Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Fangchen Lin"'
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
CAF secreted HGF mediates HNSCC glycolysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ade80e51d638424361baee61930cf2e
https://doi.org/10.1158/0008-5472.22418087
https://doi.org/10.1158/0008-5472.22418087
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
Endogenous expression of bFGF in HNSCC and FGFR in CAFs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258bce787aeb4d37c50e0efe74d7022c
https://doi.org/10.1158/0008-5472.22418084
https://doi.org/10.1158/0008-5472.22418084
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
Despite aggressive therapies, head and neck squamous cell carcinoma (HNSCC) is associated with a less than 50% 5-year survival rate. Late-stage HNSCC frequently consists of up to 80% cancer-associated fibroblasts (CAF). We previously reported that CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4078833939d7f78c92db585c58b93345
https://doi.org/10.1158/0008-5472.c.6510029.v1
https://doi.org/10.1158/0008-5472.c.6510029.v1
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
Legends for all supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0058d681b437a40a8daeaa5dca19d9f9
https://doi.org/10.1158/0008-5472.22418078.v1
https://doi.org/10.1158/0008-5472.22418078.v1
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
Combination of AZD-4547 and PF-02341066 indicates potentiated effect in admixed cultures but not in HNSCC only inoculated tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca00b4715e2de9a79101e13d0e33d76
https://doi.org/10.1158/0008-5472.22418081
https://doi.org/10.1158/0008-5472.22418081
Autor:
Sufi Mary Thomas, Partha Krishnamurthy, Shrikant Anant, Bennett Van Houten, Douglas A. Girod, Terance Ted Tsue, Kiran Kakarala, Yelizaveta Shnayder, Jeffrey Straub, Ossama Tawfik, Hongying Dai, Mackenzie M. Thornton, Lydia Ganaden, Hemantkumar Chavan, Sivapriya Ponnurangam, George Leef, Wade R. Gutierrez, Sumana Dasari, Fangchen Lin, Jonathan Enders, Radhika Joshi, Vikalp Vishwakarma, Jacob New, Dhruv Kumar
HNSCC Cells have Higher Glycolytic Capacity than CAFs and CAFs have Higher Maximal Respiration than HNSCC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44b1b7c528bf47fa10c43117e1ba751
https://doi.org/10.1158/0008-5472.22418090.v1
https://doi.org/10.1158/0008-5472.22418090.v1
Autor:
Radhika Joshi, Lydia Ganaden, Vikalp Vishwakarma, Hongying Dai, Sufi M. Thomas, Douglas A. Girod, Bennett Van Houten, Shrikant Anant, Kiran Kakarala, Partha Krishnamurthy, Sumana Dasari, Mackenzie M. Thornton, Jonathan Enders, Yelizaveta Shnayder, Jeffrey Straub, Jacob New, Dhruv Kumar, George Leef, Hemantkumar Chavan, Wade R. Gutierrez, Terance T. Tsue, Ossama Tawfik, Fangchen Lin, Sivapriya Ponnurangam
Publikováno v:
Cancer research. 78(14)
Despite aggressive therapies, head and neck squamous cell carcinoma (HNSCC) is associated with a less than 50% 5-year survival rate. Late-stage HNSCC frequently consists of up to 80% cancer-associated fibroblasts (CAF). We previously reported that CA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5eb4b28b1292bc55ea8f7f4b864d4e
https://pubmed.ncbi.nlm.nih.gov/29769197
https://pubmed.ncbi.nlm.nih.gov/29769197
Autor:
Fangchen Lin, Radhika Joshi, Simon C. Watkins, Sufi M. Thomas, Huifang Shi, Stephen H. Thorne, Sumana Dasari, Joseph S. Bednash, Sarah E Wheeler
Publikováno v:
Head & Neck. 36:385-392
Background Head and neck squamous cell carcinoma (HNSCC) has had little improvement in mortality rates in decades. A clearer understanding of the HNSCC tumor microenvironment will aid in finding more effective targeted therapies for this disease. Tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0986086e9aa543c4074ee79020f355e1
https://doi.org/10.1002/hed.23312
https://doi.org/10.1002/hed.23312
Autor:
Sarah Elizabeth, Wheeler, Huifang, Shi, Fangchen, Lin, Sumana, Dasari, Joseph, Bednash, Stephen, Thorne, Simon, Watkins, Radhika, Joshi, Sufi Mary, Thomas
Publikováno v:
Headneck. 36(3)
Head and neck squamous cell carcinoma (HNSCC) has had little improvement in mortality rates in decades. A clearer understanding of the HNSCC tumor microenvironment will aid in finding more effective targeted therapies for this disease. Tumor-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42fa829899310e10127287e4fcd633ca
https://pubmed.ncbi.nlm.nih.gov/23728942
https://pubmed.ncbi.nlm.nih.gov/23728942
Autor:
Jeffrey Straub, Bennett Van Houten, Dhruv Kumar, Hemant Chavan, Yelizaveta Shnayder, Wade R. Gutierrez, Douglas A. Girod, Fangchen Lin, Partha Kasturi, George Leef, Sufi M. Thomas, Kiran Kakarala, Ossama Tawfik, Jacob New, Terance T. Tsue, Radhika Joshi, Shary N. Shelton, Vikalp Vishwakarma, Sumana Dasari
Publikováno v:
Cancer Research. 76:B37-B37
Despite aggressive therapies, head and neck squamous cell carcinoma (HNSCC), which affects 50,000 new patients annually in the United States, is associated with less than 50% 5-year survival. HNSCC tumors display increased glycolysis, even in the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de025cf971e8252b563e196343531a8e
https://doi.org/10.1158/1538-7445.tme16-b37
https://doi.org/10.1158/1538-7445.tme16-b37