Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fangzhou Xiao"'
Architectural Principles for Characterizing the Performance of Antithetic Integral Feedback Networks
Publikováno v:
iScience, Vol 14, Iss , Pp 277-291 (2019)
Summary: As we begin to design increasingly complex synthetic biomolecular systems, it is essential to develop rational design methodologies that yield predictable circuit performance. Here we apply mathematical tools from the theory of control and d
Externí odkaz:
https://doaj.org/article/f764f0f14a584c268232e98c0ece11fc
Publikováno v:
eLife, Vol 9 (2020)
Key enzymatic processes use the nonequilibrium error correction mechanism called kinetic proofreading to enhance their specificity. The applicability of traditional proofreading schemes, however, is limited because they typically require dedicated st
Externí odkaz:
https://doaj.org/article/26083f21a6e147338ee57f20c2c362e6
Publikováno v:
bioRxiv
Balanced biosynthesis is the hallmark of bacterial cell physiology, where the concentrations of stable proteins remain steady. However, this poses a conceptual challenge to modeling the cell-cycle and cell-size controls in bacteria, as prevailing con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c74937b9aed2fc1e567caad8cfd0d2c
https://europepmc.org/articles/PMC10246017/
https://europepmc.org/articles/PMC10246017/
Metabolic dynamics such as stability of steady states, oscillations, lags and growth arrests in stress responses are important for microbial communities in human health, ecology, and metabolic engineering. Yet it is hard to model due to sparse data a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6afbbc97723ea0419dd770f98cde9f2
https://doi.org/10.1101/2023.03.23.533708
https://doi.org/10.1101/2023.03.23.533708
Autor:
Fangzhou Xiao, Galstyan, Vahe
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/6/2024, Vol. 121 Issue 32, p1-2, 2p
Publikováno v:
2021 European Control Conference (ECC).
Intercommunication of the microbiome-gut-brain axis occurs through various signaling pathways including the vagus nerve, immune system, endocrine/paracrine, and bacteria-derived metabolites. But how these pathways integrate to influence cognition rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b066b816d0c3b0123bf85edd626073
https://doi.org/10.23919/ecc54610.2021.9655216
https://doi.org/10.23919/ecc54610.2021.9655216
Architectural Principles for Characterizing the Performance of Antithetic Integral Feedback Networks
Publikováno v:
iScience, Vol 14, Iss, Pp 277-291 (2019)
iScience
iScience
Summary As we begin to design increasingly complex synthetic biomolecular systems, it is essential to develop rational design methodologies that yield predictable circuit performance. Here we apply mathematical tools from the theory of control and dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b79f2812ca31f88151dbe685227ae86
http://www.sciencedirect.com/science/article/pii/S2589004219301014
http://www.sciencedirect.com/science/article/pii/S2589004219301014
Publikováno v:
Cell Systems. 7:352-355
Transcription is an episodic process characterized by probabilistic bursts; but how the transcriptional noise from these bursts is modulated by cellular physiology remains unclear. Using simulations and single-molecule RNA counting, we examined how c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ee4905bd0ed2efa39d146df1cd6c03
https://doi.org/10.1016/j.cels.2018.10.003
https://doi.org/10.1016/j.cels.2018.10.003