Zobrazeno 1 - 10
of 295
pro vyhledávání: '"Fanyin Meng"'
Autor:
Phillip L. Lewis, Jimmy Su, Ming Yan, Fanyin Meng, Shannon S. Glaser, Gianfranco D. Alpini, Richard M. Green, Beatriz Sosa-Pineda, Ramille N. Shah
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/83f036818b7e405ab8c3fd6ebd5c1192
Autor:
Bowen Li, Hui Wang, Yudian Zhang, Ying Liu, Tiejun Zhou, Bingru Zhou, Ying Zhang, Rong Chen, Juan Xing, Longfei He, Jennifer Mata Salinas, Sachiko Koyama, Fanyin Meng, Ying Wan
Publikováno v:
Cells, Vol 11, Iss 23, p 3783 (2022)
Liver fibrosis is a complicated process that involves different cell types and pathological factors. The excessive accumulation of extracellular matrix (ECM) and the formation of fibrotic scar disrupt the tissue homeostasis of the liver, eventually l
Externí odkaz:
https://doaj.org/article/bd329a714f8f4f61899e1c275cb2919e
Autor:
Tianhao Zhou, Konstantina Kyritsi, Nan Wu, Heather Francis, Zhihong Yang, Lixian Chen, April O'Brien, Lindsey Kennedy, Ludovica Ceci, Vik Meadows, Praveen Kusumanchi, Chaodong Wu, Leonardo Baiocchi, Nicholas J. Skill, Romil Saxena, Amelia Sybenga, Linglin Xie, Suthat Liangpunsakul, Fanyin Meng, Gianfranco Alpini, Shannon Glaser
Publikováno v:
EBioMedicine, Vol 48, Iss , Pp 130-142 (2019)
Background: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is an intermediate filament protein that has been found in various types of mesenchymal cells. The aim of this study is to ev
Externí odkaz:
https://doaj.org/article/606ab22e62a04d15a60b567e6cc3dc44
Publikováno v:
Liver Research, Vol 3, Iss 1, Pp 40-45 (2019)
Cholangiopathies are caused by bile duct damage or inflammation followed by cholestasis leading to liver fibrosis. Bile duct epithelial cells, cholangiocytes, are a primary target for cholangiopathies. Ductular reaction is often observed in cholangio
Externí odkaz:
https://doaj.org/article/6a4e1de1d8504ea1889e8e738aedac36
Autor:
Phillip L. Lewis, Jimmy Su, Ming Yan, Fanyin Meng, Shannon S. Glaser, Gianfranco D. Alpini, Richard M. Green, Beatriz Sosa-Pineda, Ramille N. Shah
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract The biliary tree is an essential component of transplantable human liver tissue. Despite recent advances in liver tissue engineering, attempts at re-creating the intrahepatic biliary tree have not progressed significantly. The finer branches
Externí odkaz:
https://doaj.org/article/456249077e1a4cbbbbc9bd397904fcf4
Autor:
Xin Guo, Chang Shu, Honggui Li, Ya Pei, Shih-Lung Woo, Juan Zheng, Mengyang Liu, Hang Xu, Rachel Botchlett, Ting Guo, Yuli Cai, Xinsheng Gao, Jing Zhou, Lu Chen, Qifu Li, Xiaoqiu Xiao, Linglin Xie, Ke K. Zhang, Jun-Yuan Ji, Yuqing Huo, Fanyin Meng, Gianfranco Alpini, Pingwei Li, Chaodong Wu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Endogenous cyclic GMP-AMP (cGAMP) binds and activates STING to induce type I interferons. However, whether cGAMP plays any roles in regulating metabolic homeostasis remains unknown. Here we show that exogenous cGAMP ameliorates obesity-assoc
Externí odkaz:
https://doaj.org/article/0eb94b4ac1234b1abef97562d680489e
Publikováno v:
Liver Research, Vol 1, Iss 1, Pp 34-41 (2017)
Cholangiopathies are a group of rare, devastating diseases that arise from damaged cholangiocytes, the cells that line the intra- and extra-hepatic bile ducts of the biliary epithelium. Cholangiopathies result in significant morbidity and mortality a
Externí odkaz:
https://doaj.org/article/88374190d6404d45a9696bca4bcd7aa1
Autor:
Keisaku Sato, Heather Francis, Tianhao Zhou, Fanyin Meng, Lindsey Kennedy, Burcin Ekser, Leonardo Baiocchi, Paolo Onori, Romina Mancinelli, Eugenio Gaudio, Antonio Franchitto, Shannon Glaser, Gianfranco Alpini
Publikováno v:
Cells, Vol 9, Iss 2, p 436 (2020)
Cholangiocarcinoma (CCA) is a highly aggressive malignancy that emerges from the biliary tree. There are three major classes of CCA—intrahepatic, hilar (perihilar), or distal (extrahepatic)—according to the location of tumor development. Although
Externí odkaz:
https://doaj.org/article/044697cca99d49989acc16b2d16b7622
Autor:
Luca Maroni, Bai Haibo, Debolina Ray, Tianhao Zhou, Ying Wan, Fanyin Meng, Marco Marzioni, Gianfranco Alpini
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 4, Pp 368-380 (2015)
Cholangiocytes are the epithelial cells that line the bile ducts. Along the biliary tree, two different kinds of cholangiocytes exist: small and large cholangiocytes. Each type has important differences in their biological role in physiologic and pat
Externí odkaz:
https://doaj.org/article/4af1d33c68d9479ba65cce4c5b8d4eb3
Autor:
Elise Slevin, Sachiko Koyama, Kelly Harrison, Ying Wan, James E. Klaunig, Chaodong Wu, Ashok K. Shetty, Fanyin Meng
Publikováno v:
Journal of Cellular and Molecular Medicine. 27:891-905