Zobrazeno 1 - 2
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pro vyhledávání: '"Falong Jiang"'
Autor:
Yanjin Zhao, Pengyu Qian, Yanyang Li, Yan Zhou, Wenxiang Hu, Falong Jiang, Zhenglin Yao, Yongzhen Wang, Shuxin Li
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:179-182
A series of novel benzamides derivatives was designed and synthesized as HDAC inhibitors. Exploration of the structure–activity relationships resulted in compounds that are potent in vitro. In addition, the best compound 1a exhibited an acceptable
Autor:
Falong Jiang, Weiping Huang, Yanyang Li, Shan Yao, Yanjin Zhao, Zhenglin Yao, Shoujun Yuan, Shanyou Yu, Wenhu Zhan, Shuxin Li
Publikováno v:
Bioorganicmedicinal chemistry. 20(14)
A series of novel bis-aryl ureas containing trifluoromethyl imidazolyl group targeting Raf kinase were designed and synthesized based on the lead compound of Sorafenib. All the prepared compounds were evaluated for their in vitro antiproliferative ac