Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fangshuo Zheng"'
Autor:
Qin Yang, Zifeng Huang, Yangfu Luo, Fangshuo Zheng, Yida Hu, Hui Liu, Shuzhen Zhu, Miaoqing He, Demei Xu, Yun Li, Min Yang, Yi Yang, Xiaobo Wei, Xiaoya Gao, Wei Wang, Junhong Ma, Yuanlin Ma, Xuefeng Wang, Qing Wang
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 470-483 (2019)
Background: NACHT and WD repeat domain-containing protein 1 (Nwd1) is a member of the innate immune protein subfamily. Nwd1 contributes to the androgen receptor signaling pathway and is involved in axonal growth. However, the mechanisms that underlie
Externí odkaz:
https://doaj.org/article/6da0a74d7fee487a89a78bf7d57cbca6
Autor:
Jinghui Lei, Xiaoyu Jiang, Daoyuan Huang, Ying Jing, Shanshan Yang, Lingling Geng, Yupeng Yan, Fangshuo Zheng, Fang Cheng, Weiqi Zhang, Juan Carlos Izpisua Belmonte, Guang-Hui Liu, Si Wang, Jing Qu
Publikováno v:
Protein & Cell.
Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes in cellular oxygen levels, is closely associated with a wide range of physiological and pathological conditions. However, its differential impacts on vascular cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5fd525c9dbf321643ec494819f0a8d
https://doi.org/10.1093/procel/pwad027
https://doi.org/10.1093/procel/pwad027
Autor:
Shuzhen Zhu, Yida Hu, Qing Wang, Yun Li, Wei Wang, Min Yang, Fangshuo Zheng, Xiaobo Wei, Yuanlin Ma, Demei Xu, Yangfu Luo, Miaoqing He, Yi Yang, Xiaoya Gao, Junhong Ma, Hui Liu, Qin Yang, Xuefeng Wang, Zifeng Huang
Publikováno v:
EBioMedicine
Background NACHT and WD repeat domain-containing protein 1 (Nwd1) is a member of the innate immune protein subfamily. Nwd1 contributes to the androgen receptor signaling pathway and is involved in axonal growth. However, the mechanisms that underlie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a49ac86b31094257f371754aef460ee8
http://europepmc.org/articles/PMC6796588
http://europepmc.org/articles/PMC6796588
Publikováno v:
Biochemical and Biophysical Research Communications. 484:450-455
The AMP-activated protein kinase (AMPK) is a key energy sensor. Its activator metformin could suppress epileptogenesis in the pentylenetetrazol (PTZ) kindling model. However, the effect of metformin on the acute and chronic seizures has not been stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7897bfe892d519334d44c011e10a9e1f
https://doi.org/10.1016/j.bbrc.2017.01.157
https://doi.org/10.1016/j.bbrc.2017.01.157
Autor:
Xin Tian, Xuefeng Wang, Demei Xu, Binglin Zhu, Yanke Zhang, Fangshuo Zheng, Xi Lu, Yuanlin Ma, Yun Li, Xin Xu, Yang Yong
Publikováno v:
Science Advances
GPR40 modulates epileptic seizure and NMDA receptor function through the regulation of NR2A and NR2B surface expression.
Epilepsy is a common neurological disease, and approximately 30% of patients do not respond adequately to antiepileptic drug
Epilepsy is a common neurological disease, and approximately 30% of patients do not respond adequately to antiepileptic drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c373228d4cf88b553a0227ded2afaddc
https://pubmed.ncbi.nlm.nih.gov/30345361
https://pubmed.ncbi.nlm.nih.gov/30345361
Autor:
Yong Yang, Fangshuo Zheng, Qin Yang, Feng Liu, Yun Li, Xin Xu, Yanke Zhang, Xuefeng Wang, Shanshan Lu, Xin Tian
Publikováno v:
Neuroscience. 367
Cluster of differentiation 36 (CD36) belongs to the class B scavenger receptor family. CD36 is a glycoprotein found on the surface of various cell types and has been implicated in the mechanism of numerous central nervous system (CNS) diseases. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d120d4ae74acdce7989d1d694def4eb0
https://pubmed.ncbi.nlm.nih.gov/29111364
https://pubmed.ncbi.nlm.nih.gov/29111364
Publikováno v:
Oncotarget
Epilepsy is the most prevalent chronic neurological disorder, and its pathological mechanism indicates that an imbalance between excitatory and inhibitory neurotransmission leads to neuronal hyperexcitability. Previous studies have suggested that dl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d57c3cabca2a0007654458db3fcd094
https://pubmed.ncbi.nlm.nih.gov/29228686
https://pubmed.ncbi.nlm.nih.gov/29228686
Autor:
Yanke Zhang, Yun Li, Pengfei Fu, Shanshan Lu, Fei Xiao, Yong Yang, Yan Xiong, Qin Yang, Baobing Gao, Fangshuo Zheng, Xuefeng Wang
Publikováno v:
Frontiers in Molecular Neuroscience
Phosphodiesterase regulates the homeostasis of cAMP and cGMP, which increase the strength of excitatory neural circuits and/or decrease inhibitory synaptic plasticity. Abnormally synchronized synaptic transmission in the brain leads to seizures. A ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feabaad46cf15642a08c6035a7aaca1a
https://pubmed.ncbi.nlm.nih.gov/28439226
https://pubmed.ncbi.nlm.nih.gov/28439226
Publikováno v:
CNS drugs. 30(8)
Seizure following traumatic brain injury (TBI) constitutes a common complication that requires effective prevention to improve the outcome of TBI. Phenytoin has been the only recommended antiepileptic drug (AED) for seizure prophylaxis; however, seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08064f6e62358b2893bcf1e54909317
https://pubmed.ncbi.nlm.nih.gov/27395404
https://pubmed.ncbi.nlm.nih.gov/27395404
Autor:
Xin Xu, Yong Yang, Yan Xiong, Yanke Zhang, Binglin Zhu, Xuefeng Wang, Wei Wang, Fangshuo Zheng
Publikováno v:
Biochemical and biophysical research communications. 478(1)
Glypican-4 (Gpc4) has been found to play an important role in enhancing miniature excitatory postsynaptic currents (mEPSCs). But, the relationship between Gpc4 and epilepsy is still a mystery. In this study, we investigated the expression patterns of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937c103408597d29de1af926ddcd0780
https://pubmed.ncbi.nlm.nih.gov/27425250
https://pubmed.ncbi.nlm.nih.gov/27425250