A human pluripotent stem cell-based model of SARS-CoV-2 infection reveals an ACE2-independent inflammatory activation of vascular endothelial cells through TLR4.

Autor: Ma Z; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Li X; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Fan RLY; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Yang KY; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Ng CSH; Department of Surgery, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Lau RWH; Department of Surgery, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Wong RHL; Department of Surgery, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Ng KK; Department of Surgery, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Wang CC; Department of Obstetrics & Gynaecology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., Ye P; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Fu Z; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China., Chin AWH; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Lai MYA; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Huang Y; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China., Tian XY; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China., Poon LLM; School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; HKU-Pasteur Research Pole, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: llmpoon@hku.hk., Lui KO; Department of Chemical Pathology, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China. Electronic address: kathyolui@cuhk.edu.hk.

Publikováno v: Stem cell reports [Stem Cell Reports] 2022 Mar 08; Vol. 17 (3), pp. 538-555. Date of Electronic Publication: 2022 Feb 17.

Mini viral RNAs act as innate immune agonists during influenza virus infection.

Autor: Te Velthuis AJW; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. ajwt6@cam.ac.uk.; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK. ajwt6@cam.ac.uk., Long JC; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Bauer DLV; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Fan RLY; School of Public Health, University of Hong Kong, Pokfulam, Hong Kong SAR, China., Yen HL; School of Public Health, University of Hong Kong, Pokfulam, Hong Kong SAR, China., Sharps J; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Siegers JY; Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands., Killip MJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.; Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK., French H; Division of Virology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Oliva-Martín MJ; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK., Randall RE; Biomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK., de Wit E; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA., van Riel D; Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands., Poon LLM; School of Public Health, University of Hong Kong, Pokfulam, Hong Kong SAR, China., Fodor E; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK. ervin.fodor@path.ox.ac.uk.

Publikováno v: Nature microbiology [Nat Microbiol] 2018 Nov; Vol. 3 (11), pp. 1234-1242. Date of Electronic Publication: 2018 Sep 17.

SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier.

Autor: Stüdle, Chiara¹ (AUTHOR) chiara.stuedle@unibe.ch, Nishihara, Hideaki^1,2 (AUTHOR), Wischnewski, Sven³ (AUTHOR), Kulsvehagen, Laila⁴ (AUTHOR), Perriot, Sylvain⁵ (AUTHOR), Ishikawa, Hiroshi⁶ (AUTHOR), Schroten, Horst⁷ (AUTHOR), Frank, Stephan⁸ (AUTHOR), Deigendesch, Nikolaus⁸ (AUTHOR), Du Pasquier, Renaud^5,9 (AUTHOR), Schirmer, Lucas^3,10,11 (AUTHOR), Pröbstel, Anne-Katrin⁴ (AUTHOR), Engelhardt, Britta¹ (AUTHOR) britta.engelhardt@unibe.ch

Publikováno v: Fluids & Barriers of the CNS. 10/24/2023, Vol. 20 Issue 1, p1-21. 21p.

substitution spectra of coronavirus genomes.

Autor: Forni, Diego¹ (AUTHOR) diego.forni@lanostrafamiglia.it, Cagliani, Rachele¹ (AUTHOR), Pontremoli, Chiara¹ (AUTHOR), Clerici, Mario^2,3 (AUTHOR), Sironi, Manuela¹ (AUTHOR)

Publikováno v: Briefings in Bioinformatics. Jan2022, Vol. 23 Issue 1, p1-12. 12p.

Effect of genome composition and codon bias on infectious bronchitis virus evolution and adaptation to target tissues.

Autor: Franzo, Giovanni¹ (AUTHOR) giovanni.franzo@unipd.it, Tucciarone, Claudia Maria¹ (AUTHOR), Legnardi, Matteo¹ (AUTHOR), Cecchinato, Mattia¹ (AUTHOR)

Publikováno v: BMC Genomics. 4/7/2021, Vol. 22 Issue 1, p1-12. 12p.