Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Fang-Fang Zhuo"'
Autor:
Fang-Fang Zhuo, Xiao-Qing Li, Jun Zhang, Fu-Ming Zhang, Zhao-Hui Song, Yi He, Li Ding, Dan Liu, Peng-Fei Tu, Xiao-Hui Ma, Ke-Wu Zeng
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39874- (2024)
Nonalcoholic steatohepatitis (NASH), a chronic liver disease characterized by the accumulation of fat in the liver, is highly prevalent on a global scale. In this study, we investigated the effects of total glucosides of Picrorhizae Rhizome (TGPR), t
Externí odkaz:
https://doaj.org/article/8ff0c5c1ebb8465ea282dc3d720154f9
Autor:
Zhuo Yang, Xiao‐Wen Zhang, Fang‐Fang Zhuo, Ting‐Ting Liu, Qian‐Wei Luo, Yong‐Zhe Zheng, Ling Li, Heng Yang, Yi‐Chi Zhang, Yan‐Hang Wang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng
Publikováno v:
Advanced Science, Vol 10, Iss 18, Pp n/a-n/a (2023)
Abstract Osteoblasts play an important role in the regulation of bone homeostasis throughout life. Thus, the damage of osteoblasts can lead to serious skeletal diseases, highlighting the urgent need for novel pharmacological targets. This study intro
Externí odkaz:
https://doaj.org/article/af3072ffab864901936da7ce3f47a1f0
Autor:
Ting-Ting Liu, Heng Yang, Fang-Fang Zhuo, Zhuo Yang, Mei-Mei Zhao, Qiang Guo, Yang Liu, Dan Liu, Ke-Wu Zeng, Peng-Fei Tu
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104353- (2022)
Summary: Background: The E2F family of transcription factors play a crucial role in the development of various cancers. However, E2F members lack targetable binding pockets and are typically considered “undruggable”. Unlike canonical small-molecu
Externí odkaz:
https://doaj.org/article/200c0c8187fd4adeb72787f96a47b589
Autor:
Wei Yu, Min Liao, Yang Chen, Rui Xue, Xiao-Meng Shi, Dan Liu, Fang-Fang Zhuo, Hui Tang, Zhi-Yuan Lu, Peng-Fei Tu, Bo Han, Xin Jia, Ke-Wu Zeng
Publikováno v:
Chemical Communications. 59:1022-1025
Ulcerative colitis (UC) is an inflammatory disease of the colon with an unmet need for therapeutic targets. Ethyl gallate (EG) is a natural small molecule for UC treatment, but its cellular target is unknown. By labelling EG with a diazirine photocro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a168e2f7ed89f1843583d7ba591983f
https://doi.org/10.1039/d2cc05440j
https://doi.org/10.1039/d2cc05440j
Autor:
Qian‐Wei Luo, Lu Yao, Ling Li, Zhuo Yang, Mei‐Mei Zhao, Yong‐Zhe Zheng, Fang‐Fang Zhuo, Ting‐Ting Liu, Xiao‐Wen Zhang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany).
Understanding the direct interaction of nanostructures per se with biological systems is important for biomedical applications. However, whether nanostructures regulate biological systems by targeting specific cellular proteins remains largely unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3476b1665b9df5b6e6e900cb8ecb25ad
https://pubmed.ncbi.nlm.nih.gov/36549896
https://pubmed.ncbi.nlm.nih.gov/36549896
Autor:
Qian‐Wei Luo, Lu Yao, Ling Li, Zhuo Yang, Mei‐Mei Zhao, Yong‐Zhe Zheng, Fang‐Fang Zhuo, Ting‐Ting Liu, Xiao‐Wen Zhang, Dan Liu, Peng‐Fei Tu, Ke‐Wu Zeng
Publikováno v:
Small. 19:2370052
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13769c3709f458e2bf744bf23fba1a84
https://doi.org/10.1002/smll.202370052
https://doi.org/10.1002/smll.202370052
Autor:
Fang‐Fang Zhuo, Qiang Guo, Yong‐Zhe Zheng, Ting‐Ting Liu, Zhuo Yang, Qi‐He Xu, Yong Jiang, Dan Liu, Ke‐Wu Zeng, Peng‐Fei Tu
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(13)
Protopanaxadiol (PPD), a main ginseng metabolite, exerts powerful anticancer effects against multiple types of cancer; however, its cellular targets remain elusive. Here, we synthesized a cell-permeable PPD probe via introducing a bifunctional alkyne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a5f2d50fe64399559d272e8f1f2508
https://pubmed.ncbi.nlm.nih.gov/35442561
https://pubmed.ncbi.nlm.nih.gov/35442561
Seven new cytotoxic phenylspirodrimane derivatives from the endophytic fungus Stachybotrys chartarum
Autor:
Hong Zhang, Ming-Hua Yang, Fang-fang Zhuo, Ling-Yi Kong, Xiao-Bing Wang, Yue-Hu Pei, Na Gao, Xiao-Bei Cheng
Publikováno v:
RSC Advances. 9:3520-3531
Seven undescribed phenylspirodrimane derivatives, stachybochartins A–G (1–7), and four known analogues (8–11) were isolated from the endophytic fungus Stachybotrys chartarum obtained from Pinellia ternata. Stachybochartins A–D are four rare C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adf0354a7d5961a75e9f52c1e7469e08
https://doi.org/10.1039/c8ra10195g
https://doi.org/10.1039/c8ra10195g
Publikováno v:
Journal of Cellular Physiology. 234:13191-13208
Osteosarcoma is the most frequent malignant primary bone tumor, and it generally develops a multidrug resistance. Chrysanthemulide A (CA) is a sesquiterpenoid from the herb Chrysanthemum indicum that has demonstrated a great anti-osteosarcoma potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855ac4ddfdd7bf5e551eed7c72868267
https://doi.org/10.1002/jcp.27991
https://doi.org/10.1002/jcp.27991
Autor:
Hong, Zhang, Ming-Hua, Yang, Fang-Fang, Zhuo, Na, Gao, Xiao-Bei, Cheng, Xiao-Bing, Wang, Yue-Hu, Pei, Ling-Yi, Kong
Publikováno v:
RSC advances. 9(7)
Seven undescribed phenylspirodrimane derivatives, stachybochartins A-G (1-7), and four known analogues (8-11) were isolated from the endophytic fungus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::078ed5fbb409f33e4738799a8a8e102b
https://pubmed.ncbi.nlm.nih.gov/35518072
https://pubmed.ncbi.nlm.nih.gov/35518072