Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Fanghui Ren"'
Autor:
Demi van der Horst, Naziia Kurmasheva, Mikkel H. S. Marqvorsen, Sonia Assil, Anna H. F. Rahimic, Christoph F. Kollmann, Leandro Silva da Costa, Qi Wu, Jian Zhao, Eleonora Cesari, Marie B. Iversen, Fanghui Ren, Trine I. Jensen, Ryo Narita, Vivien R. Schack, Bao-cun Zhang, Rasmus O. Bak, Claudio Sette, Robert A. Fenton, Jacob G. Mikkelsen, Søren R. Paludan, David Olagnier
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract DNA is a danger signal sensed by cGAS to engage signaling through STING to activate innate immune functions. The best-studied downstream responses to STING activation include expression of type I interferon and inflammatory genes, but STING
Externí odkaz:
https://doaj.org/article/0db80e2a99374afa9c136a61eb6b74e2
Autor:
Azadeh Reyahi, Marie Studahl, Morten K. Skouboe, Stefanie Fruhwürth, Ryo Narita, Fanghui Ren, Moa Bjerhem Viklund, Marie B. Iversen, Mette Christiansen, Alexandra Svensson, Trine H. Mogensen, Kristina Eriksson, Søren R. Paludan
Publikováno v:
JCI Insight, Vol 8, Iss 21 (2023)
The mechanisms underlying susceptibility to recurrent herpes simplex virus type 2 (HSV-2) meningitis remain incompletely understood. In a patient experiencing multiple episodes of HSV-2 meningitis, we identified a monoallelic variant in the IKBKE gen
Externí odkaz:
https://doaj.org/article/1ad2f5e9dd7e402595f5a7e6d67ef040
Autor:
Jing Yang, Fanghui Ren, Xinyuan Chong, Donglei Fan, Swapnajit Chakravarty, Zheng Wang, Ray T. Chen, Alan X. Wang
Publikováno v:
Photonics, Vol 1, Iss 4, Pp 380-389 (2014)
We designed and fabricated guided-mode resonance (GMR) gratings on indium-tin-oxide (ITO) thin film to generate a significantly enhanced local electric field for surface-enhanced Raman scattering (SERS) spectroscopy. Ag nanoparticles (NPs) were self-
Externí odkaz:
https://doaj.org/article/96d5c821fab047ed8600eb0be3a114bb
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159498 (2016)
Previous studies have demonstrated that microRNA-132 plays a vital part in and is actively associated with several cancers, with its tumor-suppressive role in hepatocellular carcinoma confirmed. The current study employed multiple bioinformatics tech
Externí odkaz:
https://doaj.org/article/d67faa7030df4a06959f6d696bfcb5cd
Autor:
Fanghui Ren, Ruixue Tang, Xin Zhang, Wickramaarachchi Mihiranganee Madushi, Dianzhong Luo, Yiwu Dang, Zuyun Li, Kanglai Wei, Gang Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135544 (2015)
Matrix metalloproteinases (MMPs) are regarded to be relevant to the prognosis of breast cancer. Numerous studies have confirmed the association between MMPs and tumor growth, invasion and metastasis in breast cancer. However, their prognostic values
Externí odkaz:
https://doaj.org/article/ce9d1824cb2845d6bbbfaaf07669ed56
Autor:
Martin R. Jakobsen, Jean-Simon Diallo, Anne Louise Hansen, Taha Azad, Luc A. Sabourin, David Jacobs, Manja Idorn, Geneviève Laroche, Julien van Grevenynghe, Renée M. van der Sluis, Glib Maznyi, Jean Seguin, Fanghui Ren, Daniele Di Carlo, Rozanne Arulanandam, Ragunath Singaravelu, Kathy Fu, David Olagnier, Tommy Alain, Christian K. Holm, Søren R. Paludan, John C. Bell, Marceline Côté, John Hiscott, Demi van der Horst, Naziia Kurmasheva, Lena Cassin, Enrico Palermo, Madalina E. Carter-Timofte, Zaid Taha
Publikováno v:
ACS Infectious Diseases
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
Carter-Timofte, M E, Arulanandam, R, Kurmasheva, N, Fu, K, Laroche, G, Taha, Z, Van Der Horst, D, Cassin, L, Van Der Sluis, R M, Palermo, E, Di Carlo, D, Jacobs, D, Maznyi, G, Azad, T, Singaravelu, R, Ren, F, Hansen, A L, Idorn, M, Holm, C K, Jakobsen, M R, Van Grevenynghe, J, Hiscott, J, Paludan, S R, Bell, J C, Seguin, J, Sabourin, L A, Côté, M, Diallo, J S, Alain, T & Olagnier, D 2021, ' Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern ', ACS Infectious Diseases, vol. 7, no. 11, pp. 3034-3051 . https://doi.org/10.1021/acsinfecdis.1c00278
