Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Fanny Aprahamian"'
Autor:
Carolina Alves Costa Silva, Gianmarco Piccinno, Déborah Suissa, Mélanie Bourgin, Gerty Schreibelt, Sylvère Durand, Roxanne Birebent, Marine Fidelle, Cissé Sow, Fanny Aprahamian, Paolo Manghi, Michal Punčochář, Francesco Asnicar, Federica Pinto, Federica Armanini, Safae Terrisse, Bertrand Routy, Damien Drubay, Alexander M. M. Eggermont, Guido Kroemer, Nicola Segata, Laurence Zitvogel, Lisa Derosa, Kalijn F. Bol, I. Jolanda M. de Vries
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Tumor immunosurveillance plays a major role in melanoma, prompting the development of immunotherapy strategies. The gut microbiota composition, influencing peripheral and tumoral immune tonus, earned its credentials among predictors of survi
Externí odkaz:
https://doaj.org/article/93008ed84ad54d8ba4a63ee21aaebb08
Autor:
Giulia Cerrato, Carlota Alvarez-Lucena, Allan Sauvat, Yanhua Hu, Sabrina Forveille, Guo Chen, Sylvère Durand, Fanny Aprahamian, Marion Leduc, Omar Motiño, Lisardo Boscá, Qingbo Xu, Oliver Kepp, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-10 (2023)
Abstract Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing compounds that act on atherosclerosis-relevant cells might have a protective role i
Externí odkaz:
https://doaj.org/article/8050014a17f34ad7a86df5bb6a8fb9fb
Autor:
Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, Vincent Carbonnier, Hui Chen, Valentina Sica, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romain Donne, Chantal Desdouets, Marcelo Simon Sola, Konstantina Kotta, Léa Montégut, Flavia Lambertucci, Didier Surdez, Grossetête Sandrine, Olivier Delattre, Maria Chiara Maiuri, José Manuel Bravo-SanPedro, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-15 (2022)
Abstract Acyl-coenzyme-A-binding protein (ACBP), also known as a diazepam-binding inhibitor (DBI), is a potent stimulator of appetite and lipogenesis. Bioinformatic analyses combined with systematic screens revealed that peroxisome proliferator-activ
Externí odkaz:
https://doaj.org/article/9d621ffca98c4f8181d6d34f52f24bcd
Autor:
Adrien Joseph, Guido Kroemer, Antoine Lafarge, Oliver Kepp, Jonathan Pol, Sylvere Durand, Marion Leduc, Pan Juncheng, Florine Obrist, Judith Michels, Maria Castedo, Allan Sauvat, Giulia Cerrato, Isabelle Martins, Ester Saavedra, Sijing Li, Sarah Lévesque, Fanny Aprahamian, Nitharsshini Nirmalathansan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/7714514c693442aeb5c3fe39dd25252e
Autor:
Layale Youssef, Mélanie Bourgin, Sylvère Durand, Fanny Aprahamian, Deborah Lefevre, Maria Chiara Maiuri, Vincent Marcangeli, Maude Dulac, Guy Hajj-Boutros, Fanny Buckinx, Eva Peyrusqué, Pierrette Gaudreau, José A. Morais, Gilles Gouspillou, Guido Kroemer, Mylène Aubertin-Leheudre, Philippe Noirez
Publikováno v:
Metabolites, Vol 13, Iss 2, p 198 (2023)
Physical activity can be effective in preventing some of the adverse effects of aging on health. High-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) are beneficial interventions for the quality of life of obese o
Externí odkaz:
https://doaj.org/article/fede5081acb74a39b7314b0623845152
Autor:
Norbert J. Tripolt, Sebastian J. Hofer, Peter N. Pferschy, Faisal Aziz, Sylvère Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Mara Waltenstorfer, Tobias Eisenberg, Anna M. A. Obermayer, Regina Riedl, Harald Kojzar, Othmar Moser, Caren Sourij, Heiko Bugger, Abderrahim Oulhaj, Thomas R. Pieber, Matthias Zanker, Guido Kroemer, Frank Madeo, Harald Sourij
Publikováno v:
Nutrients, Vol 15, Iss 3, p 511 (2023)
