Zobrazeno 1 - 10
of 2 329
pro vyhledávání: '"Fan Chung"'
Autor:
Hisham Abubakar-Waziri, David A. Edwards, Deen Bhandu Bhatta, James H. Hull, Matthew Rudd, Peter Small, Kian Fan Chung
Publikováno v:
ERJ Open Research, Vol 10, Iss 5 (2024)
Background Treatment of chronic cough remains a challenge. We hypothesised that inhaled alkaline hypertonic divalent salts (alkaline HDS) might provide relief for refractory chronic cough by laryngeal and tracheal hydration. Methods We conducted an e
Externí odkaz:
https://doaj.org/article/b7b50f86db8c4494b9289d2dc6fb5cf7
Autor:
Ali Versi, Adnan Azim, Fransiskus Xaverius Ivan, Mahmoud I Abdel‐Aziz, Stewart Bates, John Riley, Mohib Uddin, Nazanin Zounemat Kermani, Anke‐H Maitland‐Van Der Zee, Sven‐Eric Dahlen, Ratko Djukanovic, Sanjay H Chotirmall, Peter Howarth, Ian M Adcock, Kian Fan Chung, the U‐BIOPRED study group
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Severe asthma (SA) encompasses several clinical phenotypes with a heterogeneous airway microbiome. We determined the phenotypes associated with a low α‐diversity microbiome. Methods Metagenomic sequencing was performed on sputu
Externí odkaz:
https://doaj.org/article/06c9519010764d73bb039e9096a28326
Autor:
Hyo-In Rhyou, MD, PhD, Hyun-Kyoung Kim, MPH, Woo-Jung Song, MD, PhD, Sang Min Lee, MD, PhD, Sang-Ha Kim, MD, PhD, Jae-Woo Kwon, MD, PhD, Han-Ki Park, MD, PhD, Hye-Kyung Park, MD, PhD, Sang Hoon Kim, MD, PhD, Jeong-Hee Choi, MD, PhD, Sujeong Kim, MD, PhD, So-Young Park, MD, PhD, Sae-Hoon Kim, MD, PhD, Ji-Yong Moon, MD, PhD, Jae-Woo Jung, MD, PhD, Young-Joo Cho, MD, PhD, Chan Sun Park, MD, PhD, Byung Keun Kim, MD, PhD, Joo-Hee Kim, MD, PhD, Min-Suk Yang, MD, PhD, Min-Hye Kim, MD, PhD, Young-Hee Nam, MD, PhD, Taehoon Lee, MD, PhD, Byung-Jae Lee, MD, PhD, Pankaj Bhavsar, PhD, Ian M. Adcock, PhD, Kian Fan Chung, MD, DSc, Tae-Bum Kim, MD, PhD
Publikováno v:
World Allergy Organization Journal, Vol 17, Iss 9, Pp 100957- (2024)
Background: Anti-type 2 (T2) biologic therapies (biologics) improve exacerbation rates, lung function, and asthma-related quality of life (QoL) in patients with severe T2 asthma. However, studies comparing different biologics are lacking. We evaluate
Externí odkaz:
https://doaj.org/article/c3d9ee64e9d1410390ea957c7f385f40
Autor:
Vincent Laiman, Hsiao-Chi Chuang, Yu-Chun Lo, Tzu-Hsuen Yuan, You-Yin Chen, Didik Setyo Heriyanto, Fara Silvia Yuliani, Kian Fan Chung, Jer-Hwa Chang
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background The impact of cigarette smoke (CS) on lung diseases and the role of microbiome dysbiosis in chronic obstructive pulmonary disease (COPD) have been previously reported; however, the relationships remain unclear. Methods Our researc
Externí odkaz:
https://doaj.org/article/d54a658e49094ea09981628df4823039
Autor:
Yueh-Lun Lee, Didik Setyo Heriyanto, Fara Silvia Yuliani, Vincent Laiman, Lina Choridah, Kang-Yun Lee, Jer-Hwa Chang, Kian Fan Chung, Li-Te Chang, Ta-Yuan Chang, Xiao-Yue Chen, Syue-Wei Peng, Kai-Jen Chuang, Hsiao-Chi Chuang
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Chronic Obstructive Pulmonary Disease (COPD) remains a significant public health challenge due to its high morbidity and mortality rates. Emerging research has identified eosinophilic inflammation as a crucial factor in the pathogenesis an
Externí odkaz:
https://doaj.org/article/07ee14a4069340a9ba48e37435da847d
Autor:
Fan Chung
Publikováno v:
Mediators of Inflammation, Vol 10, Iss 2, Pp 51-59 (2001)
Interleukin-10 (IL-10) is a cytokine derived from CD4+ T-helper type 2 (TH2) cells identified as a suppressor of cytokines from T-helper type 1(TH1) cells. Interleukin-12 (IL-12) is produced by B cells, macrophages and dendritic cells, and primarily
Externí odkaz:
https://doaj.org/article/55a1611ad4ba4ca8b0a912d99c70b193
Autor:
Nazanin Zounemat Kermani, Chuan‐Xing Li, Ali Versi, Yusef Badi, Kai Sun, Mahmoud I Abdel‐Aziz, Martina Bonatti, Anke‐Hilse Maitland‐van der Zee, Ratko Djukanovic, Åsa Wheelock, Sven‐Erik Dahlen, Peter Howarth, Yike Guo, Kian Fan Chung, Ian M. Adcock, U‐BIOPRED Project Team
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 7, Pp n/a-n/a (2024)
Abstract Background Clustering approaches using single omics platforms are increasingly used to characterise molecular phenotypes of eosinophilic and neutrophilic asthma. Effective integration of multi‐omics platforms should lead towards greater re
Externí odkaz:
https://doaj.org/article/4594abc44bb74697a360cdab74ef0794
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/8c7749c29ef344cb95a81c910dd4f845
Autor:
Leah Cuthbertson, Ulrike Löber, Jonathan S. Ish-Horowicz, Claire N. McBrien, Colin Churchward, Jeremy C. Parker, Michael T. Olanipekun, Conor Burke, Aisling McGowan, Gwyneth A. Davies, Keir E. Lewis, Julian M. Hopkin, Kian Fan Chung, Orla O’Carroll, John Faul, Joy Creaser-Thomas, Mark Andrews, Robin Ghosal, Stefan Piatek, Saffron A. G. Willis-Owen, Theda U. P. Bartolomaeus, Till Birkner, Sarah Dwyer, Nitin Kumar, Elena M. Turek, A. William Musk, Jennie Hui, Michael Hunter, Alan James, Marc-Emmanuel Dumas, Sarah Filippi, Michael J. Cox, Trevor D. Lawley, Sofia K. Forslund, Miriam F. Moffatt, William. O. C. Cookson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Microbial communities at the airway mucosal barrier are conserved and highly ordered, in likelihood reflecting co-evolution with human host factors. Freed of selection to digest nutrients, the airway microbiome underpins cognate management o
Externí odkaz:
https://doaj.org/article/fa0a86718fb4447f9b20ab7e4ec9f322
Autor:
Chenfei Li, Qi Liu, Qing Chang, Meiqin Xie, Jiali Weng, Xiaohui Wang, Mengnan Li, Jiani Chen, Yan Huang, Xiaohua Yang, Kai Wang, Na Zhang, Kian Fan Chung, Ian M. Adcock, Hai Zhang, Feng Li
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Mitochondrial dysfunction and lung cellular senescence are significant features involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS) stands as the primary contributing factor to COPD.
Externí odkaz:
https://doaj.org/article/122c5b355ba241d9aa58cde9447e6058