Zobrazeno 1 - 10
of 56
pro vyhledávání: '"FangLong Wu"'
Publikováno v:
Case Reports in Oncology, Vol 16, Iss 1, Pp 670-675 (2023)
Plunging ranula, a subtype of ranula, commonly presents as a submandibular or submental cystic mass without oral counterpart, and its clinical management remains challenging. Herein, the authors report an extremely rare case of 30-year-old female pat
Externí odkaz:
https://doaj.org/article/6a79145782594ae78fe821d63c083f86
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Oral squamous cell carcinoma (OSCC) escape from the immune system is mediated through several immunosuppressive phenotypes that are critical to the initiation and progression of tumors. As a hallmark of cancer, DNA damage repair is closely r
Externí odkaz:
https://doaj.org/article/8214553dace64b41b62448216bf37e2d
Autor:
Xueke Shi, Jin Yang, Shuzhi Deng, Hongdan Xu, Deyang Wu, Qingxiang Zeng, Shimeng Wang, Tao Hu, Fanglong Wu, Hongmei Zhou
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-39 (2022)
Abstract Transforming growth factor-β (TGF-β) signaling has a paradoxical role in cancer progression, and it acts as a tumor suppressor in the early stages but a tumor promoter in the late stages of cancer. Once cancer cells are generated, TGF-β s
Externí odkaz:
https://doaj.org/article/190c988969a8411c8841a944085e4797
Autor:
Fanglong Wu, Shimeng Wang, Qingxiang Zeng, Junjiang Liu, Jin Yang, Jingtian Mu, Hongdang Xu, Lanyan Wu, Qinghong Gao, Xin He, Ying Liu, Hongmei Zhou
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-10 (2022)
Abstract Cancer-associated fibroblasts (CAFs) are highly heterogeneous and differentiated stromal cells that promote tumor progression via remodeling of extracellular matrix, maintenance of stemness, angiogenesis, and modulation of tumor metabolism.
Externí odkaz:
https://doaj.org/article/c0784580f64f4ae9a336c5beb8535d94
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tumor-associated macrophages (TAMs) play a critical role in supporting tumor growth and metastasis, taming host immunosurveillance, and augmenting therapeutic resistance. As the current treatment paradigms for cancers are generally insufficient to ex
Externí odkaz:
https://doaj.org/article/907134fa9ec14df58d988fd90ad4e1d0
Autor:
Fanglong Wu, Jin Yang, Junjiang Liu, Ye Wang, Jingtian Mu, Qingxiang Zeng, Shuzhi Deng, Hongmei Zhou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-35 (2021)
Abstract To flourish, cancers greatly depend on their surrounding tumor microenvironment (TME), and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and progression because of their versatile roles in extracellular matri
Externí odkaz:
https://doaj.org/article/2eaa011281254c5aa022f2132f41abd8
Autor:
Jin Yang, Xueke Shi, Miao Yang, Jingjing Luo, Qinghong Gao, Xiangjian Wang, Yang Wu, Yuan Tian, Fanglong Wu, Hongmei Zhou
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract As an important component of the tumor microenvironment, cancer-associated fibroblasts (CAFs) secrete energy metabolites to supply energy for tumor progression. Abnormal regulation of long noncoding RNAs (lncRNAs) is thought to contribute to
Externí odkaz:
https://doaj.org/article/ce3e8b6fda01497787c884ec4c8d8759
Autor:
Xueke Shi, Jingjing Luo, Kelsey J. Weigel, Spencer C. Hall, Danfeng Du, Fanglong Wu, Michael C. Rudolph, Hongmei Zhou, Christian D. Young, Xiao-Jing Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cancer-associated fibroblasts (CAFs) have been shown to enhance squamous cell carcinoma (SCC) growth, but it is unclear whether they promote SCC lung metastasis. We generated CAFs from K15.KrasG12D.Smad4–/– mouse SCCs. RNA expression analyses dem
Externí odkaz:
https://doaj.org/article/19de65004c584648918e885d23a14ec2
Publikováno v:
Life, Vol 12, Iss 5, p 757 (2022)
Stroma–cancer cell crosstalk involves a complex signaling network that contributes to tumor progression, including carcinogenesis, angiogenesis, migration, invasion, and therapy resistance in cancers. Exosomes, as extracellular membranous nanovesic
Externí odkaz:
https://doaj.org/article/0d1e254416264ee08baf2c6a87911f98
Publikováno v:
Biomolecules, Vol 12, Iss 3, p 392 (2022)
Tumor-associated macrophages (TAMs) promote tumor proliferation, invasion, angiogenesis, stemness, therapeutic resistance, and immune tolerance in a protein-dependent manner. Therefore, the traditional target paradigms are often insufficient to exter
Externí odkaz:
https://doaj.org/article/6ea77208a18c40849dbb243f0cddf065