Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Fangwen Rao"'
Autor:
Athanasia D. Panopoulos, Matteo D'Antonio, Paola Benaglio, Roy Williams, Sherin I. Hashem, Bernhard M. Schuldt, Christopher DeBoever, Angelo D. Arias, Melvin Garcia, Bradley C. Nelson, Olivier Harismendy, David A. Jakubosky, Margaret K.R. Donovan, William W. Greenwald, KathyJean Farnam, Megan Cook, Victor Borja, Carl A. Miller, Jonathan D. Grinstein, Frauke Drees, Jonathan Okubo, Kenneth E. Diffenderfer, Yuriko Hishida, Veronica Modesto, Carl T. Dargitz, Rachel Feiring, Chang Zhao, Aitor Aguirre, Thomas J. McGarry, Hiroko Matsui, He Li, Joaquin Reyna, Fangwen Rao, Daniel T. O'Connor, Gene W. Yeo, Sylvia M. Evans, Neil C. Chi, Kristen Jepsen, Naoki Nariai, Franz-Josef Müller, Lawrence S.B. Goldstein, Juan Carlos Izpisua Belmonte, Eric Adler, Jeanne F. Loring, W. Travis Berggren, Agnieszka D'Antonio-Chronowska, Erin N. Smith, Kelly A. Frazer
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 1086-1100 (2017)
Summary: Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful model systems for examining how genetic variation affects biology and disease. Here we describe the iPSCORE resource: a collection of systematically de
Externí odkaz:
https://doaj.org/article/c8ae55149e0944118b67d5bad7b79cfa
Autor:
Dalal N Pasha, Jason T Davis, Fangwen Rao, Yuqing Chen, Gen Wen, Maple M Fung, Manjula Mahata, Kuixing Zhang, Danuta Trzebinska, Maja Mustapic, C Makena Hightower, Michael S Lipkowitz, Ming Ji, Michael G Ziegler, Caroline M Nievergelt, Daniel T O'Connor
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82956 (2013)
Elevated sympathetic activity is associated with kidney dysfunction. Here we used twin pairs to probe heritability of GFR and its genetic covariance with other traits.We evaluated renal and adrenergic phenotypes in twins. GFR was estimated by CKD-EPI
Externí odkaz:
https://doaj.org/article/2e704158114f4976a3473b375473c6dc
Autor:
Sylvia M. Evans, Frauke Drees, Naoki Nariai, Lawrence S.B. Goldstein, Chang Zhao, Neil C. Chi, Erin N. Smith, Jonathan D. Grinstein, Olivier Harismendy, Rachel Feiring, Aitor Aguirre, Agnieszka D'Antonio-Chronowska, Eric Adler, Matteo D’Antonio, Kelly A. Frazer, William W. Greenwald, Yuriko Hishida, Fangwen Rao, Juan Carlos Izpisua Belmonte, Hiroko Matsui, Bernhard M. Schuldt, Sherin Hashem, KathyJean Farnam, Victor Borja, Paola Benaglio, Melvin Garcia, Jonathan Okubo, Franz-Josef Müller, Bradley C. Nelson, Veronica Modesto, He Li, Kenneth E. Diffenderfer, Thomas J. McGarry, Roy Williams, Margaret K.R. Donovan, Carl T. Dargitz, Gene W. Yeo, David Jakubosky, Megan Cook, Kristen Jepsen, Daniel T. O'Connor, Carl A. Miller, Christopher DeBoever, Joaquin Reyna, Athanasia D. Panopoulos, Angelo Arias, Jeanne F. Loring, W. Travis Berggren
Publikováno v:
Stem Cell Reports
Stem cell reports, vol 8, iss 4
Stem cell reports
Stem Cell Reports, Vol 8, Iss 4, Pp 1086-1100 (2017)
Stem cell reports, vol 8, iss 4
Stem cell reports
Stem Cell Reports, Vol 8, Iss 4, Pp 1086-1100 (2017)
Summary Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful model systems for examining how genetic variation affects biology and disease. Here we describe the iPSCORE resource: a collection of systematically der
Autor:
Nilima Biswas, Andrew J. Schork, Caroline M. Nievergelt, Kuixing Zhang, Zhiyun Wei, Grant W. Montgomery, Manjula Mahata, Adam X. Maihofer, Nicholas G. Martin, Beben Benyamin, Bruce A. Hamilton, Fangwen Rao, Nicholas J. Schork, Vivian Hook, John Whitfield, Daniel T. O'Connor, Mats Stridsberg, Geert W. Schmid-Schönbein
Publikováno v:
Human molecular genetics, vol 26, iss 1
Chromogranins are pro-hormone secretory proteins released from neuroendocrine cells, with effects on control of blood pressure. We conducted a genome-wide association study for plasma catestatin, the catecholamine release inhibitory peptide derived f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f3a277e813512934eea8ea0bcb6ef0
