Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Fanglu Huang"'
Autor:
Anastasiia Gusach, Yang Lee, Armin Nikpour Khoshgrudi, Elizaveta Mukhaleva, Ning Ma, Eline J. Koers, Qingchao Chen, Patricia C. Edwards, Fanglu Huang, Jonathan Kim, Filippo Mancia, Dmitry B. Veprintsev, Nagarajan Vaidehi, Simone N. Weyand, Christopher G. Tate
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract There are two main families of G protein-coupled receptors that detect odours in humans, the odorant receptors (ORs) and the trace amine-associated receptors (TAARs). Their amino acid sequences are distinct, with the TAARs being most similar
Externí odkaz:
https://doaj.org/article/652fff5f256d4ddc952071804619e0c2
Efophylins A and B, Two C2-Asymmetric Macrodiolide Immunosuppressants from Streptomyces malaysiensis
Publikováno v:
Journal of Natural Products. 84:1579-1586
Genomics-inspired isolation led to the identification of two new natural congeneric C2-asymmetric macrodiolide immunosuppressants, named efophylins A (1) and B (2), from Streptomyces malaysiensis DSM 4137. Their structures were elucidated by spectros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17a36d45f75f1c254b5b90f296e8be0e
https://doi.org/10.1021/acs.jnatprod.1c00118
https://doi.org/10.1021/acs.jnatprod.1c00118
Autor:
Fanglu Huang, Fabian Grabenhorst
Animals make adaptive food choices to acquire nutrients that are essential for survival. In reinforcement learning (RL), animals choose by assigning values to options and update these values with new experiences. This framework has been instrumental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ae598f3a6979d7c085511fa71bd6aec
https://doi.org/10.1101/2021.06.20.448600
https://doi.org/10.1101/2021.06.20.448600
Autor:
Xinyun Jian, Peter F. Leadlay, Fanglu Huang, Junhong Guo, Jiahai Zhou, Marcio Vinicius Bertacine Dias, Zixin Deng, Yuan Li, Yuhui Sun, Priscila dos Santos Bury, Anna Reva, Chuan Huang, Finian J. Leeper, Sicong Li, Guo Sun
Gentamicin is an important aminoglycoside antibiotic used for treatment of infections caused by Gram-negative bacteria. Although most of the biosynthetic pathway of gentamicin has been elucidated, a remaining intriguing question is how the intermedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1392366e7d22aa2ad68fb3d50af392d8
https://doi.org/10.21203/rs.3.rs-538562/v1
https://doi.org/10.21203/rs.3.rs-538562/v1
Publikováno v:
Journal of natural products. 84(5)
Genomics-inspired isolation led to the identification of two new natural congeneric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edce000009cb84cbec5acacc67fb5813
https://pubmed.ncbi.nlm.nih.gov/33973788
https://pubmed.ncbi.nlm.nih.gov/33973788
Autor:
Sicong Li, Priscila Dos Santos Bury, Fanglu Huang, Junhong Guo, Guo Sun, Anna Reva, Chuan Huang, Xinyun Jian, Yuan Li, Jiahai Zhou, Zixin Deng, Finian J. Leeper, Peter F. Leadlay, Marcio V. B. Dias, Yuhui Sun
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gentamicin is an important aminoglycoside antibiotic used for treatment of infections caused by Gram-negative bacteria. Although most of the biosynthetic pathways of gentamicin have been elucidated, a remaining intriguing question is how the intermed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f0290842905535e56133a6424bd3b6
Autor:
Maurício Temotheo Tavares, Natalia Cerrone de Araújo, Roberto Parise-Filho, Marcio Vinicius Bertacine Dias, Peter F. Leadlay, Priscila dos Santos Bury, Fanglu Huang
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gentamicins are clinically relevant aminoglycoside antibiotics produced by several Micromonospora species. Gentamicins are highly methylated and functionalized molecules, and their biosynthesis include glycosyltransferases, dehydratase/oxidoreductase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b448c388ef84b210315bd1553f005c82
Autor:
Peter F. Leadlay, Marcio Vinicius Bertacine Dias, Fanglu Huang, Priscila dos Santos Bury, Yuhui Sun, Sicong Li
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Gentamicins are heavily methylated, clinically valuable pseudotrisaccharide antibiotics produced by Micromonospora echinospora. GenN has been characterized as an S-adenosyl-l-methionine-dependent methyltransferase with low sequence similarity to othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445311fd905863cd4647d90b7772dd10
Autor:
Andrew W. Truman, Fanglu Huang, Shu Wu, Tom L. Blundell, Marcio Vinicius Bertacine Dias, Jonathan B. Spencer
Publikováno v:
Chemistry & Biology. 16(6):676-685
SummaryGlycodiversification, an invaluable tool for generating biochemical diversity, can be catalyzed by glycosyltransferases, which attach activated sugar “donors” onto “acceptor” molecules. However, many glycosyltransferases can tolerate o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe013bc277573122991184ccfc3743c9
Autor:
Fanglu Huang, Lijiang Song, Judith Havemann, Peter F. Leadlay, Helen K. Potter, Jack A. Connolly, Ina Wilkening, James S. Parascandolo, Elena Riva, Manuela Tosin
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
Angewandte Chemie (Weinheim an Der Bergstrasse, Germany)
Chemical probes capable of reacting with KS (ketosynthase)‐bound biosynthetic intermediates were utilized for the investigation of the model type I iterative polyketide synthase 6‐methylsalicylic acid synthase (6‐MSAS) in vivo and in vitro. Fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f59d76af0e35ad107808ab3d995bffc
https://pubmed.ncbi.nlm.nih.gov/26833898
https://pubmed.ncbi.nlm.nih.gov/26833898