Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Fang-gao Smith"'
Autor:
Shu-yang Xiang, Yang Ye, Qian Yang, Hao- ran Xu, Chen-xi Shen, Min-qi Ma, Shao-wu Jin, Hong-xia Mei, Sheng-xing Zheng, Fang-gao Smith, Sheng-wei Jin, Qian Wang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract The uncontrolled inflammatory response caused by a disorder in inflammation resolution is one of the reasons for acute respiratory distress syndrome (ARDS). The macrophage pool markedly expands when inflammatory monocytes, known as recruited
Externí odkaz:
https://doaj.org/article/639cb9e1364a4757bb0a5a282446cc52
Autor:
Fiona Howroyd, Cyril Chacko, Andrew MacDuff, Nandan Gautam, Brian Pouchet, Bill Tunnicliffe, Jonathan Weblin, Fang Gao-Smith, Zubair Ahmed, Niharika A. Duggal, Tonny Veenith
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Ventilator-associated pneumonia (VAP) affects up to 20% of critically ill patients and induces significant antibiotic prescription pressure, accounting for half of all antibiotic use in the ICU. VAP significantly increases hospital length of
Externí odkaz:
https://doaj.org/article/d0fdb12388ab446f900909c09479d49c
Autor:
Bin Xia, Qiangsheng He, Fang Gao Smith, V. Georgios Gkoutos, Krishnarajah Nirantharakumar, Zi Chong Kuo, Danni Wang, Qi Feng, Eddie C. Cheung, Lunzhi Dai, Junjie Huang, Yuanyuan Yu, Wenbo Meng, Xiwen Qin, Jinqiu Yuan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Proton pump inhibitors (PPIs) are commonly used for gastric acid-related disorders, but their safety profile and risk stratification for high-burden diseases need further investigation. Analyzing over 2 million participants from five prospec
Externí odkaz:
https://doaj.org/article/d7b4a54fc4af40e8ba59087f6ff20e42
Autor:
Ye Gao, Fei Cao, Xinyi Tian, Qianping Zhang, Congcong Xu, Bowen Ji, Ye-an Zhang, Linan Du, Jun Han, Li Li, Siyu Zhou, Yuqiang Gong, Binyu Ying, Fang Gao-Smith, Shengwei Jin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116447- (2024)
Sepsis-induced acute respiratory distress syndrome (ARDS) causes significant fatalities worldwide and lacks pharmacological intervention. Alveolar fluid clearance (AFC) plays a pivotal role in the remission of ARDS and is markedly impaired in the pat
Externí odkaz:
https://doaj.org/article/773fed56b1c641848b8cc6bbd999c3c6
Autor:
Ben Shelley, Andreas Goebel, Stephen Grant, Louise Jackson, Hugh Jarrett, Marcus Jepson, Amy Kerr, Nandor Marczin, Rajnikant Mehta, Teresa Melody, Lee Middleton, Babu Naidu, Lajos Szentgyorgyi, Sarah Tearne, Ben Watkins, Matthew Wilson, Andrew Worrall, Joyce Yeung, Fang Gao Smith
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Thoracotomy is considered one of the most painful surgical procedures and can cause debilitating chronic post-surgical pain lasting months or years postoperatively. Aggressive management of acute pain resulting from thoracotomy ma
Externí odkaz:
https://doaj.org/article/ea1dacffad0f4710a3c3a38d7e492459
Autor:
Ya Lv, Deming Chen, Xinyi Tian, Ji Xiao, Congcong Xu, Linan Du, Jiacong Li, Siyu Zhou, Yuxiang Chen, Rong Zhuang, Yuqiang Gong, Binyu Ying, Fang Gao-Smith, Shengwei Jin, Ye Gao
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Acute lung injury (ALI) is a common and serious complication of sepsis with high mortality. Ferroptosis, categorized as programmed cell death, contributes to the development of lung injury. Protectin conjugates in tissue regenerat
Externí odkaz:
https://doaj.org/article/ffb5cc958b694fafa7596832a2464a30
Publikováno v:
BJA Open, Vol 6, Iss , Pp 100202- (2023)
Externí odkaz:
https://doaj.org/article/673c4fa5d4184d2c8658a12f74f1a710
Autor:
Tonny Veenith, Helena Martin, Martin Le Breuilly, Tony Whitehouse, Fang Gao-Smith, Niharika Duggal, Janet M. Lord, Rubina Mian, David Sarphie, Paul Moss
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Neutrophilia and an elevated neutrophil:lymphocyte ratio are both characteristic features of severe COVID-19 infection. However, functional neutrophil responses have been poorly investigated in this setting. We utilised a novel PMA-based sti
Externí odkaz:
https://doaj.org/article/2cd7f35aea034eb6a1e1caa21fcb1c9f
Publikováno v:
BMJ Open, Vol 12, Iss 8 (2022)
Objectives To describe current UK clinical practice around the use of intrathecal diamorphine as analgesia for major elective laparoscopic colorectal surgery.Design Online self-administered survey.Setting Acute public hospitals in the UK (National He
Externí odkaz:
https://doaj.org/article/a2c11ea29d8a4015a1ab43398a0957c9
Autor:
Xin-xu Zhu, Wen-wu Zhang, Cheng-hua Wu, Shun-shun Wang, Fang Gao Smith, Sheng-wei Jin, Pu-hong Zhang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Sepsis, a life-threatening organ dysfunction, is not caused by direct damage of pathogens and their toxins but by the host’s severe immune and metabolic dysfunction caused by the damage when the host confronts infection. Previous views focused on t
Externí odkaz:
https://doaj.org/article/f9e4876436d64d0293e4ffbd811db141