Výsledky vyhledávání - "Fanny, Szafer"

Fn14·TRAIL fusion protein is oligomerized by TWEAK into a superefficient TRAIL analog

Autor: Efi Makdasi, Michal Dranitzki Elhalel, Kobi Tzdaka, Fanny Szafer, Alexandra Aronin, Noam Shani, Tatyana B. Prigozhina, Shira Amsili

Publikováno v: Cancer letters. 400

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) demonstrates specific anti-cancer activity, but insufficient efficacy in patients. A fusion protein Fn14·TRAIL, that combines soluble TRAIL molecule with a specific TWEAK receptor Fn14,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b2d5ebbe15c1f259c7c4e5fbd0aea0
https://pubmed.ncbi.nlm.nih.gov/28455246

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Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL

Autor: Shira Amsili, Per Edebrink, Tatyana B. Prigozhina, Leonid Grinmann, Michal Dranitzki Elhalel, Mari-Anne Rauvola, Roy Shen, Alexandra Aronin, Noam Shani, Fanny Szafer, Kobi Tzdaka

Publikováno v: Journal of Hematology & Oncology

Non-Hodgkin lymphomas (NHLs) account for 4% of all malignancies. 5-year survival rate increased to 50% with new treatment modalities, however there is need for new effective treatment for the more aggressive, relapsing forms. Recently, CTLA4-FasL, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1c406d19696fbcac4080a607994613
https://doi.org/10.1186/s13045-014-0064-6

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Treatment with a laminin-derived peptide suppresses lupus nephritis

Autor: Rina Ulmansky, Fanny Szafer, Laurence Morel, Dan Eilat, Michal Heilweil, Galina Pizov, Gustavo Mostoslavsky, Mary H. Foster, Ruth Bar-Tana, Yaakov Naparstek, Howard Amital

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 175(8)

The role of DNA as the target for pathogenic lupus autoantibodies in systemic lupus erythematosus is equivocal and renal damage may be due to cross-reactivity of lupus Abs with glomerular components. We have previously shown that lupus autoantibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b3dfc582163b4516048a9f958f54fc
https://pubmed.ncbi.nlm.nih.gov/16210660

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Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis

Autor: Karen, Meir, Daniel, Kitsberg, Irit, Alkalay, Fanny, Szafer, Haim, Rosen, Shoshanna, Shpitzen, Liat Ben, Avi, Bart, Staels, Catherine, Fievet, Vardiella, Meiner, Ingemar, Björkhem, Eran, Leitersdorf

Publikováno v: The Journal of biological chemistry. 277(37)

CYP27-overexpressed transgenic mice were generated with the use of a human full-length CYP27 coding region cloned into a ubiquitous expression vector. Positive transgenic mice were identified by tail DNA genotyping and high fecal 27-hydroxycholestero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::caa5578c75818ce9ba0a7bf73c52d991
https://pubmed.ncbi.nlm.nih.gov/12119285

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Resistance to adjuvant arthritis is due to protective antibodies against heat shock protein surface epitopes and the induction of IL-10 secretion

Autor: Eli Moallem, Yechezkel Kashi, Yaakov Naparstek, Fanny Szafer, Rina Ulmansky, Cyril J. Cohen, Zvi G. Fridlender

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 168(12)

Adjuvant arthritis (AA) is an experimental model of autoimmune arthritis that can be induced in susceptible strains of rats such as inbred Lewis upon immunization with CFA. AA cannot be induced in resistant strains like Brown-Norway or in Lewis rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefa2156e88edbcdb90f1558cf30cac2
https://pubmed.ncbi.nlm.nih.gov/12055266

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