Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Fanny, Lafouresse"'
1
Akademický článek
Evolutionary design of explainable algorithms for biomedical image segmentation
Autor: Kévin Cortacero, Brienne McKenzie, Sabina Müller, Roxana Khazen, Fanny Lafouresse, Gaëlle Corsaut, Nathalie Van Acker, François-Xavier Frenois, Laurence Lamant, Nicolas Meyer, Béatrice Vergier, Dennis G. Wilson, Hervé Luga, Oskar Staufer, Michael L. Dustin, Salvatore Valitutti, Sylvain Cussat-Blanc
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract An unresolved issue in contemporary biomedicine is the overwhelming number and diversity of complex images that require annotation, analysis and interpretation. Recent advances in Deep Learning have revolutionized the field of computer visio
Externí odkaz: https://doaj.org/article/755405e7d248417ea16e00b6baf15051
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2
Akademický článek
Flow cytometry analysis of endothelial cells and subsets of exhausted CD8+ T cells in murine tumor models
Autor: Lucas Blanchard, Estefania Vina, Assia Asrir, Claire Tardiveau, Juliette Coudert, Robin Laffont, Dorian Tarroux, Sarah Bettini, Krystle Veerman, Fanny Lafouresse, Mélanie Pichery, Emilie Mirey, Elisabeth Bellard, Nathalie Ortega, Jean-Philippe Girard
Publikováno v: STAR Protocols, Vol 3, Iss 2, Pp 101444- (2022)
Summary: Here, we present a protocol for flow cytometry analysis of endothelial cells (ECs) and CD8+ T cells in murine tumor models, at baseline and after cancer immunotherapy with anti-PD-1/anti-CTLA-4 antibodies. We provide gating strategies for id
Externí odkaz: https://doaj.org/article/57a2fe6779094c428b30fb54b468b855
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3
Akademický článek
Stochastic asymmetric repartition of lytic machinery in dividing CD8+ T cells generates heterogeneous killing behavior
Autor: Fanny Lafouresse, Romain Jugele, Sabina Müller, Marine Doineau, Valérie Duplan-Eche, Eric Espinosa, Marie-Pierre Puisségur, Sébastien Gadat, Salvatore Valitutti
Publikováno v: eLife, Vol 10 (2021)
Cytotoxic immune cells are endowed with a high degree of heterogeneity in their lytic function, but how this heterogeneity is generated is still an open question. We therefore investigated if human CD8+ T cells could segregate their lytic components
Externí odkaz: https://doaj.org/article/67270014a69b4a8dbeff92ec2f7c3fbe
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4
Akademický článek
Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection
Autor: Amania A. Sheikh, Lucy Cooper, Meiqi Feng, Fernando Souza-Fonseca-Guimaraes, Fanny Lafouresse, Brigette C. Duckworth, Nicholas D. Huntington, James J. Moon, Marc Pellegrini, Stephen L. Nutt, Gabrielle T. Belz, Kim L. Good-Jacobson, Joanna R. Groom
Publikováno v: Cell Reports, Vol 28, Iss 7, Pp 1758-1772.e4 (2019)
Summary: Following infection, inflammatory cues upregulate core transcriptional programs to establish pathogen-specific protection. In viral infections, T follicular helper (TFH) cells express the prototypical T helper 1 transcription factor T-bet. S
Externí odkaz: https://doaj.org/article/cd5c2f99504b4133b0cdd744e3118bd0
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