Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Faqian Li"'
Autor:
Wenya Ma, Yanan Tian, Leping Shi, Jing Liang, Qimeng Ouyang, Jianglong Li, Hongyang Chen, Hongyue Sun, Haoyu Ji, Xu Liu, Wei Huang, Xinlu Gao, Xiaoyan Jin, Xiuxiu Wang, Yining Liu, Yang Yu, Xiaofei Guo, Ye Tian, Fan Yang, Faqian Li, Ning Wang, Benzhi Cai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Translational control is crucial for protein production in various biological contexts. Here, we use Ribo-seq and RNA-seq to show that genes related to oxidative phosphorylation are translationally downregulated during heart regeneration. We
Externí odkaz:
https://doaj.org/article/42fb7334384e46d5a6c07d984296926e
Autor:
Qianjin Guo, Zi-Ming Cheng, Hector Gonzalez-Cantú, Matthew Rotondi, Gabriela Huelgas-Morales, Purushoth Ethiraj, Zhijun Qiu, Jonathan Lefkowitz, Wan Song, Bethany N. Landry, Hector Lopez, Cynthia M. Estrada-Zuniga, Shivi Goyal, Mohammad Aasif Khan, Timothy J. Walker, Exing Wang, Faqian Li, Yanli Ding, Lois M. Mulligan, Ricardo C.T. Aguiar, Patricia L.M. Dahia
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113070- (2023)
Summary: The TMEM127 gene encodes a transmembrane protein of poorly known function that is mutated in pheochromocytomas, neural crest-derived tumors of adrenomedullary cells. Here, we report that, at single-nucleus resolution, TMEM127-mutant tumors s
Externí odkaz:
https://doaj.org/article/74efd737d1554c5e84e35c4daa5fe892
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-9 (2021)
Abstract Background Percutaneous needle biopsy of renal masses has been increasingly utilized to aid the diagnosis and guide management. It is generally considered as a safe procedure. However, tumor seeding along the needle tract, one of the complic
Externí odkaz:
https://doaj.org/article/c43b233475c4460b829e6d8a831456b7
Autor:
Penglong Wu, Yifan Li, Mingqi Cai, Bo Ye, Bingchuan Geng, Faqian Li, Hua Zhu, Jinbao Liu, Xuejun Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinase known to play essential roles in the nervous tissue. Myocardial upregulation of UCHL1 was observed in human dilated cardiomyopathy and several animal models of heart disease, but th
Externí odkaz:
https://doaj.org/article/642628ef141b4565a88ddc14c9631df4
Publikováno v:
Case Reports in Nephrology, Vol 2020 (2020)
Recent studies suggest that galactose-deficient IgA1 (Gd-IgA1) plays a role in the pathogenesis of primary IgA nephropathy (IgAN) and Henoch–Schönlein purpura nephritis (HSPN). Furthermore, immunostaining of KM55, an antibody that identifies Gd-Ig
Externí odkaz:
https://doaj.org/article/1e4366eab3064ef58eb2ba0655376723
Publikováno v:
Case Reports in Hematology, Vol 2019 (2019)
Pure white cell aplasia (PWCA) is a rare manifestation of thymoma. It is characterized by agranulocytosis with absent myeloid precursors in the bone marrow and normal hematopoiesis for other cell lines. Here we describe a 65-year-old female patient w
Externí odkaz:
https://doaj.org/article/d1ea493d0efe483c8ccfa1c9d344f80b
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67793 (2013)
The COP9 signalosome (CSN), an evolutionally highly conserved protein complex composed of 8 unique subunits (CSN1 through CSN8) in higher eukaryotes, is purported to modulate protein degradation mediated by the ubiquitin-proteasome system (UPS) but t
Externí odkaz:
https://doaj.org/article/dcc1193e65064711991839c4aeb8add2
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32738 (2012)
Na(V)1.5 is a cardiac voltage-gated Na(+) channel αsubunit and is encoded by the SCN5a gene. The activity of this channel determines cardiac depolarization and electrical conduction. Channel defects, including mutations and decrease of channel prote
Externí odkaz:
https://doaj.org/article/e9958766a6314c528e96320b4e2b320b
Autor:
Mingqi Cai, Bo Pan, Peng Xiao, Bouska, Mark, Lewno, Megan T., Yu Xing, Erliang Zeng, Huiyun Liang, Faqian Li, Xiang Gao, Xuejun Wang
Publikováno v:
Circulation; 10/15/2024, Vol. 150 Issue 16, p1302-1305, 4p
Autor:
Hong, Guo, Jibin, Guan, Xian, Wu, Yushuang, Wei, Jiaqi, Zhao, Yan, Zhou, Faqian, Li, Hong-Bo, Pang
Publikováno v:
Molecular Therapy. 31:875-889
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are life-threatening conditions with excessive inflammation in the lung. Glucocorticoids had been widely used for ALI/ARDS, but their clinical benefit remains unclear. Here, we tackle