Phenethyl Esters and Amide of Ferulic Acid, Hydroferulic Acid, Homovanillic Acid, and Vanillic Acid: Synthesis, Free Radicals Scavenging Activity, and Molecular Modeling as Potential Cholinesterases Inhibitors

Autor: Ayyoub Selka, Fanta J. Ndongou Moutombi, Marc Cormier, Mohamed Touaibia

Publikováno v: Molbank, Vol 2020, Iss 3, p M1151 (2020)

As ferulic acid was reported to be involved in novel potential mechanisms associated with Alzheimer’s disease (AD) therapy, five closely related phenethyl esters and amide of this natural product were synthesized and screened for their free radical

Externí odkaz: https://doaj.org/article/87c3293a6ca248fc8c9093486119a8f8

New Zileuton-Hydroxycinnamic Acid Hybrids: Synthesis and Structure-Activity Relationship towards 5-Lipoxygenase Inhibition

Autor: Audrey Isabel Chiasson, Samuel Robichaud, Fanta J. Ndongou Moutombi, Mathieu P. A. Hébert, Maroua Mbarik, Marc E. Surette, Mohamed Touaibia

Publikováno v: Molecules, Vol 25, Iss 20, p 4686 (2020)

A novel series of zileuton-hydroxycinnamic acid hybrids were synthesized and screened as 5-lipoxygenase (5-LO) inhibitors in stimulated HEK293 cells and polymorphonuclear leukocytes (PMNL). Zileuton’s (1) benzo[b]thiophene and hydroxyurea subunits

Externí odkaz: https://doaj.org/article/a97523b9f7f04864b0267c9d81daee1c

Hydroxycinnamic Acids and Their Related Synthetic Analogs: An Update of Pharmacological Activities

Autor: Jacques Jean-François, Fanta J. Ndongou Moutombi, Ayyoub Selka, Mohamed Touaibia

Publikováno v: Mini reviews in medicinal chemistry. 22(11)

The hydroxycinnamic acid scaffold is extremely versatile with various biological activities. This review will highlight the progress of the biological activities of hydroxycinnamic acids and their related synthetic analogs, including recently reporte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d3c46c254a526cd7f04d09ccc3b357
https://pubmed.ncbi.nlm.nih.gov/34784863

Partial and Total Solvent-Free Limonene’s Hydrogenation: Metals, Supports, Pressure, and Water Effects

Autor: Olivier Clarisse, Farid Chemat, Mohamed Touaibia, Fanta J. Ndongou Moutombi, Anne-Sylvie Fabiano-Tixier

Publikováno v: Journal of Chemistry, Vol 2020 (2020)
Journal of Chemistry
Journal of Chemistry, Hindawi Publishing Corporation, 2020, 2020, pp.1-11. ⟨10.1155/2020/5946345⟩

Bio-based solvents menthene and menthane were obtained through limonene’s partial and total hydrogenation under various catalytic conditions. Heterogeneous catalysts based on different active metals and supports (carbon, alumina, and silica) were s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5afdcced49c192bd1e693a71398f0a3
https://doaj.org/article/e0ee83fe15924e46a69918faef7551e8

Phenethyl Esters and Amide of Ferulic Acid, Hydroferulic Acid, Homovanillic Acid, and Vanillic Acid: Synthesis, Free Radicals Scavenging Activity, and Molecular Modeling as Potential Cholinesterases Inhibitors

Autor: Mohamed Touaibia, Fanta J. Ndongou Moutombi, Marc Cormier, Ayyoub Selka

Publikováno v: Molbank, Vol 2020, Iss M1151, p M1151 (2020)

As ferulic acid was reported to be involved in novel potential mechanisms associated with Alzheimer’s disease (AD) therapy, five closely related phenethyl esters and amide of this natural product were synthesized and screened for their free radical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f4acbf49aec7a9348a4e0e43f1d5a
https://doi.org/10.3390/m1151