Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fandi Sutanto"'
Autor:
Juan LORELL, Kathy IVANA, Joselyn P.W. TANOTO, Michael MICHAEL, Sarah JESCIKA, Nicolaas R.P. GAUTAMA, Olivia TJOA, Keisha ALINA, Arli A. PARIKESIT, Fandi SUTANTO
Publikováno v:
Notulae Scientia Biologicae, Vol 16, Iss 1 (2024)
Paracetamol, a commonly used analgesic and antipyretic medication, is well-known for its ability to relieve pain and reduce temperature. However, there is a constant push to improve its therapeutic efficacy, especially towards increasing its oral bio
Externí odkaz:
https://doaj.org/article/a53d8574dffa4eb789e3594bc9a16aa5
Autor:
Rizky Nurdiansyah, Agus Budiawan Naro Putra, Ainun Nadhifah, Erika Chriscensia, Ulung Khoe Gondo Kusumo, Stephanie Angela Yosiano, Anastasia Beatrix Musung, Sintikhe A Wenas, Steve Makalew, Patricia Lovina, Intani Quarta Lailaty, Fransisca Aurelia Rahmad, Fandi Sutanto, Pietradewi Hartrianti
Publikováno v:
Pharmaceutical Sciences, Vol 29, Iss 4, Pp 448-458 (2023)
Background: The exploration of bryophytes biodiversity in Indonesia due to its abundance and the bioactivity of its phytochemical content, such as alkaloids and polyphenols, has received increased interest. Despite some species proven to possess phar
Externí odkaz:
https://doaj.org/article/0f14361f13f447baa874b2d1caae1fb5
Autor:
Deniz Eris, Pravin Patil, Matthew Groves, M. Sharpe, Meitian Wang, Mojgan Hadian, Rick Oerlemans, Alexander Dömling, Shabnam Shaabani, Fandi Sutanto
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(33), 18231-18239. WILEY-V C H VERLAG GMBH
Angewandte Chemie (International ed. in English), 60(33), 18231-18239. WILEY-V C H VERLAG GMBH
Protein crystallography (PX) is widely used to drive advanced stages of drug optimization or to discover medicinal chemistry starting points by fragment soaking. However, recent progress in PX could allow for a more integrated role into early drug di
Publikováno v:
RSC Medicinal Chemistry
In this review we provide a brief historic overview of covalent inhibitors and summarize recent advances focusing on developments in the last decade. Applications in challenging targets and future perspectives are also discussed.
Covalent inhibi
Covalent inhibi
Autor:
Andreas Heine, Alexander Dömling, Varsha R. Jumde, Markella Konstantinidou, Anna K. H. Hirsch, Gerhard Klebe, Carlos Jamie Camacho, F. Magari, Fandi Sutanto, M. Yagiz Unver, Jörg Haupenthal
Publikováno v:
Chemmedchem
ChemMedChem
International
Germany
ChemMedChem, 15(8), 680-684. WILEY-V C H VERLAG GMBH
ChemMedChem
International
Germany
ChemMedChem, 15(8), 680-684. WILEY-V C H VERLAG GMBH
Pharmacophore searches that include anchors, fragments contributing above average to receptor binding, combined with one‐step syntheses are a powerful approach for the fast discovery of novel bioactive molecules. Here, we are presenting a pipeline
Autor:
Alexander Dömling, Justyna Kalinowska-Tłuścik, Katarzyna Kurpiewska, Santosh Kurhade, Markella Konstantinidou, Fandi Sutanto
Publikováno v:
European Journal of Organic Chemistry. 2019:2029-2034
A 21 membered library of 2-(imidazo[1,5-alpha]pyridine-1-yl)-1,3,4-oxadiazoles is synthesized in an unprecedented short sequence starting from an Ugi tetrazole reaction with a cleavable isocyanide component. The intermediate tetrazole is subjected to
Autor:
Pravin Patil, Alexander Dömling, Tryfon Zarganes-Tzitzikas, Constantinos G. Neochoritis, Shabnam Shaabani, Fandi Sutanto, Ehsan Ghonchepour
Publikováno v:
Science Advances, 7(6):9307. AMER ASSOC ADVANCEMENT SCIENCE
Science Advances
Science Advances
Electrophiles are used in covalent drug discovery and synthesized from electrophilic building blocks diversified by MCRs.
The area of covalent inhibitors is gaining momentum due to recently introduced clinical drugs, but libraries of these compo
The area of covalent inhibitors is gaining momentum due to recently introduced clinical drugs, but libraries of these compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efe5aa192972d01efa34258477df0d0
https://research.rug.nl/en/publications/9713117d-12b9-4e54-843a-15407b38e73b
https://research.rug.nl/en/publications/9713117d-12b9-4e54-843a-15407b38e73b
Autor:
Fandi Sutanto
Drug discovery is the process by which new medications are discovered. It requires an integrated set of disciplines that work together to support the series of necessary activities to identify and validate drug targets, to design or discover the so-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca31dd95e4009832abd01acadfa9a77
https://doi.org/10.33612/diss.133643092
https://doi.org/10.33612/diss.133643092
Autor:
Santosh Kurhade, Markella Konstantinidou, Fandi Sutanto, Katarzyna Kurpiewska, Justyna Kalinowska-Tłuścik, Alexander Dömling
Publikováno v:
European Journal of Organic Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5d11df4a379ac991f99a4aa48e2cd2ea
https://ruj.uj.edu.pl/xmlui/handle/item/84899
https://ruj.uj.edu.pl/xmlui/handle/item/84899