Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fanju W Meng"'
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008553 (2019)
Many tissues rely on resident stem cell population to maintain homeostasis. The balance between cell proliferation and differentiation is critical to permit tissue regeneration and prevent dysplasia, particularly following tissue damage. Thus, unders
Externí odkaz:
https://doaj.org/article/4781e34681e848e283b1f4832b964034
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: Physiological and pathological stimuli result in distinct forms of cardiac hypertrophy, but the molecular regulation comparing the two, especially at the DNA methylation level, is not well understood.Methods: We conducted an in vitro stud
Externí odkaz:
https://doaj.org/article/047737bcdbf14ab99622a302b3ec8423
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 226-240 (2020)
Summary: Robust production of terminally differentiated cells from self-renewing resident stem cells is essential to maintain proper tissue architecture and physiological functions, especially in high-turnover tissues. However, the transcriptional ne
Externí odkaz:
https://doaj.org/article/ca0d50be66804f898d97d476b50e326b
Autor:
Fanju W. Meng, Benoît Biteau
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 906-914 (2015)
Adult organs and their resident stem cells are constantly facing the challenge of adapting cell proliferation to tissue demand, particularly in response to environmental stresses. Whereas most stress-signaling pathways are conserved between progenito
Externí odkaz:
https://doaj.org/article/78858223473c45e19e538d639167f36f
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Genome-wide chromatin state underlies gene expression potential and cellular function. Epigenetic features and nucleosome positioning contribute to the accessibility of DNA, but widespread regulators of chromatin state are largely unknown. Our study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d73d9d6001814956b71874ad709e196
http://link.springer.com/article/10.1038/s41467-020-18821-x
http://link.springer.com/article/10.1038/s41467-020-18821-x
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 226-240 (2020)
Stem Cell Reports
Stem Cell Reports
Summary Robust production of terminally differentiated cells from self-renewing resident stem cells is essential to maintain proper tissue architecture and physiological functions, especially in high-turnover tissues. However, the transcriptional net
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ae008ff04a486d20649da8165bbb93
https://doi.org/10.1016/j.stemcr.2020.01.003
https://doi.org/10.1016/j.stemcr.2020.01.003
Activation of endogenous retroviruses leads to widespread transcriptional reprograming, affecting innate immune activation, metabolic control, and development. We find that the histone variant H2A.Z plays a central role in orchestrating these respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::923064133aa3ac8a1862f9d5717bccc7
https://doi.org/10.1101/2022.03.31.486614
https://doi.org/10.1101/2022.03.31.486614
Publikováno v:
Dev Dyn
Background Cell fate decisions are governed by interactions between sequence-specific transcription factors and a dynamic chromatin landscape. Zebrafish offer a powerful system for probing the mechanisms that drive these cell fate choices, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b7c90b8d0b526699632025248842ae
https://europepmc.org/articles/PMC8976701/
https://europepmc.org/articles/PMC8976701/
BackgroundCell fate decisions are governed by interactions between sequence-specific transcription factors and a dynamic chromatin landscape. Zebrafish offer a powerful system for probing the mechanisms that drive these cell fate choices, especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10051c56a480a69dd340b3f5ad217902
https://doi.org/10.1101/2021.06.22.447589
https://doi.org/10.1101/2021.06.22.447589
Autor:
Fanju W. Meng, Patrick J. Murphy
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-2 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-2 (2021)
Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward tow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f9d36585a88b91463a1cc3f7c04704
https://pubmed.ncbi.nlm.nih.gov/34017055
https://pubmed.ncbi.nlm.nih.gov/34017055