https://escholarship.org/uc/item/4qq2h46w
https://escholarship.org/uc/item/4qq2h46w
Autor:
Zhiyun Wei, Tomi Pastinen, C. Makena Hightower, Jason J. Corneveaux, Jose Pablo Miramontes-Gonzalez, Caroline M. Nievergelt, Milton H. Saier, Adam X. Maihofer, Matthew J. Huentelman, Kuixing Zhang, Eleazar Eskin, Daniel T. O'Connor, Eric I. Sun, Jill Waalen, Georg Ehret, Manjula Mahata, Fangwen Rao, Andrew J. Schork, Nicholas J. Schork
Publikováno v:
Journal of the American College of Cardiology, Vol. 63, No 15 (2014) pp. 1542-55
Zhang, K; Huentelman, MJ; Rao, F; Sun, EI; Corneveaux, JJ; Schork, AJ; et al.(2014). Genetic implication of a novel thiamine transporter in human hypertension. Journal of the American College of Cardiology, 63(15), 1542-1555. doi: 10.1016/j.jacc.2014.01.007. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8c93v255
Zhang, K; Huentelman, MJ; Rao, F; Sun, EI; Corneveaux, JJ; Schork, AJ; et al.(2014). Genetic implication of a novel thiamine transporter in human hypertension. Journal of the American College of Cardiology, 63(15), 1542-1555. doi: 10.1016/j.jacc.2014.01.007. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8c93v255
Objectives: This study coupled 2 strategies - trait extremes and genome-wide pooling - to discover a novel blood pressure (BP) locus that encodes a previously uncharacterized thiamine transporter. Background: Hypertension is a heritable trait that re
Autor:
Jill Waalen, Daniel T. O'Connor, Caroline M. Nievergelt, Kuixing Zhang, Dekker C. Deacon, Maple M. Fung, Fangwen Rao, Andrew J. Schork, Nicholas J. Schork, Neil C. Chi
Publikováno v:
Journal of the American College of Cardiology. 63:358-368
Objectives The goal of this study was to understand the role of genetic variation in the catecholamine biosynthetic pathway for control of human heart rate (HR). Background Human HR is an integrated cardiovascular trait predictive of morbidity and su
Publikováno v:
Acta obstetricia et gynecologica Scandinavica. 96(6)
Adenomyosis is a disorder of uterus in which endometrial glands and stroma are present within the uterine musculature. The main clinical manifestations are dysmenorrhea and menorrhagia. Adenomyosis has a great impact on both the quality of life and f
Autor:
Laurent Taupenot, Zhiyun Wei, Kuixing Zhang, C. Makena Hightower, Jose Pablo Miramontes-Gonzalez, Caroline M. Nievergelt, Nilima Biswas, Michael G. Ziegler, Nina Elkelis, Andrew J. Schork, Manjula Mahata, Mats Stridsberg, Fangwen Rao, Daniel T. O'Connor
Publikováno v:
Journal of Neurochemistry. 127:750-761
The Syrian Cardiomyopathic Hamster (BIO-14.6/53.58 strains) model of cardiac failure, resulting from naturally occurring deletion at the SGCD (delta-sarcoglycan) locus, displays widespread disturbances in catecholamine metabolism. Rare Mendelian myop
Autor:
Fangwen Rao, Bertrand L. Jaber, Sun Woo Kang, Wenyi Zhang, Paweena Susantitaphong, Daniel T. O'Connor, Mary C. Perianayagam
Publikováno v:
Nephron Clinical Practice. 122:107-113
Background: Kallikrein-1 (KLK1) is a highly conserved serine protease that is expressed in the kidney and involved in blood pressure regulation. The activity of this enzyme is diminished in acute kidney injury (AKI). Methods: We first evaluated the p
Autor:
Caroline M. Nievergelt, Haiyan Wang, Dingfang Bu, Fang Wang, Xingyu Wang, Ying Liu, Daniel T. O'Connor, Yu Liang, Fangwen Rao, Hong Zhang, Luxia Zhang, Lisheng Liu, Jia Han, Yuqing Chen
Publikováno v:
Kidney International. 83:733-740
Uromodulin (UMOD) genetic variants cause familial juvenile hyperuricemic nephropathy, characterized by hyperuricemia, decreased renal excretion of UMOD and uric acid; such findings suggest a role for UMOD in the regulation of plasma uric acid. We scr