Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Fan'en Yuan"'
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
GBM is one of the most malignant tumor in central nervous system. The resistance to temozolomide (TMZ) is inevitable in GBM and the characterization of TMZ resistance seriously hinders clinical treatment. It is worthwhile exploring the underlying mec
Externí odkaz:
https://doaj.org/article/66c4fb2f50364182ae3d182c47a969ce
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Background Ferroptosis is an iron dependent cell death closely associated with p53 signaling pathway and is aberrantly regulated in glioblastoma (GBM), yet the underlying mechanism needs more exploration. Identifying new factors which regula
Externí odkaz:
https://doaj.org/article/5a31640e3b4a41aeaa6873916c920ed5
Autor:
Yang Xu, Qian Sun, Fan’en Yuan, Huimin Dong, Huikai Zhang, Rongxin Geng, Yangzhi Qi, Xiaoxing Xiong, Qianxue Chen, Baohui Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background Inhibition of p38 MAPK signalling leads to glioblastoma multiform (GBM) tumourigenesis. Nevertheless, the molecular mechanism that induces p38 MAPK signalling pathway silencing during GBM genesis has yet to be determined. Identify
Externí odkaz:
https://doaj.org/article/40483b22b6b4404a986eac3a607e9f02
Autor:
Junhui Liu, Lun Gao, Na Zhan, Pengfei Xu, Ji’an Yang, Fan’en Yuan, Yang Xu, Qiang Cai, Rongxin Geng, Qianxue Chen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background Hypoxia, a fundamental characteristic of glioma, is considered to promote tumor malignancy by inducing process of epithelial mesenchymal transition (EMT). Ferritin Light Chain (FTL) is one of the iron metabolism regulators and is
Externí odkaz:
https://doaj.org/article/eeb26749d4db4d36a016e81e74f216fb
Autor:
Liguo Ye, Yang Xu, Ping Hu, Long Wang, Ji’an Yang, Fan’en Yuan, Yixuan Wang, Chunyu Zhang, Daofeng Tian, Qianxue Chen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Background: Lower-grade glioma (LGG) is the most common histology identified in gliomas, a heterogeneous tumor that may develop into high-grade malignant glioma that seriously shortens patient survival time. Recent studies reported that glutamatergic
Externí odkaz:
https://doaj.org/article/4703303319504c7b88ca77ae37199889
Publikováno v:
PeerJ, Vol 7, p e6560 (2019)
Gliomas are a very diverse group of brain tumors that are most commonly primary tumor and difficult to cure in central nervous system. It’s necessary to distinguish low-grade tumors from high-grade tumors by understanding the molecular basis of dif
Externí odkaz:
https://doaj.org/article/31b9814122374150881103bb32e1532f
Autor:
Lun Gao, Junhui Liu, Shenqi Zhang, Yong Li, Yinqiu Tan, Ji’an Yang, Jiayang Cai, Long Wang, Fan’en Yuan, Zhang Ye, Shi’ao Tong, Baohui Liu, Daofeng Tian, Gang Deng, Qianxue Chen
Background Gliomas are the most common malignant tumors of the central nervous system in adults, glioblastoma is notorious for its highly metastatic and recurrent, accounting for approximately 50% of all gliomas. Exploring its molecular mechanism is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4030d4a347f2ab86ea05600d04ca7167
https://doi.org/10.21203/rs.3.rs-1403508/v2
https://doi.org/10.21203/rs.3.rs-1403508/v2
Autor:
Yixuan Wang, Yuntao Li, Qian Sun, Fan'en Yuan, Yang Xu, Shiao Tong, Yong Li, Shangfeng Yi, Tengfeng Yan, Qianxue Chen, Baohui Liu
Publikováno v:
Experimental cell research. 417(2)
As in many other cancers, highly malignant proliferation and disordered cell division play irreplaceable roles in the exceedingly easy recurrence and complex progression of glioblastoma multiforme (GBM); however, mechanistic studies of the numerous r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb4e2fc4c449dce87511030c3330331
https://pubmed.ncbi.nlm.nih.gov/35659972
https://pubmed.ncbi.nlm.nih.gov/35659972
Autor:
Yixuan Wang, Si Zhang, Qian Sun, Fan’en Yuan, Linyao Zhao, Zhang Ye, Yong Li, Ronggui Wang, Hongxiang Jiang, Ping Hu, Daofeng Tian, Baohui Liu
WAC is closely related to the occurrence and development of tumors. However, its role in human glioblastoma (GBM) and its potential regulatory mechanisms have not been investigated. This study demonstrated that WAC is downregulated in GBM, and its lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69e5d4a1e53860a6112562ee92408926
https://doi.org/10.21203/rs.3.rs-771107/v1
https://doi.org/10.21203/rs.3.rs-771107/v1
Autor:
Yang Xu, Qian Sun, Fan’en Yuan, Huimin Dong, Huikai Zhang, Rongxin Geng, Yangzhi Qi, Xiaoxing Xiong, Baohui Liu, Qianxue Chen
Background Inhibition of p38 MAPK signaling leads to glioblastoma multiform (GBM) tumorigenesis. Nevertheless, the molecular mechanism which induces the p38 MAPK signaling silent during GBM genesis is yet to be figured out. Identifying new factors wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7965fa9b6dd1710c3f0a805bd2dd7b0
https://doi.org/10.21203/rs.3.rs-27044/v1
https://doi.org/10.21203/rs.3.rs-27044/v1