Zobrazeno 1 - 10
of 3 274
pro vyhledávání: '"Fang, Ma"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Compensation and intracellular storage of PD-L1 may compromise the efficacy of antibody drugs targeting the conformational blockade of PD1/PD-L1 on the cell surface. Alternative therapies aiming to reduce the overall cellular abundance of PD
Externí odkaz:
https://doaj.org/article/c3d4f089e01a4601b0ce46ac377717f1
Autor:
Yang-Yang Wang, Li-Ping Zou, Kai-Feng Xu, Wen-Shuai Xu, Meng-Na Zhang, Qian Lu, Xin-Lun Tian, Ling-Yu Pang, Wen He, Qiu-Hong Wang, Yang Gao, Li-Ying Liu, Xiao-Qiao Chen, Shu-Fang Ma, Hui-Min Chen, Shuo Dun, Xiao-Yan Yang, Xiao-Mei Luo, Lu-Lu Huang, Yu-Fen Li
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Sirolimus is increasingly utilized in treating diseases associated with mTOR pathway overactivation. Despite its potential, the lack of evidence regarding its long-term safety across all age groups, particularly in pediatric patie
Externí odkaz:
https://doaj.org/article/59dc89634fa64050afc31decb64d99fe
Autor:
Jing-Tao Zhang, Zhen-Yu Hu, Fang Tang, Yan-Tao Liu, Wei-Long Tan, Xiao-Fang Ma, Yun-Fa Zhang, Guang-Qian Si, Lei Zhang, Mei-Qi Zhang, Cong Peng, Bo-Kang Fu, Li-Qun Fang, Xiao-Ai Zhang, Wei Liu
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Shrews being insectivores, serve as natural reservoirs for a wide array of zoonotic viruses, including the recently discovered Langya henipavirus (LayV) in China in 2018. It is crucial to understand the shrew-associated virome, viral diversi
Externí odkaz:
https://doaj.org/article/e41c448e04f94d99846a7b699cae87ed
Publikováno v:
International Journal of Nursing Sciences, Vol 11, Iss 3, Pp 308-314 (2024)
Objective: This study aimed to explore the determinants influencing training transfer and evaluate how those factors change over time among nurses who graduated from clinical nurse specialist training to provide a theoretical basis for improving the
Externí odkaz:
https://doaj.org/article/a6f395f232cb455bbd56041c4e1abf6b
Autor:
Shi-Ping Na, Mei-Liang Ning, Ji-Fang Ma, Shuang Liang, Yan-Li Wang, Man-Shu Sui, Xiao-Fang Guo, Ying Ji, Hui-Yan Lyu, Xue-Ying Yuan, Yu-Shi Bao
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-7 (2024)
Abstract Background Hypercoagulability emerges as a central pathological feature and clinical complication in nephrotic syndrome. Increased platelet activation and aggregability are closely related to hypercoagulability in nephrotic syndrome. Monocyt
Externí odkaz:
https://doaj.org/article/c33eb98e568f45ba81e4d0b58f32b4d0
Autor:
Christine Bowman, Michael Dolton, Fang Ma, Sravanthi Cheeti, Denison Kuruvilla, Rucha Sane, Nastya Kassir, Yuan Chen
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 4, Pp 660-672 (2024)
Abstract Pralsetinib, a potent and selective inhibitor of oncogenic RET fusion and RET mutant proteins, is a substrate of the drug metabolizing enzyme CYP3A4 and a substrate of the efflux transporter P‐gp based on in vitro data. Therefore, its phar
Externí odkaz:
https://doaj.org/article/53d6ae92cc93495eba3b71ab9438d4b9
Autor:
Xue-Geng Hong, Ying Zhu, Tao Wang, Jin-Jin Chen, Fang Tang, Rui-Ruo Jiang, Xiao-Fang Ma, Qiang Xu, Hao Li, Li-Ping Wang, Yi Sun, Li-Qun Fang, Wei Liu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 7, p e0012291 (2024)
BackgroundUnderstanding and mapping the distribution of sandflies and sandfly-associated pathogens (SAPs) is crucial for guiding the surveillance and control effort. However, their distribution and the related risk burden in China remain poorly under
Externí odkaz:
https://doaj.org/article/5cd359d6a6bd43468710d00c0fd112f6
Autor:
Yue Zeng, Xing-Xiang Pu, Feng-Jiao He, Chun-Hong Hu, Hong Zhu, Yan Huang, Yu-Rong Peng, Ji-An Zou, Jun-Qi Liu, Sheng-Hao Shi, Yue-Fei Liu, Fang Ma, Chao Deng, Zhen-Hua Qiu, Yan-Long Li, Ying-Zhe Zhang, Kun Huang, Xian-Ling Liu, Fang Wu
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110219- (2024)
Summary: The resected pⅢA-N2 non-small-cell lung cancer (NSCLC) patients who could benefit from postoperative radiotherapy (PORT) are not well-defined. The study explored the role of PORT on EGFR mutant and wild-type NSCLC patients. We retrospectiv
Externí odkaz:
https://doaj.org/article/03d88674394a46c8820d374b2403bda9
Publikováno v:
Zhongguo quanke yixue, Vol 27, Iss 05, Pp 557-562 (2024)
Background Atherosclerosis (AS) causes cardiovascular diseases such as myocardial infarction and myocardial fibrosis. Incidence of the population gradually increases with the aging of the global population. The inflammatory response is a key factor i
Externí odkaz:
https://doaj.org/article/e0e2be62f53e4cafb647e69f368e98a8
Autor:
Qi Jin, Fang Ma, Tongtong Liu, Liping Yang, Huimin Mao, Yuyang Wang, Liang Peng, Ping Li, Yongli Zhan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Sirtuins, which are NAD+-dependent class III histone deacetylases, are involved in various biological processes, including DNA damage repair, immune inflammation, oxidative stress, mitochondrial homeostasis, autophagy, and apoptosis. Sirtuin
Externí odkaz:
https://doaj.org/article/dbc4789bbecd4e1893b6b020cce3209b