Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fanny Wunder"'
Autor:
Vladimir Lazar, Eric Raymond, Shai Magidi, Catherine Bresson, Fanny Wunder, Ioana Berindan-Neagoe, Annemilaï Tijeras-Rabaland, Jacques Raynaud, Amir Onn, Michel Ducreux, Gerald Batist, Ulrik Lassen, Fin Cilius Nielsen, Richard L. Schilsky, Eitan Rubin, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Dysregulated pathways in cancer may be hub addicted. Identifying these dysregulated networks for targeting might lead to novel therapeutic options. Objective: Considering the hypothesis that central hubs are associated with increased leth
Externí odkaz:
https://doaj.org/article/da12cb09d31d4454bd2113b0c027167a
Autor:
Benjamin Solomon, Ana Callejo, Jair Bar, Guy Berchem, Lyudmila Bazhenova, Pierre Saintigny, Fanny Wunder, Jacques Raynaud, Nicolas Girard, J. Jack Lee, Raed Sulaiman, Bruce Prouse, Catherine Bresson, Hila Ventura, Shai Magidi, Eitan Rubin, Brandon Young, Amir Onn, Brian Leyland‐Jones, Richard L. Schilsky, Vladimir Lazar, Enriqueta Felip, Razelle Kurzrock
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2790-2800 (2022)
Abstract Background The Worldwide Innovative Network (WIN) Consortium has developed the Simplified Interventional Mapping System (SIMS) to better define the cancer molecular milieu based on genomics/transcriptomics from tumor and analogous normal tis
Externí odkaz:
https://doaj.org/article/9a1795592c8e42cab3df58cfe6f8ac80
Autor:
Vladimir Lazar, Baolin Zhang, Shai Magidi, Christophe Le Tourneau, Eric Raymond, Michel Ducreux, Catherine Bresson, Jacques Raynaud, Fanny Wunder, Amir Onn, Enriqueta Felip, Josep Tabernero, Gerald Batist, Razelle Kurzrock, Eitan Rubin, Richard L. Schilsky
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. Objective: Integrating t
Externí odkaz:
https://doaj.org/article/59159a57b2d143e3be0bcdbaf9afc021
Autor:
Vladimir Lazar, Jacques Raynaud, Shai Magidi, Catherine Bresson, Jean-François Martini, Susan Galbraith, Fanny Wunder, Amir Onn, Gerald Batist, Nicolas Girard, Ulrik Lassen, C. S. Pramesh, Amal Al-Omari, Sadakatsu Ikeda, Guy Berchem, Jean-Yves Blay, Benjamin Solomon, Enriqueta Felip, Josep Tabernero, Eitan Rubin, Thierry Philip, Angel Porgador, Ioana Berindan-Neagoe, Richard L. Schilsky, Razelle Kurzrock
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Background: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explored transcriptomic expression of angiotensin-converting enzyme 2 ( ACE2 , the SARS-CoV-2 receptor) and o
Externí odkaz:
https://doaj.org/article/cacbf20affbf406896e87fc22d539ae7
Autor:
Vladimir Lazar, Shai Magidi, Nicolas Girard, Alexia Savignoni, Jean-François Martini, Giorgio Massimini, Catherine Bresson, Raanan Berger, Amir Onn, Jacques Raynaud, Fanny Wunder, Ioana Berindan-Neagoe, Marina Sekacheva, Irene Braña, Josep Tabernero, Enriqueta Felip, Angel Porgador, Claudia Kleinman, Gerald Batist, Benjamin Solomon, Apostolia Maria Tsimberidou, Jean-Charles Soria, Eitan Rubin, Razelle Kurzrock, Richard L. Schilsky
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract The expanding targeted therapy landscape requires combinatorial biomarkers for patient stratification and treatment selection. This requires simultaneous exploration of multiple genes of relevant networks to account for the complexity of mec
Externí odkaz:
https://doaj.org/article/03d1a19c53bf406b8f14275e04c89c95
Autor:
Vladimir Lazar, Jacques Raynaud, Shai Magidi, Catherine Bresson, Jean-François Martini, Susan Galbraith, Fanny Wunder, Amir Onn, Gerald Batist, Nicolas Girard, Ulrik Lassen, C. S. Pramesh, Amal Al-Omari, Sadakatsu Ikeda, Guy Berchem, Jean-Yves Blay, Benjamin Solomon, Enriqueta Felip, Josep Tabernero, Eitan Rubin, Thierry Philip, Angel Porgador, Ioana Berindan-Neagoe, Richard L. Schilsky, Razelle Kurzrock
Publikováno v:
Scientia
Lazar, V, Raynaud, J, Magidi, S, Bresson, C, Martini, J F, Galbraith, S, Wunder, F, Onn, A, Batist, G, Girard, N, Lassen, U, Pramesh, C S, Al-Omari, A, Ikeda, S, Berchem, G, Blay, J Y, Solomon, B, Felip, E, Tabernero, J, Rubin, E, Philip, T, Porgador, A, Berindan-Neagoe, I, Schilsky, R L & Kurzrock, R 2022, ' Comorbidity between lung cancer and COVID-19 pneumonia : role of immunoregulatory gene transcripts in high ACE2-expressing normal lung ', Therapeutic Advances in Medical Oncology, vol. 14, pp. 1-15 . https://doi.org/10.1177/17588359221133893
