Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Fani Zervou"'
Autor:
Achilles Anagnostopoulos, Penelope-Georgia Papayanni, Asimina Bouinta, Fani Zervou, Evangelia Yannaki, Garyfalia Karponi
Publikováno v:
Human Gene Therapy Methods. 29:220-227
Stable gene marking and effective engraftment of gene-modified CD34+ hematopoietic stem cells is a prerequisite for gene therapy success but may be challenged by the inevitable cryopreservation of the final product prior to extensive quality assuranc
Autor:
George Stamatoyannopoulos, Varnavas Constantinou, Garyfalia Karponi, Achilles Anagnostopoulos, Fani Zervou, Evangelia Yannaki, Penelope-Georgia Papayanni, Asimina Bouinta
Publikováno v:
Transfusion. 57:1031-1039
Background Hematopoietic stem cell mobilization and leukapheresis in adult patients with β-thalassemia have recently been optimized in the context of clinical trials for obtaining hematopoietic stem cells for thalassemia gene therapy. In some patien
Autor:
Garyfalia, Karponi, Penelope-Georgia, Papayanni, Fani, Zervou, Asimina, Bouinta, Achilles, Anagnostopoulos, Evangelia, Yannaki
Publikováno v:
Human gene therapy methods. 29(5)
Stable gene marking and effective engraftment of gene-modified CD34(+) hematopoietic stem cells is a prerequisite for gene therapy success but may be challenged by the inevitable cryopreservation of the final product prior to extensive quality assura
Autor:
Varnavas C, Constantinou, Asimina, Bouinta, Garyfalia, Karponi, Fani, Zervou, Penelope-Georgia, Papayanni, George, Stamatoyannopoulos, Achilles, Anagnostopoulos, Evangelia, Yannaki
Publikováno v:
Transfusion. 57(4)
Hematopoietic stem cell mobilization and leukapheresis in adult patients with β-thalassemia have recently been optimized in the context of clinical trials for obtaining hematopoietic stem cells for thalassemia gene therapy. In some patients, however
Autor:
Carsten W. Lederer, Nikolaos Zogas, Michel Sadelain, Marina Kleanthous, Nikoletta Psatha, Garyfalia Karponi, Constantinos Tsatalas, George Stamatoyannopoulos, Jennifer E. Adair, Evangelia Yannaki, Achilles Anagnostopoulos, Isabelle Riviere, Fani Zervou
Publikováno v:
Blood
Globin gene therapy requires abundant numbers of highly engraftable, autologous hematopoietic stem cells expressing curative levels of β-globin on differentiation. In this study, CD34+ cells from 31 thalassemic patients mobilized with hydroxyurea+gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172387ad7bd5feace619fcaf3960fd42
https://europepmc.org/articles/PMC4520876/
https://europepmc.org/articles/PMC4520876/
Autor:
Asimina Bouinta, Evangelia Yannaki, Erica C. Jonlin, Garyfalia Karponi, Varnavas Constantinou, Achilles Anagnostopoulos, Varvara Tachynopoulou, Fani Zervou, George Stamatoyannopoulos, Konstantina Kotta, Thalia Papayannopoulou
Publikováno v:
Human gene therapy. 24(10)
Successful stem cell gene therapy requires high numbers of genetically engineered hematopoietic stem cells collected using optimal mobilization strategies. Here we focus on stem cell mobilization strategies for thalassemia and present the results of
Autor:
Thalia Papayannopoulou, George Stamatoyannopoulos, Varnavas Constantinou, Evangelia Yannaki, Athanasios Fassas, Achilles Anagnostopoulos, Garyfalia Karponi, Erica C. Jonlin, Ioannis Batsis, Panayotis Kaloyannidis, Angeliki Xagorari, Konstantia Kotta, Asimina Bouinta, Fani Zervou, Pamela S. Becker, Varvara Tahynopoulou, Nikoleta Psatha, Aglaia Athanassiadou
The safety and efficacy of hematopoietic stem cell (HSC) mobilization was investigated in adult splenectomized (SPL) and non-SPL patients with thalassemia major, in two clinical trials, using different mobilization modes: granulocyte-colony-stimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336a95e4fde6003f13e791b86e48de8c
https://europepmc.org/articles/PMC3255592/
https://europepmc.org/articles/PMC3255592/
Autor:
Asimenia Bouinta, Varvara Tahynopoulou, Nikoleta Psatha, Varnavas Constantinou, Panayotis Kaloyannidis, Erica C. Jonlin, Ioannis Batsis, Pamela S. Becker, Aglaia Athanassiadou, Garyfalia Karponi, Achilles Anagnostopoulos, George Stamatoyannopoulos, Konstantia Kotta, Thalia Papayannopoulou, Angeliki Xagorari, Evangelia Yannaki, Athanasios Fassas, Fani Zervou
Publikováno v:
Blood. 118:166-166
166[][1] In preparation for a trial for gene therapy of thalassemia, we investigated the safety and efficacy of stem cell mobilization in adult patients with severe thalassemia using either GCSF or Plerixafor. We first assessed mobilization with G-CS
Autor:
Elisavet Georgiadou, George Kiriazis, Maria Papathanasiou, Achilles Anagnostopoulos, Ioannis Batsis, Evangelia Yannaki, Varnavas Konstantinou, Ioanna Sakellari, Despina Mallouri, Panayotis Kaloyannidis, Aliki Xoheli, Fani Zervou
Publikováno v:
Blood. 118:1999-1999
Abstract 1999 Infections are major barriers for a favorable outcome following stem cell transplantation (SCT) and their prevention is a significant task in the clinical practice. Vaccinations are well established strategies to reduce the risk of vacc
Autor:
Varvara Tahynopoulou, Panayotis Kaloyannidis, Angeliki Xagorari, Fani Zervou, Evangelia Yannaki, Garyfalia Karponi, Athanasios Fassas, Thalia Papayannopoulou, George Stamatoyannopoulos, Pamela S. Becker, Erica C. Jonlin, Ioannis Batsis, Achilles Anagnostopoulos, Varnavas Constantinou
Publikováno v:
Blood. 114:2150-2150
Abstract 2150 Poster Board II-127 For gene therapy (GT) of thalassemia (TH), high numbers of genetically-modified hematopoietic stem cells (HSCs) are required to effectively compete for niche space in the hypercellular thalassemic bone marrow (bm). M