A Combined Antitumor Strategy Mediated by a New Targeted Nanosystem to Hepatocellular Carcinoma

Autor: Farinha D, Migawa M, Sarmento-Ribeiro A, Faneca H

Publikováno v: International Journal of Nanomedicine, Vol Volume 16, Pp 3385-3405 (2021)

Dina Farinha,1,2 Michael Migawa,3 Ana Sarmento-Ribeiro,1,4,5 Henrique Faneca1,2 1CNC - Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal; 2Institute for Interdisciplinary Research (IIIUC), University of Coimbra,

Externí odkaz: https://doaj.org/article/ea66b1ab7d6f46d4a3a372657a96f7ed

MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer

Autor: Passadouro M, Pedroso de Lima MC, Faneca H

Publikováno v: International Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 3203-3217 (2014)

Marta Passadouro,1,2 Maria C Pedroso de Lima,1,2 Henrique Faneca11Center for Neuroscience and Cell Biology, 2Department of Life Sciences, Faculty of Science and Technology, University of Coimbra, Coimbra, PortugalAbstract: Pancreatic ductal adenocarc

Externí odkaz: https://doaj.org/article/c196b8417c2648cfa351d6e706883f28

Targeted downregulation of MYC mediated by a highly efficient lactobionic acid-based glycoplex to enhance chemosensitivity in human hepatocellular carcinoma cells.

Autor: Santo D; University of Coimbra, Center for Neuroscience and Cell Biology, Coimbra, Portugal; University of Coimbra, Institute for Interdisciplinary Research, Coimbra, Portugal; University of Coimbra, Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, Coimbra, Portugal., Mendonça PV; University of Coimbra, Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, Coimbra, Portugal., Serra AC; University of Coimbra, Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, Coimbra, Portugal., Coelho JFJ; University of Coimbra, Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, Coimbra, Portugal; IPN, Instituto Pedro Nunes, Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Rua Pedro Nunes, 3030-199 Coimbra, Portugal., Faneca H; University of Coimbra, Center for Neuroscience and Cell Biology, Coimbra, Portugal; University of Coimbra, Institute for Interdisciplinary Research, Coimbra, Portugal. Electronic address: henrique@cnc.uc.pt.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2023 Apr 25; Vol. 637, pp. 122865. Date of Electronic Publication: 2023 Mar 20.

Glycopolymers Mediate Suicide Gene Therapy in ASGPR-Expressing Hepatocellular Carcinoma Cells in Tandem with Docetaxel.

Autor: Santo D; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra 3030-789, Portugal., Cordeiro RA; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra 3030-789, Portugal., Mendonça PV; Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, University of Coimbra, Coimbra 3030-790, Portugal., Serra AC; Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, University of Coimbra, Coimbra 3030-790, Portugal., Coelho JFJ; Centre for Mechanical Engineering, Materials and Processes, Department of Chemical Engineering, University of Coimbra, Coimbra 3030-790, Portugal.; Associação para a Inovação e Desenvolvimento Em Ciência e Tecnologia, IPN─Instituto Pedro Nunes, Rua Pedro Nunes, 3030-199 Coimbra, Portugal., Faneca H; Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-504, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, Coimbra 3030-789, Portugal.

Publikováno v: Biomacromolecules [Biomacromolecules] 2023 Mar 13; Vol. 24 (3), pp. 1274-1286. Date of Electronic Publication: 2023 Feb 13.

Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system

Autor: Faneca, H., Cabrita, A.S., Simões, S., Pedroso de Lima, M.C.

Publikováno v: In BBA - Biomembranes 2007 1768(5):1093-1102