Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Falu Wang"'
Autor:
Chong Huang, Huiping Shuai, Jingxin Qiao, Yuxin Hou, Rui Zeng, Anjie Xia, Lingwan Xie, Zhen Fang, Yueyue Li, Chaemin Yoon, Qiao Huang, Bingjie Hu, Jing You, Baoxue Quan, Xiu Zhao, Nihong Guo, Shiyu Zhang, Ronggang Ma, Jiahao Zhang, Yifei Wang, Ruicheng Yang, Shanshan Zhang, Jinshan Nan, Haixing Xu, Falu Wang, Jian Lei, Hin Chu, Shengyong Yang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Emerging SARS-CoV-2 variants, particularly the Omicron variant and its sublineages, continually threaten the global public health. Small molecule antivirals are an effective treatment strategy to fight against the virus. However, the first-g
Externí odkaz:
https://doaj.org/article/e367941cf8254edc941c968025198a75
Autor:
Yueshan Li, Liting Zhang, Yifei Wang, Jun Zou, Ruicheng Yang, Xinling Luo, Chengyong Wu, Wei Yang, Chenyu Tian, Haixing Xu, Falu Wang, Xin Yang, Linli Li, Shengyong Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Retrieval of a new starting active compound with a novel scaffold during early drug development is an important but challenging task. Here, the authors propose a generative deep learning model and by applying this model they discover a potent and hig
Externí odkaz:
https://doaj.org/article/75a88dd4da1d4bd8a674229c98de8eec
Publikováno v:
Catalysts, Vol 12, Iss 3, p 348 (2022)
Nitrate (NO3−) reduction in water has been receiving increasing attention in water treatment due to its carcinogenic and endocrine-disrupting properties. This study employs a novel advanced reduction process, the UV/oxalic acid/ferric iron systems
Externí odkaz:
https://doaj.org/article/ff3efe442d50420c8db41af97646513e
Autor:
Shengyong Yang, Hailin Zhang, Yueshan Li, Falu Wang, Guifeng Lin, Ting Niu, He Li, Yuyao Yi, Hui Zhou, Ruicheng Yang, Rui Yao, Pei Zhou, Yueyue Li, Mengdan Wu, Ming-Xin Chen, Haixing Xu, Jing You, Yi Liao, Chenlu Yang, Ailin Zhao, Chong Chen, Linli Li, Yuquan Wei
N6-methyladenosine (m6A) is the most prevalent modification of eukaryotic RNA, which is recognized by m6A-binding proteins (“readers”) and thereby mediates multiple biological processes. Dysregulation of the m6A readers has been linked to various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a693655517bc10d905a2ee0d0571dd10
https://doi.org/10.21203/rs.3.rs-2644364/v1
https://doi.org/10.21203/rs.3.rs-2644364/v1
Autor:
Shulei Pan, Liting Zhang, Xinling Luo, Jinshan Nan, Wei Yang, Huachao Bin, Yang Li, Qiao Huang, Tianqi Wang, Zhiling Pan, Bo Mu, Falu Wang, Chenyu Tian, Yang Liu, Linli Li, Shengyong Yang
Publikováno v:
Journal of Medicinal Chemistry. 65:2035-2058
Autor:
Yan Jiao, Jinshan Nan, Bo Mu, Yun Zhang, Nenghua Zhou, Shunhua Yang, Shanshan Zhang, Wanting Lin, Falu Wang, Anjie Xia, Zhixing Cao, Pei Chen, Zhiling Pan, Guifeng Lin, Shulei Pan, Huachao Bin, Linli Li, Shengyong Yang
Publikováno v:
European journal of medicinal chemistry. 232
The NLRP3 inflammasome, which regulated a proinflammatory programmed cell death form termed pyroptosis, is involved in the pathological process of various human diseases, such as multiple sclerosis, type 2 diabetes, and gout. Thus, compounds inhibiti
Autor:
Fei Xue, Huan He, Dan Zhang, Xiao-Yu Liu, Min Zhu, Liping He, Falu Wang, Jiamei Di, Jiazhen Liu, Huifang Lu, Qi Liao, Yong Qin, Hao Song
Publikováno v:
Angewandte Chemie. 130:6777-6781
Herein, we present a new desulfurative method for generating primary, secondary, and tertiary alkyl radicals through visible-light photoredox catalysis. A process that involves the generation of N-centered radicals from sulfinamide intermediates, fol
Publikováno v:
Angewandte Chemie. 129:3757-3761
The asymmetric total syntheses of a group of structurally complex Kopsia alkaloids, (-)-kopsine, (-)-isokopsine, (+)-methyl chanofruticosinate, (-)-fruticosine, and (-)-kopsanone, has been achieved. The key strategies for the construction of the mole
Publikováno v:
Chemical communications (Cambridge, England). 54(37)
A photoredox-mediated, regiospecific alkyl addition reaction of (hetero)arene-fused thiophenes has been developed, employing bench-stable N-benzoyl alkyl-sulfinamides as the alkyl sources. This protocol offers a unique desulfuration approach to gener
Publikováno v:
European Journal of Organic Chemistry. 2015:5755-5763
A practical, recyclable strategy for homogeneous cinchona alkaloid-derived primary amine organocatalysts was developed by controlling the solubilities in an aqueous/organic biphasic system through regulating the pH of the aqueous phase, effecting the