Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Fanghua Ye"'
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27305- (2024)
Background: Limited research has been conducted on the impact of rituximab on immune function and the incidence of side effects in children undergoing combination chemotherapy for aggressive mature B-cell lymphoma/leukemia. Methods: Clinical data fro
Externí odkaz:
https://doaj.org/article/4754c31ca49b4a87832e0bae6c2b07df
Antileukemic effect of venetoclax and hypomethylating agents via caspase-3/GSDME-mediated pyroptosis
Autor:
Fanghua Ye, Wen Zhang, Chenying Fan, Jiajia Dong, Min Peng, Wenjun Deng, Hui Zhang, Liangchun Yang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background The identifying of B-cell lymphoma 2 (Bcl-2) as a therapeutic target has led to a paradigm shift in acute myeloid leukemia (AML) treatment. Pyroptosis is a novel antitumor therapeutic mechanism due to its cytotoxic and immunogenic
Externí odkaz:
https://doaj.org/article/f9554e5b58a241669e48f9c5aea0ebcc
Autor:
Lanlan Tang, Yan Yu, Wenjun Deng, Jiao Liu, Yichun Wang, Fanghua Ye, Rui Kang, Daolin Tang, Qingnan He
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108393- (2023)
Summary: Ferroptosis is a type of regulated cell death characterized by lipid peroxidation and subsequent damage to the plasma membrane. Here, we report a ferroptosis resistance mechanism involving the upregulation of TXNDC12, a thioredoxin domain-co
Externí odkaz:
https://doaj.org/article/9301e413c5cf42c5a77f5365b64f8b24
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
PurposeMyeloid sarcoma (MS) is a rare extramedullary mass with myeloid expression, which is easy to be missed and misdiagnosed, especially in the pediatric population. We analyze the clinicopathological characteristics, immunophenotypic, cytogenetic,
Externí odkaz:
https://doaj.org/article/64fde4f299c74e8084c8f1baf50465ab
Autor:
Fanghua Ye, Wen Zhang, Jiajia Dong, Min Peng, Chenying Fan, Wenjun Deng, Hui Zhang, Liangchun Yang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare congenital immune deficiency characterized by susceptibility to weakly virulent mycobacteria. Loss-of-function (LOF) mutation of signal transducer and activator of transcription 1 (S
Externí odkaz:
https://doaj.org/article/d5838b3aeca44cbaae29589b24e3fc31
Autor:
Wen Zhang, Dong Li, Nan Pang, Li Jiang, Baomin Li, Fanghua Ye, Fang He, Shimeng Chen, Fangyun Liu, Jing Peng, Jinghua Yin, Fei Yin
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ObjectiveAlthough many unexplained intellectual disability/global developmental delay (ID/GDD) individuals have benefited from the excellent detection yield of copy number variations and next-generation sequencing testing, many individuals still who
Externí odkaz:
https://doaj.org/article/6f5c8f444d9e48dc9d62bc00d482e0b5
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
CSNK2B has recently been identified as the causative gene for Poirier–Bienvenu neurodevelopmental syndrome (POBINDS). POBINDS is a rare neurodevelopmental disorder characterized by early-onset epilepsy, developmental delay, hypotonia, and dysmorphi
Externí odkaz:
https://doaj.org/article/cab51a5f2a5b4451b8beb42915926225
Autor:
Wen Zhang, Fanghua Ye, Nan Pang, Miriam Kessi, Juan Xiong, Shimeng Chen, Jing Peng, Li Yang, Fei Yin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glutamate-induced excitotoxicity is a pathological basis of many acute/chronic neurodegenerative diseases. Sarco/endoplasmic reticulum Ca2+-ATPase (SERCA2b) is a membrane-embedded P-type ATPase pump that manages the translocation of calcium ions (Ca2
Externí odkaz:
https://doaj.org/article/278d420491854d62a1284947746997e2
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background Sodium/iodide symporter (NIS)-mediated iodide uptake plays an important physiological role in regulating thyroid gland function, as well as in diagnosing and treating Graves’ disease and thyroid cancer. High-mobility group box 1
Externí odkaz:
https://doaj.org/article/f229fc3e3c5544baad0a9cf38e679c44
Publikováno v:
IEEE Access, Vol 6, Pp 47240-47257 (2018)
Identifying a small subset of influential individuals on social networks can bring great benefits for many practical applications like viral marketing. This issue is typically formulated as the influence maximization problem. As a fundamental researc
Externí odkaz:
https://doaj.org/article/4d887649705944159781d71cf62bd4eb