Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fanny Vella"'
Autor:
Fanny Vella, Catherine Mallet, Sophie P. Guénin, Nadine Nagel, Francis Cogé, Pascale Chomarat, Jean A. Boutin, François Mailliet, Stephanie Giraudet, Gilles Ferry, Philippe Delagrange, Stéphane Léonce
Publikováno v:
Biochimie. 89:1264-1275
NRH:quinone oxidoreductase 2 (QR2) is a long forgotten oxidoreductive enzyme that metabolizes quinones and binds melatonin. We used the potency of the RNA interference (RNAi)-mediated gene silencing to build a cellular model in which the role of QR2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2497489f21d448c7dab5eba7996938
https://doi.org/10.1016/j.biochi.2007.07.004
https://doi.org/10.1016/j.biochi.2007.07.004
Publikováno v:
Journal of Biological Chemistry. 278:19834-19843
Integrins are cell surface receptors involved in numerous pathological processes such as metastasis invasion and abnormal angiogenesis. To target these receptors, the epidermal growth factor (EGF)-like domain of human complement protease C1r was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ae57f6a844e693db673f447f6b850d
https://doi.org/10.1074/jbc.m301470200
https://doi.org/10.1074/jbc.m301470200
Autor:
Sophie-Pénélope Guenin, Jean A. Boutin, Philippe Delagrange, François Mailliet, Francis Cogé, Marie-Claude Viaud-Massuard, Gilles Ferry, Sylvie Berger, Saïd Yous, Catherine Mallet, Pascale Chomarat, Fanny Vella, Gérald Guillaumet
Publikováno v:
Biochemical pharmacology. 71(1-2)
Melatonin acts through a series of molecular targets: the G-protein coupled receptors, MT1 and MT2, and a third binding site, MT3, recently identified as the enzyme NRH:quinone oxydoreductase 2 (QR2). The relationship between the multiple physiologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a673fbb496c2def5c75b7c6f0531459d
https://pubmed.ncbi.nlm.nih.gov/16293234
https://pubmed.ncbi.nlm.nih.gov/16293234
Publikováno v:
Biochemical pharmacology. 71(1-2)
Quinone reductase 2 has been discovered in 1961 and rediscovered in 1997. Because of its sequence homology with quinone reductase 1, it has been suspected to detoxify quinones. Ten years later, evidences begin to point to a versatile role of this enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b025ec7e3ac13bf7fa7008f95e94e79
https://pubmed.ncbi.nlm.nih.gov/16253210
https://pubmed.ncbi.nlm.nih.gov/16253210
Publikováno v:
Chemico-biological interactions. 151(3)
Quinone reductase 2 is a mammalian cytosolic FAD-dependent enzyme, the activity of which is not supported by conventional nicotinamide nucleotides. An endobiotic substrate has never been reported for this enzyme nor a set of molecular tools, such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61768776b71d26e991ffe9924f929d70
https://pubmed.ncbi.nlm.nih.gov/15733542
https://pubmed.ncbi.nlm.nih.gov/15733542
Autor:
Fanny Vella, Philippe Delagrange, Gilles Ferry, Jean A. Boutin, François Mailliet, Kader Thiam
Publikováno v:
FEBS Letters. (1-2):116-120
Two melatonin receptors (MT1 and MT2) have been cloned. A third melatonin binding site, MT3, is known with remarkable and distinct pharmacological properties. We previously reported the purification of MT3 and identified it as the enzyme dihydronicot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c071aaf92c748267fbc0fdf7b8cffb1c