Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fanni Ratzon"'
Publikováno v:
Journal of the American Society of Cytopathology. 12:206-215
Autor:
Sahar Gelfman, Quanli Wang, K. Melodi McSweeney, Zhong Ren, Francesca La Carpia, Matt Halvorsen, Kelly Schoch, Fanni Ratzon, Erin L. Heinzen, Michael J. Boland, Slavé Petrovski, David B. Goldstein
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
While non-coding synonymous and intronic variants are often not under strong selective constraint, they can be pathogenic through affecting splicing or transcription. Here, the authors develop a score that uses sequence context alterations to predict
Externí odkaz:
https://doaj.org/article/416a7ceb757b4b1cb818a138ccea63b5
Autor:
Shanu Modi, Sarat Chandarlapaty, Nancy T. Sklarin, Monica N. Fornier, Neal Rosen, Sujata Patil, Alexia Iasonos, Fanni Ratzon, Fresia Pareja, Rui Wang, Payal Deepak Shah, Joshua Z. Drago, Komal Jhaveri
Purpose:Activating mutations in PIK3CA promote resistance to HER2-targeted therapy in breast cancer; however, inhibition of PI3K alone leads to escape via feedback upregulation of HER3. Combined inhibition of HER2, HER3, and PI3K overcomes this mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ae01f97661fac0629fd8d398512a0d
https://doi.org/10.1158/1078-0432.c.6530615
https://doi.org/10.1158/1078-0432.c.6530615
Autor:
Rui Wang, Alexia Iasonos, Joshua Z. Drago, Komal Jhaveri, Sujata Patil, Sarat Chandarlapaty, Fanni Ratzon, Neal Rosen, Payal D. Shah, Monica Fornier, Shanu Modi, Fresia Pareja, Nancy Sklarin
Publikováno v:
Clinical Cancer Research. 27:3867-3875
Purpose: Activating mutations in PIK3CA promote resistance to HER2-targeted therapy in breast cancer; however, inhibition of PI3K alone leads to escape via feedback upregulation of HER3. Combined inhibition of HER2, HER3, and PI3K overcomes this mech
Publikováno v:
AJSP: Reviews and Reports. 26:188-193
Autor:
David J. Langer, Randy S. D'Amico, Lukas Faltings, John A. Boockvar, Tamika Wong, Madeline Abrams, Deepak Khatri, Mona Li, Christopher G. Filippi, Noah Reichman, Todd Anderson, Nitesh V Patel, Fanni Ratzon, Sherese Fralin
Publikováno v:
World Neurosurgery. 143:38-45
Background The major difficulty in treating glioblastoma stems from the intrinsic privileged nature of the brain. This complicates therapy, as many traditionally potent chemotherapeutics cannot access their target sites in the brain. Several techniqu
Autor:
Komal, Jhaveri, Joshua Z, Drago, Payal Deepak, Shah, Rui, Wang, Fresia, Pareja, Fanni, Ratzon, Alexia, Iasonos, Sujata, Patil, Neal, Rosen, Monica N, Fornier, Nancy T, Sklarin, Sarat, Chandarlapaty, Shanu, Modi
Publikováno v:
Clin Cancer Res
BACKGROUND: Activating mutations in PIK3CA promote resistance to HER2-targeted therapy in breast cancer, however inhibition of PI3K alone leads to escape via feedback upregulation of HER3. Combined inhibition of HER2, HER3 and PI3K overcomes this mec
Publikováno v:
Journal of the American Podiatric Medical Association. 108:430-433
We report on the unusual presentation of a schwannoma. Aside from the aberrant dorsolateral anatomical presentation, ultrasonography revealed not only peripheral vascularity but also internal vascularity. Internal vascularity often suggests a maligna
Publikováno v:
International journal of surgical pathology. 27(5)
Germ cell neoplasia in situ is the initial manifestation for invasive germ cell tumor. Further progression will result in intratubular germ cell tumor with the majority being intratubular seminoma or intratubular embryonal carcinoma. Intratubular ter
Autor:
Quanli Wang, Zhong Ren, Erin L. Heinzen, Kelly Schoch, K. Melodi McSweeney, Sahar Gelfman, David Goldstein, Michael J. Boland, Slavé Petrovski, Francesca La Carpia, Fanni Ratzon, Matt Halvorsen
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Identifying the underlying causes of disease requires accurate interpretation of genetic variants. Current methods ineffectively capture pathogenic non-coding variants in genic regions, resulting in overlooking synonymous and intronic variants when s