Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Fang Rao"'
Autor:
Qing-Rui Wu, Hui Yang, Hui-Dan Zhang, Yong-Jiang Cai, Yan-Xiang Zheng, Heng Fang, Zi-Fan Wang, Su-Juan Kuang, Fang Rao, Huan-Lei Huang, Chun-Yu Deng, Chun-Bo Chen
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Pyroptosis plays a crucial role in sepsis, and the abnormal handling of myocyte calcium (Ca2+) has been associated with cardiomyocyte pyroptosis. Specifically, the inositol 1,4,5-trisphosphate receptor type 2 (IP3R2) is a Ca2+ release channe
Externí odkaz:
https://doaj.org/article/d16c13dc467b4792bdef3654675c5912
Autor:
Yingyu Lai, Jintao He, Xiaoyan Gao, Dewei Peng, Huishan Zhou, Yuwen Xu, Xueshan Luo, Hui Yang, Mengzhen Zhang, Chunyu Deng, Shulin Wu, Yumei Xue, Feng Zhou, Fang Rao
Publikováno v:
PeerJ, Vol 11, p e16545 (2023)
Plasminogen activator inhibitor-1 (PAI-1), a key regulator of the fibrinolytic system, is also intimately involved in the fibrosis. Although PAI-1 may be involved in the occurrence of atrial fibrillation (AF) and thrombosis in the elderly, but whethe
Externí odkaz:
https://doaj.org/article/3e5aad849a554c5ea7abfe4313df8eba
Autor:
Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li, Su-Juan Kuang, Ying-Yu Lai, Fang Rao, Yu-Mei Xue, Ji-Jin Lin, Shuang-Xin Liu, Chun-Bo Chen, Chun-Yu Deng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-15 (2021)
Abstract Mitochondrial dysfunction and impaired Ca2+ handling are involved in the development of diabetic cardiomyopathy (DCM). Dynamic relative protein 1 (Drp1) regulates mitochondrial fission by changing its level of phosphorylation, and the Orai1
Externí odkaz:
https://doaj.org/article/9539d6068d28411a80554bb61795b308
Autor:
Yuan Fang, Qian Li, Xin Li, Guan-Hao Luo, Su-Juan Kuang, Xue-Shan Luo, Qiao-Qiao Li, Hui Yang, Yang Liu, Chun-Yu Deng, Yu-Mei Xue, Shu-Lin Wu, Fang Rao
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Hypertension is a major cardiovascular risk factor for atrial fibrillation (AF) worldwide. However, the role of mechanical stress caused by hypertension on downregulating the L-type calcium current (ICa,L), which is vital for AF occurrence, remains u
Externí odkaz:
https://doaj.org/article/579946f9d698430bb355a0dae7d2b4e3
Autor:
Qiaoqiao Li, Yingyu Lai, Xiaoyan Gao, Xin Li, Chun-Yu Deng, Huiming Guo, Junfei Zhao, Hui Yang, Yuwen Xu, Shulin Wu, Yumei Xue, Fang Rao
Publikováno v:
PeerJ, Vol 9, p e11488 (2021)
Atrial fibrillation is the most common form of cardiac arrhythmia. Atrial fibrosis is a significant feature of atrial fibrillation though its mechanism is not well understood. We searched the Gene Expression Omnibus database to compare mRNA expressio
Externí odkaz:
https://doaj.org/article/2f1e6df3fc9849dca47dc5089fee229f
Autor:
Qiaoqiao Li, Shenghong Lei, Xueshan Luo, Jintao He, Yuan Fang, Hui Yang, Yang Liu, Chun-Yu Deng, Shulin Wu, Yu-Mei Xue, Fang Rao
Publikováno v:
Reviews in Cardiovascular Medicine, Vol 23, Iss 7, p 247 (2022)
Background: Valvular heart disease (VHD) is a major precipitating factor of atrial fibrillation (AF) that contributes to decreased cardiac function, heart failure, and stroke. Stroke induced by VHD combined with atrial fibrillation (AF-VHD) is a much
Externí odkaz:
https://doaj.org/article/af84ca009ab2489d88b67aedfa7743f4
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 33, Iss 1, Pp 1419-1423 (2019)
RNA interference (RNAi) mediated by microRNA (miRNA) is widely utilized to induce apoptosis and further inhibit the proliferation of cancer cells. MiroRNA-34a (miR-34a) is one of the most potent apoptosis inducers by targeting survivin, which is asso
Externí odkaz:
https://doaj.org/article/0e5b14459fa44b59ac6eaa28109318d0
Autor:
Yubi Lin, Jiana Huang, Siqi He, Ruiling Feng, ZhiAn Zhong, Yang Liu, Weitao Ye, Xin Li, Hongtao Liao, Hongwen Fei, Fang Rao, Zhixin Shan, Chunyu Deng, Xianzhang Zhan, Yumei Xue, Hui Liu, Bin Zhang, Kejian Wang, Qianhuan Zhang, Shulin Wu, Xiufang Lin
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Background Sudden cardiac death (SCD) induced by malignant ventricular tachycardia (MVT) among young adults with right ventricular cardiomyopathy/dysplasia (ARVC/D) is a devastating event. Parts of ARVC/D patients have a mutation in genes en
Externí odkaz:
https://doaj.org/article/d858a55600f44d7e9953d1b56c9231ce
Autor:
Chun-Yu Deng, Hui Yang, Su-Juan Kuang, Fang Rao, Yu-Mei Xue, Zhi-Ling Zhou, Xiao-Ying Liu, Zhi-Xin Shan, Xiao-Hong Li, Qiu-Xiong Lin, Shu-Lin Wu, Xi-Yong Yu
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107128 (2014)
5-Hydroxytryptamine (5-HT) is a powerful constrictor of coronary arteries and is considered to be involved in the pathophysiological mechanisms of coronary-artery spasm. However, the mechanism of enhancement of coronary-artery constriction to 5-HT du
Externí odkaz:
https://doaj.org/article/ddeab7088e074ab284867aeed93e00d0
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89654 (2014)
Hypertension is known to be associated with platelet overactivity, but the direct effects of hydrostatic pressure on platelet function remain unclear. The present study sought to investigate whether elevated hydrostatic pressure is responsible for pl
Externí odkaz:
https://doaj.org/article/174b00a7068640a9ab0003bc8761bfa6