Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Fan-Chi Hsu"'
1
Akademický článek
CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group
Autor: Andrew J. Menssen, Chad A. Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A. Cook, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Collette Fearing, Keely Ghirardelli, Tiffany Hylkema, Katherine Tarlock, Keith R. Loeb, Edward A. Kolb, Todd Cooper, Jessica Pollard, Denise A. Wells, Michael R. Loken, Richard Aplenc, Soheil Meshinchi, Lisa Eidenschink Brodersen
Publikováno v: Haematologica, Vol 999, Iss 1 (2024)
As curative therapies for pediatric AML remain elusive, identifying potential new treatment targets is vital. We assessed the cell surface expression of CD74, also known as the MHC-II invariant chain, by multidimensional flow cytometry in 973 patient
Externí odkaz: https://doaj.org/article/d6be1ca886894ebe8d63c195735d6fd2
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2
Akademický článek
An RNA-Based Vaccine Platform for Use against Mycobacterium tuberculosis
Autor: Sasha E. Larsen, Jesse H. Erasmus, Valerie A. Reese, Tiffany Pecor, Jacob Archer, Amit Kandahar, Fan-Chi Hsu, Katrina Nicholes, Steven G. Reed, Susan L. Baldwin, Rhea N. Coler
Publikováno v: Vaccines, Vol 11, Iss 1, p 130 (2023)
Mycobacterium tuberculosis (M.tb), a bacterial pathogen that causes tuberculosis disease (TB), exerts an extensive burden on global health. The complex nature of M.tb, coupled with different TB disease stages, has made identifying immune correlates o
Externí odkaz: https://doaj.org/article/7e64074b893a4a918f7781d314137d49
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4
Akademický článek
Heterologous Immunization With Defined RNA and Subunit Vaccines Enhances T Cell Responses That Protect Against Leishmania donovani
Autor: Malcolm S. Duthie, Neal Van Hoeven, Zachary MacMillen, Alessandro Picone, Raodoh Mohamath, Jesse Erasmus, Fan-Chi Hsu, Dan T. Stinchcomb, Steven G. Reed
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
The rapid generation of strong T cell responses is highly desirable and viral vectors can have potent CD8+ T cell-inducing activity. Immunity to leishmaniasis requires selective T cell responses, with immunization schemes that raise either CD4 or CD8
Externí odkaz: https://doaj.org/article/bc3991382b6748c69bbe020ab7fd195d
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5
Akademický článek
Improved Immune Responses in Young and Aged Mice with Adjuvanted Vaccines against H1N1 Influenza Infection
Autor: Susan L. Baldwin, Fan-Chi Hsu, Neal Van Hoeven, Emily Gage, Brian Granger, Jeffrey A. Guderian, Sasha E. Larsen, Erica C. Lorenzo, Laura Haynes, Steven G. Reed, Rhea N. Coler
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Elderly people are at high risk for influenza-related morbidity and mortality due to progressive immunosenescence. While toll-like receptor (TLR) agonist containing adjuvants, and other adjuvants, have been shown to enhance influenza vaccine-induced
Externí odkaz: https://doaj.org/article/cd54c7b7862442a1ab8188b770192449
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7
RNA-based vaccine demonstrates prophylactic efficacy against Mycobacterium tuberculosis challenge in a mouse model
Autor: Sasha E. Larsen, Jesse H. Erasmus, Valerie A. Reese, Tiffany Pecor, Jacob Archer, Amit Kandahar, Fan-Chi Hsu, Steven G. Reed, Susan L. Baldwin, Rhea N. Coler
Mycobacterium tuberculosis (Mtb) is an opportunistic bacterial pathogen that causes tuberculosis disease (TB) and exerts an extensive burden on global health. The complex intra- and extracellular nature of this bacterium, coupled with different disea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd603b76492c69d3abf117ef4ec70c28
https://doi.org/10.1101/2022.02.23.481669
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8
Safety and immunogenicity of the adjunct therapeutic vaccine ID93 + GLA-SE in adults who have completed treatment for tuberculosis: a randomised, double-blind, placebo-controlled, phase 2a trial
Autor: Julia Amsterdam, Alessandro Companie, Fajwa Opperman, Justin Shenje, Steven G. Reed, Elma Van Rooyen, Sandra Goliath, Julia Noble, Tom Rolf, Friedrich Thienemann, Ann Swarts, Rhea N. Coler, Amaryl Van Schalkwyk, Linda-Gail Bekker, Sarah Albertson, Alessandro Sette, Erica Smit, Angelique Mouton, Michele Tameris, Zachary K. Sagawa, Lebohang Makhethe, Yolandi Herselman, Aude Frevol, Yolundi Cloete, Simbarashe Mabwe, Nicole Bilek, Angelique Kany Kany Luabeya, Alana Keyser, Cecilia S. Lindestam Arlehamn, Andrew Fiore-Gartland, Tracey A. Day, Asma Toefy, Carolyn Jones, Thomas J. Scriba, Linda van der Merwe, Constance Schreuder, Natasja Botes, Susan Rossouw, Andreas H. Diacon, Humphrey Mulenga, Adam Penn-Nicholson, Devona Hofmeester, Sandra Kruger, Nelita du Plessis, Fan-Chi Hsu, Jill A. Ashman, Julie Vergara, Anna Marie Beckmann, Eunice Sinandile, Andre G. Loxton, Elisabeth Filander, Ashley Veldsman, Andrea Gutschmidt, Marwou de Kock, Leya Hassanally, Hadn Africa, Stuart Kahn, Yiwen Lu, Marcia Steyn, Timothy D. Reid, Gerhard Walzl, Gail Jacobs, Elize van der Riet, Mark Hatherill, Cynthia Ontong, Nambitha Quaqua, H. Geldenhuys
Publikováno v: The Lancet. Respiratory medicine. 9(4)
Summary Background A therapeutic vaccine that prevents recurrent tuberculosis would be a major advance in the development of shorter treatment regimens. We aimed to assess the safety and immunogenicity of the ID93 + GLA-SE vaccine at various doses an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d96a462b60fe3106efce2a93cd09ebd
https://pubmed.ncbi.nlm.nih.gov/34214500
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10
T Cell Adolescence: Maturation Events Beyond Positive Selection
Autor: Fan Chi Hsu, Yan Xing, Kristin A. Hogquist, Virginia Smith Shapiro
Publikováno v: The Journal of Immunology. 195:1351-1357
Single-positive thymocytes that successfully complete positive and negative selection must still undergo one final step, generally termed T cell maturation, before they gain functional competency and enter the long-lived T cell pool. Maturation initi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e63493e844df29ae26be774e71fcbde2
https://doi.org/10.4049/jimmunol.1501050
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