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Akademický článek

Monocyte HLA‐DR level on admission predicting in‐hospital mortality rate in exertional heatstroke: A 12‐year retrospective study

Autor: Fanfan Wang, Fanghe Gong, Xuezhi Shi, Jiale Yang, Jing Qian, Lulu Wan, Huasheng Tong

Publikováno v: Immunity, Inflammation and Disease, Vol 12, Iss 4, Pp n/a-n/a (2024)

Abstract Background Exertional heatstroke (EHS), a fatal illness, pronounces multiple organ dysfunction syndrome (MODS) and high mortality rate. Currently, no ideal factor prognoses EHS. Decreased monocyte human leukocyte‐DR antigen (mHLA‐DR) has

Externí odkaz: https://doaj.org/article/1d929cafbef84dcdbbad4f1ec4ee3179

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Akademický článek

Ferroptosis and mitochondrial dysfunction in acute central nervous system injury

Autor: Wenxue Dong, Fanghe Gong, Yu Zhao, Hongmin Bai, Ruixin Yang

Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)

Acute central nervous system injuries (ACNSI), encompassing traumatic brain injury (TBI), non-traumatic brain injury like stroke and encephalomeningitis, as well as spinal cord injuries, are linked to significant rates of disability and mortality glo

Externí odkaz: https://doaj.org/article/db2e8e710ec44374be2ee782d4b1f2df

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Akademický článek

A nomogram based on lymphocyte percentage for predicting hospital mortality in exertional heatstroke patients: a 13-year retrospective study.

Autor: Jiale Yang^1,2, Fanghe Gong³, Xuezhi Shi², Fanfan Wang², Jing Qian^1,2, Lulu Wan^1,2, Yi Chen⁴, Huaisheng Chen⁵, Huasheng Tong^1,2 fimmuths@163.com

Publikováno v: World Journal of Emergency Medicine. 2023, Vol. 14 Issue 6, p434-441. 8p.

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Targeted inhibition of HDAC8 increases the doxorubicin sensitivity of neuroblastoma cells via up regulation of miR-137

Autor: Hongmin Bai, Gang Zhao, Weimin Wang, Huan Yang, Tiandong Li, Fanghe Gong, Jinchong Wen, Guoliang Wang

Publikováno v: European journal of pharmacology. 802

Histone deacetylases (HDACs) have been suggested to be potential therapeutic targets for cancer treatment. Recent studies revealed that HDAC8 expression was associated with poor prognostic markers and poor overall survival rate of neuroblastoma (NB).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c360c1a62c212bf84fd7dcf0beea81
https://pubmed.ncbi.nlm.nih.gov/28223126

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14-3-3β regulates the proliferation of glioma cells through the GSK3β/β-catenin signaling pathway

Autor: Fanghe Gong, Guoliang Wang, Tiandong Li, Hongmin Bai, Jing Ye, Weimin Wang

Publikováno v: Oncology Reports. 30:2976-2982

We previously demonstrated that 14-3-3β is overexpressed in astrocytomas; however, the underlying mechanisms are poorly understood. Based on the reported multiple functions of 14-3-3β, we hypothesized that it interacts with glycogen synthase kinase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283941fbaf55c9858f6d226e00f10b2c
https://doi.org/10.3892/or.2013.2740

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Mutation of isocitrate dehydrogenase 1 induces glioma cell proliferation via nuclear factor-κB activation in a hypoxia-inducible factor 1-α dependent manner

Autor: GuoLiang Wang, Jian Lin, Furong Chen, QunYing Yang, FangHe Gong, Ke Sai

Publikováno v: Molecular medicine reports. 9(5)

Recently, mutations of the isocitrate dehydrogenase (IDH) 1 gene, which specifically occur in the majority of low-grade and secondary high-grade gliomas, have drawn particular attention of neuro-oncologists. Mutations of the IDH1 gene have been propo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37537936aeaf74440631769e3c90ad0b
https://pubmed.ncbi.nlm.nih.gov/24626950

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