Lazar, V, Raynaud, J, Magidi, S, Bresson, C, Martini, J F, Galbraith, S, Wunder, F, Onn, A, Batist, G, Girard, N, Lassen, U, Pramesh, C S, Al-Omari, A, Ikeda, S, Berchem, G, Blay, J Y, Solomon, B, Felip, E, Tabernero, J, Rubin, E, Philip, T, Porgador, A, Berindan-Neagoe, I, Schilsky, R L & Kurzrock, R 2022, ' Comorbidity between lung cancer and COVID-19 pneumonia : role of immunoregulatory gene transcripts in high ACE2-expressing normal lung ', Therapeutic Advances in Medical Oncology, vol. 14, pp. 1-15 . https://doi.org/10.1177/17588359221133893
ACE2 expression; COVID-19; Cancer Expresión ACE2; COVID-19; Cáncer Expressió ACE2; COVID-19; Càncer Background: SARS-CoV-2 (COVID-19) elicits a T-cell antigen-mediated immune response of variable efficacy. To understand this variability, we explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5925932de3f74f03629c6fd6145d1f2
https://hdl.handle.net/11351/8932
https://hdl.handle.net/11351/8932
Autor:
Vladimir Lazar, Razelle Kurzrock, Pierre Saintigny, Jordi Rodon, Gerald Batist, Aliza Ackerstein, Apostolia Maria Tsimberidou, Richard L. Schilsky, J. Jack Lee, Eitan Rubin, Aleksandra Kugel, Fanny Wunder, Jacques Raynaud, Raanan Berger, Jean-Francois Martini, Josep Tabernero, Catherine Bresson, John Mendelsohn, Yohann Loriot, Irene Brana, Jean-Charles Soria, Wilson H. Miller, Mohammad Afshar, Amir Onn, Vincent A. Miller
Publikováno v:
Nature Medicine. 25:751-758
Precision medicine focuses on DNA abnormalities, but not all tumors have tractable genomic alterations. The WINTHER trial ( NCT01856296 ) navigated patients to therapy on the basis of fresh biopsy-derived DNA sequencing (arm A; 236 gene panel) or RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6e337f5a40d49b16bda0db0cc663be
https://doi.org/10.1038/s41591-019-0424-4
https://doi.org/10.1038/s41591-019-0424-4
Autor:
Giorgio Massimini, Angel Porgador, Irene Braña, Alexia Savignoni, Gerald Batist, Eitan Rubin, Ioana Berindan-Neagoe, Jean-Francois Martini, Enriqueta Felip, Catherine Bresson, Fanny Wunder, Marina Sekacheva, Raanan Berger, Nicolas Girard, Jacques Raynaud, Razelle Kurzrock, Benjamin Solomon, Vladimir Lazar, Shai Magidi, Richard L. Schilsky, Josep Tabernero, Amir Onn, Apostolia Maria Tsimberidou, Claudia L. Kleinman, Jean-Charles Soria
Publikováno v:
NPJ Precision Oncology
Scientia
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Scientia
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
The expanding targeted therapy landscape requires combinatorial biomarkers for patient stratification and treatment selection. This requires simultaneous exploration of multiple genes of relevant networks to account for the complexity of mechanisms t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837f2cf4fc270ffe31fed14f74270fb2
https://pubmed.ncbi.nlm.nih.gov/33911192
https://pubmed.ncbi.nlm.nih.gov/33911192
Autor:
Irene Brana, J. Tabernero, Apostolia-Maria Tsimberidou, Wilson H. Miller, Coro Bescos, Richard L. Schilsky, Y. Loriot, Cristina Viaplana, Catherine Bresson, Razelle Kurzrock, Pierre Saintigny, Fanny Wunder, Vladimir Lazar, Raanan Berger, J-C. Soria, Juan Lorente, Eitan Rubin, R. Dienstmann, Paolo Nuciforo, Jordi Rodon
Publikováno v:
Annals of Oncology. 31:S679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5848cf0cf6d87f456ff5d2753afbefd4
https://doi.org/10.1016/j.annonc.2020.08.1076
https://doi.org/10.1016/j.annonc.2020.08.1076
Autor:
Catherine Bresson, Nicolas Girard, Jair Bar, Amir Onn, Eric Raymond, J. Jack Lee, Eitan Rubin, A. Callejo, Benjamin Maurice Solomon, Pierre Saintigny, Razelle Kurzrock, Enriqueta Felip, Brian Leyland-Jones, Vladimir Lazar, Jacques Raynaud, Bruce R. Prouse, Raed Sulaiman, Fanny Wunder, Lyudmila Bazhenova, Guy Berchem
Publikováno v:
Publons
9581 Background: The Worldwide Innovative Network (WIN) Consortium has developed the Simplified Interventional Mapping System (SIMS) algorithm in order to predict treatment response by comparing tumor and normal tissue biopsies on both genomic and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965cbe09b5c22dedf94f921920c80b2b
https://doi.org/10.1200/jco.2020.38.15_suppl.9581
https://doi.org/10.1200/jco.2020.38.15_suppl.9581