The antimicrobial medication malarone (atovaquone/proguanil) is used as a fixed-dose combination for treating children and adults with uncomplicated malaria or as chemoprophylaxis for preventing malaria in travelers. It is an inexpensive, efficacious
Autor:
Søren R. Paludan, Alon Schneider Hait, Sathya Darmalinggam, Mette Christiansen, Simon Muller Larsen, Jørgen Kjems, Darshana D. Kadekar, Kristina Eriksson, Serge Mostowy, Liviu Ionut Moldovan, Nanna-Sophie Brinck Andersen, Vanessa Sancho-Shimizu, Trine H. Mogensen, Lasse Sommer Kristensen, Isobel Parkes, David Olagnier, Marie Helleberg, Demi van der Horst, Michelle M. Thomsen, Mette Ratzer Freytag, Kristian Alsbjerg Skipper, Stine H. Rahbek, Jacob Giehm Mikkelsen, Christian Brandt, Chiranjeevi Bodda, Fanghui Ren
Publikováno v:
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Brinck Andersen, N-S, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2020, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science Immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/sciimmunol.abc2691
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Andersen, N S B, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2021, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/SCIIMMUNOL.ABC2691
Science Immunology
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Andersen, N S B, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2021, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/SCIIMMUNOL.ABC2691
Science Immunology
Recurrent herpesvirus infections can manifest in different forms of disease, including cold sores, genital herpes, and encephalitis. There is an incomplete understanding of the genetic and immunological factors conferring susceptibility to recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e2d27ad827935f3a3c72318f2fa311
https://pure.au.dk/portal/da/publications/defects-in-lc3b2-and-atg4a-underlie-hsv2-meningitis-and-reveal-a-critical-role-for-autophagy-in-antiviral-defense-in-humans(660e28c6-e88f-4155-8813-69748e66d63d).html
https://pure.au.dk/portal/da/publications/defects-in-lc3b2-and-atg4a-underlie-hsv2-meningitis-and-reveal-a-critical-role-for-autophagy-in-antiviral-defense-in-humans(660e28c6-e88f-4155-8813-69748e66d63d).html
Autor:
Alon Schneider, Hait, David, Olagnier, Vanessa, Sancho-Shimizu, Kristian Alsbjerg, Skipper, Marie, Helleberg, Simon Muller, Larsen, Chiranjeevi, Bodda, Liviu Ionut, Moldovan, Fanghui, Ren, Nanna-Sophie, Brinck Andersen, Michelle M, Thomsen, Mette Ratzer, Freytag, Sathya, Darmalinggam, Isobel, Parkes, Darshana D, Kadekar, Stine Hess, Rahbek, Demi, van der Horst, Lasse Sommer, Kristensen, Kristina, Eriksson, Jørgen, Kjems, Serge, Mostowy, Mette, Christiansen, Jacob Giehm, Mikkelsen, Christian Thomas, Brandt, Søren R, Paludan, Trine H, Mogensen
Publikováno v:
Sci Immunol
Recurrent herpesvirus infections can lead to numerous forms of diseases ranging from cold sore and genital herpes to encephalitis. Currently, there is an incomplete understanding of the genetic and immunological factors conferring susceptibility to r
Autor:
Hong Yang, Hai-Wei Liang, Fanghui Ren, Gang Chen, Zhen-Bo Feng, Yi-Wu Dang, Rong-Quan He, Jing-ning Lu, Xinggu Lin, Dian-Zhong Luo
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer
BMC Cancer
Background Currently, some studies have demonstrated that miR-34a could serve as a suppressor of several cancers including hepatocellular carcinoma (HCC). Previously, we discovered that miR-34a was downregulated in HCC and involved in the tumorigenes
Publikováno v:
FEBS Open Bio
Our previous research has demonstrated that miR‐146a‐5p is down‐regulated in hepatocellular carcinoma (HCC) and might play a tumor‐suppressive role. In this study, we sought to validate the decreased expression with a larger cohort and to exp