Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Fangce Wang"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Despite marked advances in the clinical therapies, clinical outcome of most T-cell acute lymphoblastic leukemia (T-ALL) patients remains poor, due to the high risk of relapse, even after complete remission. Previous studies sugges
Externí odkaz:
https://doaj.org/article/a9213b07ab1d4b29b98aedd9e476a061
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therap
Externí odkaz:
https://doaj.org/article/a9e616d19d7a48db819d95f9273773b3
Autor:
Mengmeng Pan, Pingping Yang, Fangce Wang, Xiu Luo, Bing Li, Yi Ding, Huina Lu, Yan Dong, Wenjun Zhang, Bing Xiu, Aibin Liang
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
BackgroundWith the improvement of clinical treatment outcomes in diffuse large B cell lymphoma (DLBCL), the high rate of relapse in DLBCL patients is still an established barrier, as the therapeutic strategy selection based on potential targets remai
Externí odkaz:
https://doaj.org/article/878f8d214dff4a95b18d09ce964c2fe1
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Periostin (POSTN) is a protein secreted by mesenchymal cells. Periostin is upregulated in several cancer types and overexpression is associated with poor prognosis. However, the functional role and molecular underpinnings of periostin in epithelial o
Externí odkaz:
https://doaj.org/article/adbdc964478a42e292e0f02f15e29e31
Autor:
Guangming Wang, Fangce Wang, Jie Ren, Yue Qiu, Wenjun Zhang, Shane Gao, Danjing Yang, Zhigang Wang, Aibin Liang, Zhengliang Gao, Jun Xu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 2, Pp 657-669 (2018)
Background/Aims: Alternative splicing and DNA damage exhibit cross-regulation, with not only DNA damage inducing changes in alternative splicing, but alternative splicing itself possibly modulating the DNA damage response (DDR). Sirt1, a prominent an
Externí odkaz:
https://doaj.org/article/82d8cb572b044156b1434ba5ffbfda03
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Despite marked advances in the clinical therapies, clinical outcome of most T-cell acute lymphoblastic leukemia (T-ALL) patients remains poor, due to the high risk of relapse, even after complete remission. Previous studies suggest that th
Autor:
Wenlei Yu, Wenjun Zhang, Guangming Wang, Jun Xu, Xiaoxue Tian, Lin Dong, Jie Zhou, Aibin Liang, Jinyuan Lu, Zhuoyi Fan, Zheng Li, Fangce Wang
Publikováno v:
Molecular Medicine Reports
Rearrangement of the mixed lineage leukemia (MLL; also known as lysine methyltransferase 2A) gene is a recurrent genomic aberration in acute myeloid leukemia (AML). MLLT3, super elongation complex subunit (AF9) is one of the most common MLL fusion pa
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Background: Leukaemia stem cells (LSCs) are responsible for the initiation, maintenance, and recurrence of acute myeloid leukaemia (AML), an aggressive haematological malignancy associated with drug resistance and relapse. Identifying therapeutic LSC
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Technology in Cancer Research & Treatment
Technology in Cancer Research & Treatment
Periostin (POSTN) is a protein secreted by mesenchymal cells. Periostin is upregulated in several cancer types and overexpression is associated with poor prognosis. However, the functional role and molecular underpinnings of periostin in epithelial o
Autor:
Jian Wang, Yueshuang Xu, Shuo Li, Wenjun Zhang, Huacheng Luo, Jie Zhou, Jun Xu, Qian Lai, Aibin Liang, Guangming Wang, Fangce Wang, Zhuoyi Fan
Publikováno v:
Oncology Reports
Leukemia, a malignant hematological disease, has poor therapeutic outcomes due to chemotherapeutic resistance. Increasing evidence has confirmed that the elevated capacity for DNA damage repair in cancer cells is a major mechanism of acquired chemoth