Metabolic regulation of glucose can be altered by fasting periods. We examined glucose metabolism and metabolomics profiles after 12 h and 36 h fasting in non-obese and obese participants and people with type 2 diabetes using oral glucose tolerance (
Externí odkaz:
https://doaj.org/article/0dabed7feb744df1822e2dc32a15003e
Autor:
Francesca Castoldi, Juliette Humeau, Isabelle Martins, Sylvie Lachkar, Damarys Loew, Florent Dingli, Sylvère Durand, David Enot, Noëlie Bossut, Alexis Chery, Fanny Aprahamian, Yohann Demont, Paule Opolon, Nicolas Signolle, Allan Sauvat, Michaela Semeraro, Lucillia Bezu, Elisa Elena Baracco, Erika Vacchelli, Jonathan G. Pol, Sarah Lévesque, Norma Bloy, Valentina Sica, Maria Chiara Maiuri, Guido Kroemer, Federico Pietrocola
Publikováno v:
Cell Death Discovery, Vol 6, Iss 1, Pp 1-17 (2020)
Abstract Salicylate, the active derivative of aspirin (acetylsalicylate), recapitulates the mode of action of caloric restriction inasmuch as it stimulates autophagy through the inhibition of the acetyltransferase activity of EP300. Here, we directly
Externí odkaz:
https://doaj.org/article/87cf4e0d739f46b498bf36f527c63889
Autor:
Peng Liu, Liwei Zhao, Jonathan Pol, Sarah Levesque, Adriana Petrazzuolo, Christina Pfirschke, Camilla Engblom, Steffen Rickelt, Takahiro Yamazaki, Kristina Iribarren, Laura Senovilla, Lucillia Bezu, Erika Vacchelli, Valentina Sica, Andréa Melis, Tiffany Martin, Lin Xia, Heng Yang, Qingqing Li, Jinfeng Chen, Sylvère Durand, Fanny Aprahamian, Deborah Lefevre, Sophie Broutin, Angelo Paci, Amaury Bongers, Veronique Minard-Colin, Eric Tartour, Laurence Zitvogel, Lionel Apetoh, Yuting Ma, Mikael J. Pittet, Oliver Kepp, Guido Kroemer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Certain chemotherapeutic agents can exert their anticancer effect through indirect immune-dependent mechanism. Here, the authors screen a library of tyrosine kinase inhibitors and show that crizotinib is an effective stimulator of immunogenic cell de
Externí odkaz:
https://doaj.org/article/228ee56caf814e7fbcca341ed093aaed
Autor:
Didac Carmona-Gutierrez, Andreas Zimmermann, Katharina Kainz, Federico Pietrocola, Guo Chen, Silvia Maglioni, Alfonso Schiavi, Jihoon Nah, Sara Mertel, Christine B. Beuschel, Francesca Castoldi, Valentina Sica, Gert Trausinger, Reingard Raml, Cornelia Sommer, Sabrina Schroeder, Sebastian J. Hofer, Maria A. Bauer, Tobias Pendl, Jelena Tadic, Christopher Dammbrueck, Zehan Hu, Christoph Ruckenstuhl, Tobias Eisenberg, Sylvere Durand, Noélie Bossut, Fanny Aprahamian, Mahmoud Abdellatif, Simon Sedej, David P. Enot, Heimo Wolinski, Jörn Dengjel, Oliver Kepp, Christoph Magnes, Frank Sinner, Thomas R. Pieber, Junichi Sadoshima, Natascia Ventura, Stephan J. Sigrist, Guido Kroemer, Frank Madeo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Although ageing is the most important risk factor for chronic ailments, effective interventions remain rare. Here, the authors identify the flavonoid 4,4’-dimethoxychalcone and demonstrate that it extends lifespan and promotes health in multiple or
Externí odkaz:
https://doaj.org/article/5a077fc79ab04bd9a229474d374a66e5
Autor:
Gerasimos Anagnostopoulos, Omar Motiño, Sijing Li, Vincent Carbonnier, Hui Chen, Valentina Sica, Sylvère Durand, Mélanie Bourgin, Fanny Aprahamian, Nitharsshini Nirmalathasan, Romain Donne, Chantal Desdouets, Marcelo Simon Sola, Konstantina Kotta, Léa Montégut, Flavia Lambertucci, Didier Surdez, Grossetête Sandrine, Olivier Delattre, Maria Chiara Maiuri, José Manuel Bravo-San Pedro, Isabelle Martins, Guido Kroemer
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/079b77792a314dfb93dbcdc0d5aaa91b