Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Fangzhi Han"'
Autor:
Weizhi Ge, Xinyi Chen, Fangzhi Han, Zhongquan Liu, Tianpeng Wang, Mengmeng Wang, Yue Chen, Yahui Ding, Quan Zhang
Publikováno v:
Molecules, Vol 23, Iss 12, p 3345 (2018)
Cucurbitacin B shows potent activity against tumor cells, but its high toxicity limits its application in the clinic. A series of cucurbitacin B derivatives was synthesized and evaluated for their anti-hepatocellular carcinoma (HCC) activities agains
Externí odkaz:
https://doaj.org/article/f72f21b2083049b397eb4fe0bb61fe5c
Autor:
Fangzhi Han, Guangju Liu, Xiuhe Zhao, Shunshun Du, Yahui Ding, Quan Zhang, Huiting Deng, Liang Wang, Yue Chen
Publikováno v:
Organicbiomolecular chemistry. 20(20)
Total synthesis of rakicidin F was accomplished in 20 linear steps (0.68% overall yield), which enabled the configural determination of its six stereogenic centers as 2
Publikováno v:
Organic letters. 23(18)
The absolute configuration of rakicidin C was predicted by comparison of optical rotation data and absolute configuration of APD-cyclic depsipeptides and further determined by total synthesis. The absolute configuration of five chiral centers was det
Autor:
Quan Zhang, Liang Wang, Guangju Liu, Yue Chen, Xuhai Zhang, Yahui Ding, Fangzhi Han, Yijing Wu
Publikováno v:
Organic letters. 23(13)
The 15-membered cyclic depsipeptide boholamide A and an epimer were prepared by total synthesis for the first time, thus leading to a revision of C6 stereochemistry in the originally proposed structure of natural boholamide A. This convergent route f
Autor:
Zhongquan Liu, Tianpeng Wang, Yahui Ding, Quan Zhang, Mengmeng Wang, Fangzhi Han, Yue Chen, Xin Hao, Chen Ning, Weizhi Ge
Publikováno v:
European Journal of Medicinal Chemistry. 166:445-469
Triple-negative breast cancer (TNBC) is the most aggressive cancers with a high recurrence rate and rapidly acquired drug resistance among various breast cancer subtypes. There is no specific drug for treatment of TNBC. Discovery of therapeutic agent
Autor:
Zhongquan Liu, Tianpeng Wang, Yue Chen, Quan Zhang, Mengmeng Wang, Weizhi Ge, Xinyi Chen, Yahui Ding, Fangzhi Han
Publikováno v:
Molecules, Vol 23, Iss 12, p 3345 (2018)
Molecules
Volume 23
Issue 12
Molecules
Volume 23
Issue 12
Cucurbitacin B shows potent activity against tumor cells, but its high toxicity limits its application in the clinic. A series of cucurbitacin B derivatives was synthesized and evaluated for their anti-hepatocellular carcinoma (HCC) activities agains