Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Fanglin, Guan"'
Autor:
Yang Chen, Yuhao Gu, Bianbian Wang, Anqi Wei, Nan Dong, Yong Jiang, Xiaoying Liu, Li Zhu, Feng Zhu, Tao Tan, Zexin Jing, Fenghan Mao, Yichi Zhang, Jingyu Yao, Yuxin Yang, Hongyan Wang, Hao Wu, Hua Li, Chaowen Zheng, Xueting Duan, Jingxiao Huo, Xuanang Wu, Shaoqin Hu, Anran Zhao, Ziyang Li, Xu Cheng, Yuhao Qin, Qian Song, Shuqin Zhan, Qiumin Qu, Fanglin Guan, Huadong Xu, Xinjiang Kang, Changhe Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Schizophrenia is a severe neuropsychiatric disease, but the initiation mechanisms are unclear. Although antipsychotics are effective against positive symptoms, therapeutic interventions for negative symptoms are limited due to the lack of pa
Externí odkaz:
https://doaj.org/article/c83b7c184592449bb47292d9bf4edfdb
Autor:
Miao Li, Ke Chen, Yuqi Chen, Lei Zhang, Yipeng Cui, Fengxu Xiao, Zhenting Liu, Wen Zhang, Jue jiang, Qi Zhou, Jiangwei Yan, Yu Sun, Fanglin Guan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Hashimoto's thyroiditis (HT) is an autoimmune disorder with unclear molecular mechanisms. While current diagnosis is well-established, understanding of the gut-thyroid axis in HT remains limited. This study aimed to uncover novel
Externí odkaz:
https://doaj.org/article/be86c7b3e87444cb8f7b290523aa01c0
Autor:
Long-Biao Cui, Xian-Yang Wang, Yu-Fei Fu, Xiao-Fan Liu, Yongbin Wei, Shu-Wan Zhao, Yue-Wen Gu, Jing-Wen Fan, Wen-Jun Wu, Hengfen Gong, Bochao Danae Lin, Hong Yin, Fanglin Guan, Xiao Chang
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Inflammation has been implicated in the pathology of schizophrenia and may cause neuronal cell death and dendrite loss. Neuroimaging studies have highlighted longitudinal brain structural changes in patients with schizophrenia, ye
Externí odkaz:
https://doaj.org/article/cabac8ded8364f92bfcd27370bda4553
Autor:
Zhao Jiang, Tianxiao Zhang, Wei Han, Jing Xiao, Wenpei Zhang, Xiaochen Wang, Jianing Liu, Ying Yang, Congying Yang, Fanglin Guan, Tao Li, John P. Rice
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Methamphetamine use disorder (MUD) has become a global problem due to the highly addictive nature of methamphetamine. Earlier research have demonstrated that PROK2 functions as a compensatory and protective response against neurotoxic str
Externí odkaz:
https://doaj.org/article/f319a7ec5b6b48aea17156d7c8edfc08
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/c9307f84d6a94d5098182d986d0f2a5a
Autor:
Jiewei Liu, Shiwu Li, Xiaoyan Li, Wenqiang Li, Yongfeng Yang, Suqin Guo, Luxian Lv, Xiao Xiao, Yong-Gang Yao, Fanglin Guan, Ming Li, Xiong-Jian Luo
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Over 200 schizophrenia risk loci have been identified by genome-wide association studies (GWASs). However, the majority of risk loci were identified in populations of European ancestry (EUR), potentially missing important biologic
Externí odkaz:
https://doaj.org/article/fc9fe80d0f57443b8c33029d9308ee96
Autor:
Suqin Guo, Jiewei Liu, Wenqiang Li, Yongfeng Yang, Luxian Lv, Xiao Xiao, Ming Li, Fanglin Guan, Xiong-Jian Luo
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Early onset schizophrenia (EOS, defined as first onset of schizophrenia before age 18) is a rare form of schizophrenia (SCZ). Though genome-wide association studies (GWASs) have identified multiple risk variants for SCZ, most of the cases in
Externí odkaz:
https://doaj.org/article/61817dd0ad464fbc9ebe1a9a12623dec
Autor:
Jing Xiao, Yitian Ma, Xiaochen Wang, Changqing Wang, Miao Li, Haobiao Liu, Wei Han, Huiying Wang, Wenpei Zhang, Hang Wei, Longrui Zhao, Tianxiao Zhang, Huali Lin, Fanglin Guan
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
ObjectivesMethamphetamine (METH) is a central nervous psychostimulant and one of the most frequently used illicit drugs. Numerous genetic loci that influence complex traits, including alcohol abuse, have been discovered; however, genetic analyses for
Externí odkaz:
https://doaj.org/article/e22c4022e9b445eeb68d2a6b1f4283be
Autor:
Wenqiang Li, Chu-Yi Zhang, Jiewei Liu, Fanglin Guan, Minglong Shao, Luwen Zhang, Qing Liu, Yongfeng Yang, Xi Su, Yan Zhang, Xiao Xiao, Xiong-Jian Luo, Ming Li, Luxian Lv
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Shared psychopathological features and mechanisms have been observed between schizophrenia (SZ) and bipolar disorder (BD), but their common risk genes and full genetic architectures remain to be fully characterized. The genome-wide associ
Externí odkaz:
https://doaj.org/article/1f34c45d803f4a508101e2f5960a4649
Autor:
Shiqiang Cheng, Fanglin Guan, Mei Ma, Lu Zhang, Bolun Cheng, Xin Qi, Chujun Liang, Ping Li, Om Prakash Kafle, Yan Wen, Feng Zhang
Publikováno v:
European Psychiatry, Vol 63 (2020)
AbstractBackground.Psychiatric disorders are a group of complex psychological syndromes with high prevalence. Recent studies observed associations between altered plasma proteins and psychiatric disorders. This study aims to systematically explore th
Externí odkaz:
https://doaj.org/article/0431554c747646fbbed540f7808c98cd