Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Faping Li"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic Kidney Disease (CKD) stands as a substantial challenge within the global health landscape. The elevated metabolic demands essential for sustaining normal kidney function have propelled an increasing interest in unraveling the intrica
Externí odkaz:
https://doaj.org/article/0c7f26c55c7c485cab25103e3a3a842a
Autor:
Yunkuo Li, Yujie Pan, Xiangzhe Yang, Yuxiong Wang, Bin Liu, Yanghe Zhang, Xin Gao, Yishu Wang, Honglan Zhou, Faping Li
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Non-muscle myosin heavy chain IIA (MYH9), a member of the non-muscle myosin II (NM II) family, is widely expressed in cells. The interaction of MYH9 with actin in the cytoplasm can hydrolyze ATP, completing the conversion of chemical energy
Externí odkaz:
https://doaj.org/article/ae930ab11524406788385badbabc0255
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Neuroendocrine tumors (NETs) are a rare type of neoplasm that originate from neuroendocrine cells and peptide neurons. Primary renal well-differentiated NETs are extremely rare, and only a few cases have been reported worldwide. In this study, we pre
Externí odkaz:
https://doaj.org/article/3bfc0a0be15446ae947d968529237175
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundKidney injuries often carry a grim prognosis, marked by fibrosis development, renal function loss, and macrophage involvement. Despite extensive research on macrophage polarization and its effects on other cells, like fibroblasts, limited a
Externí odkaz:
https://doaj.org/article/80aedc369e304e96a3c6b6a79b69f4fc
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundDespite the potential demonstrated by targeted plasma metabolite modulators in halting the progression of chronic kidney disease (CKD), a lingering uncertainty persists concerning the causal relationship between distinct plasma metabolites
Externí odkaz:
https://doaj.org/article/5200c45e225947f0858432d4b8394fe7
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Purpose: On 12 April 2019, erdafitinib gained the first FDA approval as the second-line treatment for adult patients with locally advanced or metastatic urothelial cancer following progression during or after at least one previous line of platinum-ba
Externí odkaz:
https://doaj.org/article/82b83ae639bf4f40bb73d0693f6246e0
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors originating from chromaffin cells, holding significant clinical importance due to their capacity for excessive catecholamine secretion and associated cardiovascular complicat
Externí odkaz:
https://doaj.org/article/3610e2be4d06404abdc4ae317f0d1b83
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 165, Iss , Pp 115229- (2023)
Renal ischemia-reperfusion injury (RIRI) is a complex disorder characterized by both intrinsic damage to renal tubular epithelial cells and extrinsic inflammation mediated by cytokines and immune cells. Unfortunately, there is no cure for this devast
Externí odkaz:
https://doaj.org/article/5054b099bb554791827f78acd795ffd4
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Clear cell renal cell carcinoma (ccRCC) is associated with unfavorable clinical outcomes. To identify viable therapeutic targets, a comprehensive understanding of intratumoral heterogeneity is crucial. In this study, we conducted bioinf
Externí odkaz:
https://doaj.org/article/fe72ecd99439421487c7f932530b1e10
Autor:
Yunkuo Li, Shouwang Wu, Xiaodong Zhao, Shiming Hao, Faping Li, Yuxiong Wang, Bin Liu, Difei Zhang, Yishu Wang, Honglan Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Lipid metabolism reprogramming is an important hallmark of tumor progression. Cancer cells require high levels of lipid synthesis and uptake not only to support their continued replication, invasion, metastasis, and survival but also to participate i
Externí odkaz:
https://doaj.org/article/f3625f581ec042d4a147db92059bef14