Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fangcheng Luo"'
Autor:
Mei Jing, Yun Cen, Fangfang Gao, Ting Wang, Jinxin Jiang, Qianqian Jian, Liangmiao Wu, Baojian Guo, Fangcheng Luo, Gaoxiao Zhang, Ying Wang, Lipeng Xu, Zaijun Zhang, Yewei Sun, Yuqiang Wang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD. Our previous studies demonstrated that tetramethylp
Externí odkaz:
https://doaj.org/article/7beeec539874415388322609713d303f
Autor:
Yifan Han, Zaijun Zhang, Yuqiang Wang, Baojian Guo, Shengquan Hu, Zheng Liu, Jiajun Wang, Liangmiao Wu, Guozhen Cui, Yewei Sun, Fangcheng Luo, Ziyan Liu, Shinghung Mak, Gaoxiao Zhang
Publikováno v:
ACS Chemical Neuroscience. 11:314-327
We have previously designed and synthesized a series of novel memantine nitrates, and some of them have shown neuroprotective effects; however, the detailed mechanisms remain unknown. In this study, we demonstrated that MN-12, one of the memantine ni
Autor:
Baojian Guo, Mei Jing, Lipeng Xu, Yuqiang Wang, Gaoxiao Zhang, Yewei Sun, Jinxin Jiang, Qianqian Jian, Fangfang Gao, Yun Cen, Ting Wang, Ying Wang, Zaijun Zhang, Liangmiao Wu, Fangcheng Luo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD. Our previous studies demonstrated that tetramethylp
Autor:
Zheng Liu, Ling Zha, Yuqiang Wang, Gaoxiao Zhang, Zhixiang Zhang, Liangmiao Wu, Fangcheng Luo, Fangfang Gao, Guoqing Xie, Yewei Sun, Zaijun Zhang, Guangying Chen
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 77(5)
Pulmonary arterial hypertension (PAH) is a rare, progressive pulmonary vascular disease with limited therapeutic options. Pulmonary circulation resistance, pulmonary vascular remodeling, and over-activated NMDARs (N-methyl-d-aspartate receptors) play
Autor:
Shinghung, Mak, Zheng, Liu, Liangmiao, Wu, Baojian, Guo, Fangcheng, Luo, Ziyan, Liu, Shengquan, Hu, Jiajun, Wang, Guozhen, Cui, Yewei, Sun, Yuqiang, Wang, Gaoxiao, Zhang, Yifan, Han, Zaijun, Zhang
Publikováno v:
ACS chemical neuroscience. 11(3)
We have previously designed and synthesized a series of novel memantine nitrates, and some of them have shown neuroprotective effects; however, the detailed mechanisms remain unknown. In this study, we demonstrated that MN-12, one of the memantine ni
Autor:
Yuqiang Wang, Yifan Han, Zhixiang Zhang, Zheng Liu, Gaoxiao Zhang, Yewei Sun, Xifei Yang, Shupeng Li, Shinghung Mak, Jun Ju, Fangcheng Luo, Zaijun Zhang, Ning Li, Baojian Guo, Liangmiao Wu, Zeyu Zhu, Qiang Zhou
Publikováno v:
Br J Pharmacol
Background and purpose Cerebral vasospasm and neuronal apoptosis after subarachnoid haemorrhage (SAH) is the major cause of morbidity and mortality in SAH patients. So far, single-target agents have not prevented its occurrence. Memantine, a non-comp
Autor:
Xiaoling Qiu, Daping Xu, Guozhen Cui, Yifan Han, Gaoxiao Zhang, Baojian Guo, Zheng Liu, Yuqiang Wang, Shinghung Mak, Shengquan Hu, Fangcheng Luo, Yewei Sun, Jiajun Wang, Zaijun Zhang
Publikováno v:
Chemico-biological interactions. 325
Overactivation of N-methyl-D-aspartate (NMDA) receptors has been associated with neurodegenerative disorders such as Alzheimer's disease (AD), cerebral vascular disorders and amyotrophic lateral sclerosis (ALS). We have previously designed and synthe
Autor:
Tony Chunglit Choi, Yuqiang Wang, Edmond Dik Lung Ma, Baojian Guo, Shinghung Mak, Yifan Han, Fangcheng Luo, Guozhen Cui, Chengyou Zheng, Shengquan Hu, Simon Ming-Yuen Lee, Hongyu Wang, Xifei Yang, Haitao Li, Wei Cui, Zaijun Zhang
Publikováno v:
Neuropharmacology. 126
We have previously demonstrated the unexpected neuroprotection of the anti-cancer agent SU4312 in cellular models associated with Parkinson's disease (PD). However, the precise mechanisms underlying its neuroprotection are still unknown, and the effe
Publikováno v:
Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry. 30:271-279
Crystalline yttrium carbonate, Y2(CO3)3·2.79H2O, was synthesized using ammonium bicarbonate as precipitant. The X ray diffraction data were indexed in the triclinic system with cell parameters a = 19. 076A, b = 22. 312A, c = 7. 823A, α = 94. 493°,
Publikováno v:
Journal of Crystal Growth. 206:88-92
The precipitation of cerous carbonate was studied using ammonium bicarbonate as precipitant. The good crystalline cerous carbonate was prepared by aging it in a suitable condition. The aging kinetics was investigated using the SEM method. The size an