Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Fangqiong, Hu"'
Autor:
Bin Li, Tao Ding, Haoyi Chen, Changwei Li, Bo Chen, Xing Xu, Ping Huang, Fangqiong Hu, Lei Guo
Publikováno v:
Bone & Joint Research, Vol 12, Iss 1, Pp 33-45 (2023)
AimsCircular RNA (circRNA) is involved in the regulation of articular cartilage degeneration induced by inflammatory factors or oxidative stress. In a previous study, we found that the expression of circStrn3 was significantly reduced in chondrocytes
Externí odkaz:
https://doaj.org/article/bdbba181317c4b749330fd7dc729645d
Autor:
Zhuochao Liu, Hongyi Wang, Chuanzhen Hu, Chuanlong Wu, Jun Wang, Fangqiong Hu, Yucheng Fu, Junxiang Wen, Weibin Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract In this study, we identified the multifaceted effects of atezolizumab, a specific monoclonal antibody against PD-L1, in tumor suppression except for restoring antitumor immunity, and investigated the promising ways to improve its efficacy. A
Externí odkaz:
https://doaj.org/article/db65ee44e4924deaa2fd223ce9a28d2d
Autor:
Zhuochao Liu, Changwei Li, Ping Huang, Fangqiong Hu, Min Jiang, Xing Xu, Bin Li, Lianfu Deng, Tianwen Ye, Lei Guo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tumor necrosis factor-alpha (TNF-α) promotes osteoclasts differentiation to enhance bone resorption and inhibits osteoblasts differentiation to impair bone formation, which plays a central role in the development of postmenopausal osteoporosis (PMOP
Externí odkaz:
https://doaj.org/article/17111a09b948416bb9be9b83bf7871a0
Autor:
Zhuochao Liu, Zhiyong Zheng, Jin Qi, Jun Wang, Qi Zhou, Fangqiong Hu, Jing Liang, Changwei Li, Weibin Zhang, Xingkai Zhang
Publikováno v:
Journal of Biological Engineering, Vol 12, Iss 1, Pp 1-15 (2018)
Abstract Background Cell-based therapy by transplantation of nucleus pulposus (NP) progenitor/notochordal cells has been proposed as a promising way to halt and reverse the progression of disc degeneration. Although some studies have provided a broad
Externí odkaz:
https://doaj.org/article/2ada085b6fb2498eb7ad327a52e48b87
Autor:
Hongyi, Wang, Zhuochao, Liu, Jun, Wang, Fangqiong, Hu, Qi, Zhou, Li, Wei, Qiyuan, Bao, Jizhuang, Wang, Jing, Liang, Zhihong, Liu, Weibin, Zhang
Publikováno v:
Frontiers of Medicine. 16:883-895
Metastasis and drug resistance are the leading causes of poor prognosis in patients with osteosarcoma. Identifying the relevant factors that drive metastasis and drug resistance is the key to improving the therapeutic outcome of osteosarcoma. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebd77e28f47dd5373bd962413b53fb9
https://doi.org/10.1007/s11684-022-0919-0
https://doi.org/10.1007/s11684-022-0919-0
Autor:
Jizhuang, Wang, Fangqiong, Hu, Pei, Yu, Jun, Wang, Zhuochao, Liu, Qiyuan, Bao, Weibin, Zhang, Junxiang, Wen
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Although undergoing conventional chemotherapy significantly improves the prognosis of Osteosarcoma, chemoresistance and failure of therapy is still a significant challenge. Furthermore, conventional chemotherapy, like doxorubicin, would upregulate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8368599948201f0f94c0b1d373b0515d
https://doi.org/10.1007/s00432-022-04458-4
https://doi.org/10.1007/s00432-022-04458-4
Purpose: Although undergoing conventional chemotherapy significantly improves the prognosis of osteosarcoma, chemoresistance and failure of therapy is still a significant challenge. Furthermore, conventional chemotherapy, like doxorubicin, would upre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d4bde35b8ae95b5e59116cc353340db
https://doi.org/10.21203/rs.3.rs-1978860/v1
https://doi.org/10.21203/rs.3.rs-1978860/v1
Autor:
Bin Li, Fei Wang, Fangqiong Hu, Tao Ding, Ping Huang, Xing Xu, Jing Liang, Changwei Li, Qi Zhou, Min Lu, Lianfu Deng, Lei Guo, Wenguo Cui
Publikováno v:
NPG Asia Materials. 14
Sustained and controllable local gene therapy is a potential method for treating osteoarthritis (OA) through the delivery of therapeutic microRNAs (miRNAs) to targeted cells. However, direct injection of crude miRNAs for local gene therapy is limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::919c3b353e34ae57ddb2cfc8e4f90dcf
https://doi.org/10.1038/s41427-021-00351-7
https://doi.org/10.1038/s41427-021-00351-7
Publikováno v:
Cancer science. 113(2)
Thrombospondin-1 (TSP1) is generally assumed to suppress the growth of osteosarcoma through inhibiting angiogenesis; however, it is unclear whether TSP1 could affect the antitumor immunity against osteosarcoma. We aimed to explore the immune-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eb1e0e278af61bbc801ecee4520039
https://pubmed.ncbi.nlm.nih.gov/34927311
https://pubmed.ncbi.nlm.nih.gov/34927311
Autor:
Tao Ding, Niandong Qian, Lei Guo, Kaizhe Chen, Fangqiong Hu, Bo Chen, Qi Zhou, Lianfu Deng, Xing Xu, Bin Li, Tianwen Ye, Ping Huang
Publikováno v:
Journal of Cellular and Molecular Medicine
Osteoarthritis (OA) is one of the most frequent chronic joint diseases with the increasing life expectancy. The main characteristics of the disease are loss of articular cartilage, subchondral bone sclerosis and synovium inflammation. Physical measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317897cf74d12d1a2f74e03a5f5d183b
https://pubmed.ncbi.nlm.nih.gov/33939310
https://pubmed.ncbi.nlm.nih.gov/33939310