James, Alan, Beilby, John, Patasova, Karina, Hysi, Pirro, Koskela, Jukka T, Wyss, Annah B, Jin, Jianping, Sikdar, Sinjini, Lee, Mikyeong, May-Wilson, Sebastian, Pirastu, Nicola, Kentistou, Katherine A, Joshi, Peter K, Timmers, Paul RHJ, Williams, Alexander T, Free, Robert C, Wang, Xueyang, Morrison, John L, Gilliland, Frank D, Chen, Zhanghua, Wang, Carol A, Foong, Rachel E, Harris, Sarah E, Taylor, Adele, Redmond, Paul, Cook, James P, Mahajan, Anubha, Lind, Lars, Palviainen, Teemu, Lehtimäki, Terho, Raitakari, Olli T, Kaprio, Jaakko, Rantanen, Taina, Pietiläinen, Kirsi H, Cox, Simon R, Pennell, Craig E, Hall, Graham L, Gauderman, W James, Brightling, Chris, Wilson, James F, Vasankari, Tuula, Laitinen, Tarja, Salomaa, Veikko, Mook-Kanamori, Dennis O, Timpson, Nicholas J, Zeggini, Eleftheria, Dupuis, Josée, Hayward, Caroline, Brumpton, Ben, Langenberg, Claudia, Weiss, Stefan, Homuth, Georg, Schmidt, Carsten Oliver, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C, Polasek, Ozren, Rudan, Igor, Lee, Joo-Hyeon, Sayers, Ian, Rawlins, Emma L, Dudbridge, Frank, Silverman, Edwin K, Strachan, David P, Walters, Robin G, Morris, Andrew P, London, Stephanie J, Cho, Michael H, Wain, Louise V, Hall, Ian P, Tobin, Martin D

Publikováno v: Nature Genetics
Cox, S R 2023, ' Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk ', Nature Genetics, vol. 55, no. 3, pp. 410-422 . https://doi.org/10.1038/s41588-023-01314-0
Nature Genetics, 55(3), 410-422. Nature Publishing Group

Funder: British Lung Foundation
Funder: National Institute for Health Research (NIHR)
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1590d1d51b8c0fa4d03e7e609ef177f2
https://www.repository.cam.ac.uk/handle/1810/347786