Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Fallon K Noto"'
The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies.
Autor:
Fallon K Noto, Jaya Sangodkar, Bisoye Towobola Adedeji, Sam Moody, Christopher B McClain, Ming Tong, Eric Ostertag, Jack Crawford, Xiaohua Gao, Lauren Hurst, Caitlin M O'Connor, Erika N Hanson, Sudeh Izadmehr, Rita Tohmé, Jyothsna Narla, Kristin LeSueur, Kajari Bhattacharya, Amit Rupani, Marwan K Tayeh, Jeffrey W Innis, Matthew D Galsky, B Mark Evers, Analisa DiFeo, Goutham Narla, Tseten Y Jamling
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240169 (2020)
We have created the immunodeficient SRG rat, a Sprague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. This model has been tested and validated for use in oncology (SRG OncoRat®). The SRG rat demonstra
Externí odkaz:
https://doaj.org/article/da40f8be4ff04612b39481863ba9aa2b
Autor:
Tseten Y. Jamling, Goutham Narla, Jack Crawford, Analisa DiFeo, Jaya Sangodkar, Sahar Mazhar, Eric Ostertag, Christopher B. McClain, Angela Arey, Wei Zhang, Kameswaran Ravichandran, Min Tong, Valeriya Adjan-Steffey, Fallon K. Noto
Karyotype analysis for Spermatogonia at passage 16, before transfection with XTNs demonstrating a normal male 40, XY karyotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6394b141c38455f1e52a674ebf544168
https://doi.org/10.1158/1535-7163.22505298
https://doi.org/10.1158/1535-7163.22505298
Autor:
Tseten Y. Jamling, Goutham Narla, Jack Crawford, Analisa DiFeo, Jaya Sangodkar, Sahar Mazhar, Eric Ostertag, Christopher B. McClain, Angela Arey, Wei Zhang, Kameswaran Ravichandran, Min Tong, Valeriya Adjan-Steffey, Fallon K. Noto
ANOVA with multiple comparisons and Tukey's post-hoc test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e76b6d33e007c079b8badbbf28e131
https://doi.org/10.1158/1535-7163.22505289.v1
https://doi.org/10.1158/1535-7163.22505289.v1
Autor:
Goutham Narla, Analisa DiFeo, Dmitriy Zamarin, Jaya Sangodkar, Arathi Mohan, Jonida Trako, Fallon K. Noto, Kaitlin P. Zawacki, Tahra K. Suhan, Terrance J. Haanen, Lauren Hurst, Kathryn M. Miller, Sarah E. Taylor, Caitlin M. O'Connor
Uterine serous carcinoma (USC) is a highly aggressive endometrial cancer subtype with limited therapeutic options and a lack of targeted therapies. While mutations to PPP2R1A, which encodes the predominant protein phosphatase 2A (PP2A) scaffolding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e66eae25800a45b3be62d43955be573
https://doi.org/10.1158/0008-5472.c.6513828
https://doi.org/10.1158/0008-5472.c.6513828
Autor:
Goutham Narla, Analisa DiFeo, Dmitriy Zamarin, Jaya Sangodkar, Arathi Mohan, Jonida Trako, Fallon K. Noto, Kaitlin P. Zawacki, Tahra K. Suhan, Terrance J. Haanen, Lauren Hurst, Kathryn M. Miller, Sarah E. Taylor, Caitlin M. O'Connor
Supplementary Figure from Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b87f1e80781e0f55b7309eb67d934d9
https://doi.org/10.1158/0008-5472.22431174
https://doi.org/10.1158/0008-5472.22431174
Autor:
Goutham Narla, Analisa DiFeo, Dmitriy Zamarin, Jaya Sangodkar, Arathi Mohan, Jonida Trako, Fallon K. Noto, Kaitlin P. Zawacki, Tahra K. Suhan, Terrance J. Haanen, Lauren Hurst, Kathryn M. Miller, Sarah E. Taylor, Caitlin M. O'Connor
Supplementary Data from Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec0520d44cfb927dfbd445f5b915589
https://doi.org/10.1158/0008-5472.22431177.v1
https://doi.org/10.1158/0008-5472.22431177.v1
Autor:
R. Grace Walton, Diane Begemann, Cynthia Dunn, Valeria Steffey, Abigail Ross, Razoanul Haque, Fallon K. Noto
Publikováno v:
Molecular Cancer Research. 21:A040-A040
RAS family proteins are important drug targets in multiple cancers due to their central role in hypertrophic and pro-mitotic signaling. KRAS is a small GTPase that is activated in response to growth factors including HGF, TGFα, and EGF. KRAS then ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b85c6e16d9102400c8eff15c0e3435b
https://doi.org/10.1158/1557-3125.ras23-a040
https://doi.org/10.1158/1557-3125.ras23-a040
Autor:
Diane Begemann, Aida Javidan, Cynthia Dunn, Nicolas Johnston, R. Grace Walton, Valeriya Steffey, Ian Corbin, Niveen Fulcher, Cleusa De Oliveira, Hu Xu, Mila Uzelac, Andrew Deweyert, John A. Ronald, Susanne Schmid, Matthew O. Hebb, Fallon K. Noto
Publikováno v:
Cancer Research. 83:42-42
Human cancer xenografts are a vital tool for understanding tumor biology, growth kinetics, and therapeutic efficacy using animal models. Historically, immunodeficient mice have been the standard rodent species for cancer xenograft modeling. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e584b811f6245422bd42df90d3f7ba6
https://doi.org/10.1158/1538-7445.am2023-42
https://doi.org/10.1158/1538-7445.am2023-42
Autor:
Caitlin M. O'Connor, Sarah E. Taylor, Kathryn M. Miller, Lauren Hurst, Terrance J. Haanen, Tahra K. Suhan, Kaitlin P. Zawacki, Fallon K. Noto, Jonida Trako, Arathi Mohan, Jaya Sangodkar, Dmitriy Zamarin, Analisa DiFeo, Goutham Narla
Publikováno v:
Cancer Res
Uterine serous carcinoma (USC) is a highly aggressive endometrial cancer subtype with limited therapeutic options and a lack of targeted therapies. While mutations to PPP2R1A, which encodes the predominant protein phosphatase 2A (PP2A) scaffolding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecef52056c7de536db02e4e1136d030a
https://pubmed.ncbi.nlm.nih.gov/34921012
https://pubmed.ncbi.nlm.nih.gov/34921012
Autor:
Caitlin M. O'Connor, Sarah E. Taylor, Kathryn M. Miller, Lauren Hurst, Terrance J. Haanen, Tahra K. Suhan, Kaitlin P. Zawacki, Fallon K. Noto, Jonida Trako, Arathi Mohan, Jaya Sangodkar, Dmitriy Zamarin, Analisa DiFeo, Goutham Narla
Publikováno v:
Cancer Research. 82:3341-3341
Uterine serous carcinoma (USC) is a highly aggressive endometrial cancer subtype with limited therapeutic options and a lack of targeted therapies. While mutations to PPP2R1A, encoding the predominant protein phosphatase 2A (PP2A) scaffolding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04093cea95c0b5ab7f6567eccd9e94d3
https://doi.org/10.1158/1538-7445.am2022-3341
https://doi.org/10.1158/1538-7445.am2022-3341