Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Fangxuan Han"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Profound progress has been made in cancer treatment in the past three decades. However, drug resistance remains prevalent and a critical challenge. Drug resistance can be attributed to oncogenes mutations, activated defensive mechanisms, ATP-bind cas
Externí odkaz:
https://doaj.org/article/5dbc2c5ea46e4a549b44fa62cdfad137
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Cancer is the second leading cause of death worldwide. Specially, the high incidence rate and prevalence of drug resistance have rendered prostate cancer (PCa) a great threat to men’s health. Novel modalities with different structures or mechanisms
Externí odkaz:
https://doaj.org/article/bc0d25834ffd4a418085da7de37c6216
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The initial responses to standard chemotherapies among prostate cancer (PCa) patients are usually significant, while most of them will finally develop drug resistance, rendering them with limited therapies. To discover new regimens for the treatment
Externí odkaz:
https://doaj.org/article/877c0ac6218444509e1adc1381d932d6
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236523 (2020)
BackgroundGefitinib is an orally potent and selective ATP-competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase and is commonly used to treat locally advanced or metastatic non-small-cell lung cancer (NSCLC) with sensitive
Externí odkaz:
https://doaj.org/article/d0ba6929004244b996136b77f1ff6de0
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have been developed, but most of them fail in clinical trials due to severe
Externí odkaz:
https://doaj.org/article/d1d9120cdd4546e89f60f84f4c11c05d
Autor:
Qing-Mei Ye, Xiaozhen Ji, Bin Wang, Miao Yu, Jin Cai, Weinv Zeng, Weikang Chen, Fangxuan Han, Guolei Huang, Caijuan Zheng
Publikováno v:
Journal of Oncology.
Efficient screening of anticancer agents is in urgent need to develop new drugs that combat malignant tumors and drug resistance. In this study, a combined strategy composed by solvent partition and HPLC fractionation was developed to generate an her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a8bec6d3b74249bd7474b57ff6ffb4
Autor:
Qing-Mei, Ye, Xiaozhen, Ji, Bin, Wang, Miao, Yu, Jin, Cai, Weinv, Zeng, Weikang, Chen, Fangxuan, Han, Guolei, Huang, Caijuan, Zheng
Publikováno v:
Journal of oncology. 2022
Efficient screening of anticancer agents is in urgent need to develop new drugs that combat malignant tumors and drug resistance. In this study, a combined strategy composed by solvent partition and HPLC fractionation was developed to generate an her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65f5182cc7bf39b441831249d13841a8
https://pubmed.ncbi.nlm.nih.gov/35251179
https://pubmed.ncbi.nlm.nih.gov/35251179
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
Multidrug resistance (MDR) resulting from different defensive mechanisms in cancer is one of the major obstacles of clinical treatment. To circumvent MDR many reversal agents have been developed, but most of them fail in clinical trials due to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2b89e7f64cfd3b94d437dfebe6aae5