Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Fang Hui Lim"'
Autor:
Derong Cao, Jianguo Li, Wee Luan Koh, Donald T.H. Tan, Chandra S. Verma, Rui Ting Soh, Shouping Liu, Rajamani Lakshminarayanan, Roger W. Beuerman, Hanxun Zou, Shuimu Lin, Huifen Lin, Fang Hui Lim, Jun-Jie Koh
Publikováno v:
Journal of Medicinal Chemistry. 59:171-193
We recently reported the bioinspired synthesis of a highly potent nonpeptidic xanthone, 2c (AM-0016), with potent antibacterial activity against MRSA. Herein, we report a thorough structure-activity relationship (SAR) analysis of a series of nonpepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f9ed07584e9c499deef437f85920f8
https://doi.org/10.1021/acs.jmedchem.5b01500
https://doi.org/10.1021/acs.jmedchem.5b01500
Autor:
Carey Fang Hui Lim, Rajamani Lakshminarayanan, Mobashar Hussain Urf Turabe Fazil, Madhavi Latha Somaraju Chalasani, Akshay Mamidi, Seow Theng Ong, Jian Hui Low, Navin Kumar Verma, Atish Kizhakeyil, Dermot Kelleher, Graham D. Wright
Publikováno v:
Scientific Reports
Post-transcriptional gene silencing holds great promise in discovery research for addressing intricate biological questions and as therapeutics. While various gene silencing approaches, such as siRNA and CRISPR-Cas9 techniques, are available, these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d811efcd8b8c4f065b797101616afd4
Autor:
Jianguo Li, Sheng-Xiang Qiu, Padmanabhan Saraswathi, Lei Zhou, Chandra S. Verma, Charles Tang, Jun-Jie Koh, Derong Cao, Huifen Lin, Hanxun Zou, Rajamani Lakshminarayanan, Thet Tun Aung, Donald T.H. Tan, Roger W. Beuerman, Hardy S. O. Chan, Shouping Liu, Xiaoping Dai, Ai Ling Tan, Fang Hui Lim
Publikováno v:
Journal of medicinal chemistry. 56(6)
This work describes how to tune the amphiphilic conformation of α-mangostin, a natural compound that contains a hydrophobic xanthone scaffold, to improve its antimicrobial activity and selectivity for Gram-positive bacteria. A series of xanthone der
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595ac3d7ff92834f441e0d431e5db583
https://pubmed.ncbi.nlm.nih.gov/23441632
https://pubmed.ncbi.nlm.nih.gov/23441632
Autor:
Jun-Jie Koh, Hanxun Zou, Shuimu Lin, Huifen Lin, Rui Ting Soh, Fang Hui Lim, Wee Luan Koh, Jianguo Li, Lakshminarayanan, Rajamani, Verma, Chandra, Tan, Donald T. H., Derong Cao, Beuerman, Roger W., Shouping Liu
Publikováno v:
Journal of Medicinal Chemistry; Jan2016, Vol. 59 Issue 1, p171-193, 23p
Autor:
Charles Tang, Padmanabhan Saraswathi, Rajamani Lakshminarayanan, Roger W. Beuerman, Shouping Liu, Xiaoping Dai, Thet Tun Aung, Sheng-Xiang Qiu, Ai Ling Tan, Chandra S. Verma, Jianguo Li, Fang Hui Lim, Donald T.H. Tan, Huifen Lin, Lei Zhou, Hanxun Zou, Derong Cao, Jun-Jie Koh, Hardy S. O. Chan
Publikováno v:
Journal of Medicinal Chemistry. 56:3747-3747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a2a23fcde994a76dcd00a3f3417794
https://doi.org/10.1021/jm400514x
https://doi.org/10.1021/jm400514x