Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Familial Neuroblastoma"'
Autor:
Hongyan Zhang, Takehiko Kamijo, Junichi Ueyama, Zhibo Gao, Yuanyuan Li, Miki Ohira, Yohko Nakamura, Huanming Yang, Tatsuro Tajiri, Ye Yin, Teng Xiong, Rui Zhou, Jian Wang, Yasuhiko Kaneko, and Akira Nakagawara, Chao Yang, Takeshi Taketani, Yong Zhou, Xiangchun Li, Wen Luo
Publikováno v:
Oncotarget
Neuroblastoma (NB) is a childhood solid malignant tumor originating from precursor cells of the peripheral nervous system. We have previously established a risk classification system based on DNA copy number profiles. To further explore the pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97df26f535c3dc7d977a911840419c45
https://doi.org/10.18632/oncotarget.18079
https://doi.org/10.18632/oncotarget.18079
Publikováno v:
Atlas Genet Cytogenet Oncol Haematol
Neuroblastoma is a clinically heterogenous pediatric cancer of the sympathetic nervous system that originates from neural crest cells. It is the most common extracranial solid tumor in childhood and prognosis ranges from spontaneous tumor regression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e626eebd0aa1fc4e54bed04b5ca4b2
https://doi.org/10.4267/2042/70771
https://doi.org/10.4267/2042/70771
Autor:
Takuya Kamio, Kenichi Yoshida, Tomohiko Sato, Ko Kudo, Tsutomu Toki, Etsuro Ito, Kaori Kubo, Yusuke Shiozawa, Shinya Sasaki, Seishi Ogawa, Kiminori Terui, Rika Kanezaki, Akie Kobayashi, Akira Kurose, Hiroo Ueno
Publikováno v:
Genes, Chromosomes and Cancer. 57:665-669
The authors report two siblings with familial neuroblastoma with a germline R1275Q mutation of the tyrosine kinase domain of ALK. Whole exome sequencing and copy number variation assay were performed to investigate genetic alterations in the two case
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802eeea8e6c1478d744405af7dd8bf62
https://doi.org/10.1002/gcc.22676
https://doi.org/10.1002/gcc.22676
Akademický článek
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Publikováno v:
Pediatric Hematology and Oncology. 34:165-185
Neuroblastoma is the most common extracranial solid tumor in childhood accounting for 8-10% of all childhood malignancies. The tumor is characterized by a spectrum of histopathologic features and a heterogeneous clinical phenotype. Modern multimodali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92bffd622c42676960cf0f24cc9bd9a
https://doi.org/10.1080/08880018.2017.1330375
https://doi.org/10.1080/08880018.2017.1330375
Publikováno v:
Current Opinion in Genetics & Development. 42:81-90
Until recently, the genetic basis of neuroblastoma, a heterogeneous neoplasm arising from the developing sympathetic nervous system, remained undefined. The discovery of gain-of-function mutations in the ALK receptor tyrosine kinase gene as the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ba4bd003fda596a7db183463ae1630
https://doi.org/10.1016/j.gde.2017.03.008
https://doi.org/10.1016/j.gde.2017.03.008
Autor:
Daniel A. Weiser, Damon R. Reed, Bradley Rybinski, Andrew S. Brohl, Tamar Wolinsky, Scott Moerdler, Michelle Ewart
Publikováno v:
Genes, chromosomescancerREFERENCES. 59(2)
Neuroblastoma, the most common extracranial solid tumor of childhood, can present in multiple primary sites, but the extent of genetic heterogeneity among tumor foci, as well as the presence or absence of common oncogenic drivers, remains unknown. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7d7d51621a74cf9a6fd5c21eaf4ede
https://pubmed.ncbi.nlm.nih.gov/31515834
https://pubmed.ncbi.nlm.nih.gov/31515834
Autor:
Erin K. Barr, Mark A. Applebaum
Publikováno v:
Children
Children, Vol 5, Iss 9, p 119 (2018)
Children, Vol 5, Iss 9, p 119 (2018)
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis. While neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90ea07ef8a6227c404f4613b57d5edb
https://pubmed.ncbi.nlm.nih.gov/30200332
https://pubmed.ncbi.nlm.nih.gov/30200332
Autor:
Yu Shi, Yi Deng, Lars Rönnstrand, Bo Feng, Wai-Yee Chan, Jianmin Sun, Hui Zhao, Yonglong Chen, Ruijun Tian, Lin Zou, Sun-On Chan, Julhash U. Kazi, Tianfeng Li
Publikováno v:
Oncogene. 37(47)
Aberrant activation of anaplastic lymphoma kinase (ALK) can cause sporadic and familial neuroblastoma. Using a proteomics approach, we identified Bruton’s tyrosine kinase (BTK) as a novel ALK interaction partner, and the physical interaction was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed19eaa7c8339eb1dd663ab2809aeb8
https://pubmed.ncbi.nlm.nih.gov/30013190
https://pubmed.ncbi.nlm.nih.gov/30013190
Publikováno v:
Cell and tissue research. 372(2)
Neuroblastoma, a malignancy of the developing peripheral nervous system that affects infants and young children, is a complex genetic disease. Over the past two decades, significant progress has been made toward understanding the genetic determinants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5406b6abf69006a23c8407cd9be0018c
https://pubmed.ncbi.nlm.nih.gov/32897422
https://pubmed.ncbi.nlm.nih.gov/32897422