Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Fanny, Franchini"'
Autor:
Grace Chazan, M.B.B.S., BSc, FRACP, Fanny Franchini, BSc, MSc, DPhil, Roma Shah, MPH, Marliese Alexander, BPharm (Hons), MPH, PhD, Ani John, PhD, Maarten IJzerman, BSc, MSc, PhD, Benjamin Solomon, M.B.B.S., PhD, FRACP
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 8, Pp 100662- (2024)
Introduction: ALK–rearranged advanced NSCLC (aNSCLC) represents 4% of all NSCLCs, and multiple ALK-targeted therapies (ALK-inhibitors) are now available for use. Little is known about changes in treatment patterns, or how prognostic factors and seq
Externí odkaz:
https://doaj.org/article/3eb06d5d1ed3454a8a2475f9e0119edb
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Although several strategies for modelling competing events in discrete event simulation (DES) exist, a methodological gap for the event-specific probabilities and distributions (ESPD) approach when dealing with censored data remains. This
Externí odkaz:
https://doaj.org/article/d06ebcc13dd747928671ed73ef70276d
Autor:
Sophie O’Haire, Fanny Franchini, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Jayesh Desai, Stephen Fox, Maarten IJzerman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract NTRK gene fusions are rare somatic mutations found across cancer types with promising targeted therapies emerging. Healthcare systems face significant challenges in integrating these treatments, with uncertainty in prevalence and optimal tes
Externí odkaz:
https://doaj.org/article/b35f94e22ce342f6b4dba59d58182fb6
Autor:
Yoon-Jung Kang, Sophie O’Haire, Fanny Franchini, Maarten IJzerman, John Zalcberg, Finlay Macrae, Karen Canfell, Julia Steinberg
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Immune checkpoint inhibitors have been approved in the USA for tumours exhibiting mismatch repair deficiency (dMMR), microsatellite instability (MSI), or high tumour mutational burden (TMB), with regulatory and reimbursement applications in
Externí odkaz:
https://doaj.org/article/391e9fff76394c5e90154c7317cef0d7
Autor:
Jae Hong Im, Jon N. Buzzelli, Keaton Jones, Fanny Franchini, Alex Gordon-Weeks, Bostjan Markelc, Jianzhou Chen, Jin Kim, Yunhong Cao, Ruth J. Muschel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Macrophages contribute to tumour progression and response to therapy. Here, the authors show that absence of FGF2 in the tumour microenvironment reduces tumour growth and enhances the anti-tumour immune response by altering macrophage polarization. A
Externí odkaz:
https://doaj.org/article/aac2c94a42384be185bf6c4fce5f6dff
Autor:
Linda Mileshkin, Florian Lordick, Solange Peters, Nick Pavlakis, Deme Karikios, Grace Chazan, Fanny Franchini, Marliese Alexander, Prunella Blinman, Rob Zielinski, David Ball, Gavin Wright, Maarten IJzerman, Benjamin Solomon
Publikováno v:
ESMO Open, Vol 5, Iss 6 (2020)
Objectives To report clinician-perceived changes to cancer service delivery in response to COVID-19.Design Multidisciplinary Australasian cancer clinician survey in collaboration with the European Society of Medical Oncology.Setting Between May and J
Externí odkaz:
https://doaj.org/article/17639bf9b2704e69899687c8dd749713
Autor:
Grigory Ryzhakov, Nathaniel R. West, Fanny Franchini, Simon Clare, Nicholas E. Ilott, Stephen N. Sansom, Samuel J. Bullers, Claire Pearson, Alice Costain, Alun Vaughan-Jackson, Jeremy A. Goettel, Joerg Ermann, Bruce H. Horwitz, Ludovico Buti, Xin Lu, Subhankar Mukhopadhyay, Scott B. Snapper, Fiona Powrie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The Hiccs locus has been associated with susceptibility to colitis in mice. Here the authors identify a Hiccs locus gene encoding Alpha kinase 1 as a potent regulator of intestinal inflammation via modulation of the IL-12/Th1 axis.
Externí odkaz:
https://doaj.org/article/cd1515a1c0414a6e99b0e45f27672c4a
Autor:
Sophie O’Haire, Koen Degeling, Fanny Franchini, Ben Tran, Stephen J Luen, Clara Gaff, Kortnye Smith, Stephen Fox, Jayesh Desai, Maarten IJzerman
Publikováno v:
Targeted oncology. 17(5)
Complex genomic profiling (CGP) has transformed cancer treatment decision making, yet there is a lack of robust and quantifiable evidence for how utilisation of CGP improves patient outcomes.This study evaluated cohort level clinical effectiveness of
Autor:
Jianrong Zhang, Maarten J. IJzerman, Jasmeen Oberoi, Napin Karnchanachari, Rebecca J. Bergin, Fanny Franchini, Paige Druce, Xiaofei Wang, Jon D. Emery
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 166
Over half of patients with lung cancer are diagnosed at a stage when curative treatment is not possible, suggesting an earlier diagnosis could improve outcomes. This comprehensive overview summarises the evidence on 1) times to diagnosis and treatmen
Autor:
Robert Zielinski, Florian Lordick, Benjamin Solomon, Solange Peters, Fanny Franchini, Susana Banerjee, David Ball, Grace Chazan, Deme Karikios, Marliese Alexander, Nick Pavlakis, Linda Mileshkin, Gavin M. Wright, Prunella Blinman, Maarten Joost IJzerman
Publikováno v:
ESMO open, vol. 6, no. 5, pp. 100224
ESMO Open
ESMO Open, 6(5):100224. BMJ
ESMO Open, 6(5):100224. BMJ Publishing Group
ESMO Open
ESMO Open, 6(5):100224. BMJ
ESMO Open, 6(5):100224. BMJ Publishing Group
Background The COVID-19 pandemic has had a vast impact on cancer service delivery around the world. Previously reported results from our international survey of oncology clinicians, conducted through March-April 2020, found that clinicians reported a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f2d2dad76235d3d8c3aa12da395794
https://serval.unil.ch/resource/serval:BIB_C2A577E9F0A6.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_C2A577E9F0A6.P001/REF.pdf