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Multiscale imaging of corneal endothelium damage and Rho-kinase inhibitor application in mouse models of acute ocular hypertension.

Autor: Cai Z; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; Currently with Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zhang Y; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; Currently with Program of Polymer and Color Chemistry, Department of Textile Engineering, Chemistry and Science, North Carolina State University, Raleigh, NC 27606, USA., Fang RS; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Brenner B; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Kweon J; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA., Sun C; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA., Goldberg JL; Spencer Center for Vision Research, Byers Eye Institute, Department of Ophthalmology, Stanford University, Palo Alto, CA 94303, USA., Zhang HF; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.

Publikováno v: Biomedical optics express [Biomed Opt Express] 2024 Jan 25; Vol. 15 (2), pp. 1102-1114. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).

ATM inhibition drives metabolic adaptation via induction of macropinocytosis.

Autor: Huang Z; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Chen CW; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Buj R; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Tangudu NK; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Fang RS; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Leon KE; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.; Biomedical Sciences Graduate Program, Penn State College of Medicine, Hershey, PA., Dahl ES; Biomedical Sciences Graduate Program, Penn State College of Medicine, Hershey, PA., Varner EL; Center for Metabolic Disease Research, Department of Cardiovascular Sciences, Temple University, Philadelphia, PA., von Krusenstiern E; Center for Metabolic Disease Research, Department of Cardiovascular Sciences, Temple University, Philadelphia, PA., Cole AR; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA., Snyder NW; Center for Metabolic Disease Research, Department of Cardiovascular Sciences, Temple University, Philadelphia, PA., Aird KM; Department of Pharmacology & Chemical Biology and UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Publikováno v: The Journal of cell biology [J Cell Biol] 2023 Jan 02; Vol. 222 (1). Date of Electronic Publication: 2022 Nov 18.