Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1

Autor: Jun-qi Luo, Tao-wei Yang, Jun Wu, Hou-hua Lai, Li-bin Zou, Wen-bin Chen, Xu-min Zhou, Dao-jun Lv, Sheng-ren Cen, Zi-ning Long, Yi-you Mao, Peng-xiang Zheng, Xiao-hong Su, Zhi-yong Xian, Fang-peng Shu, Xiang-ming Mao

Publikováno v: Cell Death and Disease, Vol 14, Iss 8, Pp 1-14 (2023)

Abstract Tumor-derived exosomes and their contents promote cancer metastasis. Phosphoglycerate mutase 1 (PGAM1) is involved in various cancer-related processes. Nevertheless, the underlying mechanism of exosomal PGAM1 in prostate cancer (PCa) metasta

Externí odkaz: https://doaj.org/article/c40cdfb1f8c1429c81f4f0cb00bcf9e3

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis

Autor: Bin Lei, Li-Xia Xie, Shou-Bo Zhang, Bo Wan, Li-Ren Zhong, Xu-Ming Zhou, Xiang-Ming Mao, Fang-Peng Shu

Publikováno v: Asian Journal of Andrology, Vol 22, Iss 5, Pp 493-499 (2020)

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) is a rate-limiting enzyme and plays an important role in purine and pyrimidine nucleotide synthesis. Recent studies report that PRPS2 is involved in male infertility. However, the role of PRPS2 in hyp

Externí odkaz: https://doaj.org/article/1bb15aa922024d45b63545314361b731

HMGB1 Promotes Prostate Cancer Development and Metastasis by Interacting with Brahma-Related Gene 1 and Activating the Akt Signaling Pathway

Autor: Bin Huang, Hai-Bo Zhang, Xian‑Lu Song, Chong Wang, Hong Chen, Dao‑Jun Lv, Shan‑Chao Zhao, Yu-Zhong Yu, Fang‑Peng Shu

Publikováno v: Theranostics

Background and Aim: We have previously shown that high-mobility group box 1 (HMGB1) is an independent biomarker for shortened survival of prostate cancer (PCa) patients. However, the specific role of HMGB1 in tumor development and progression remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f95d357f27fc17e48f2843e4c4007c5
https://doi.org/10.7150/thno.33972

Validation of aspartate aminotransferase to platelet ratio for diagnosis of liver fibrosis and prediction of postoperative prognosis in infants with biliary atresia.

Autor: Yang LY; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Fu J; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Peng XF; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Pang SY; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Gao KK; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Chen ZR; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., He LJ; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Wen Z; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Wang H; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Li L; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Wang FH; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Yu JK; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Xu Y; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Gong ST; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Xia HM; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China., Liu HY; Li-Yuan Yang, Xiao-Fang Peng, Shu-Yin Pang, Kan-Kan Gao, Hai-Ying Liu, Clinical Laboratory, Guangzhou Medical University Affiliated Guangzhou Women and Children's Medical Center, Guangzhou 510120, Guangdong Province, China.

Publikováno v: World journal of gastroenterology [World J Gastroenterol] 2015 May 21; Vol. 21 (19), pp. 5893-900.