Pentacyclic triterpenes modulate farnesoid X receptor expression in colonic epithelial cells: Implications for colonic secretory function.

Autor: Fallon CM; The School of Pharmacy and Biomolecular Sciences, RCSI, Beaumont Hospital, Dublin, Ireland. Electronic address: cfallon@rcsi.com., Smyth JS; The School of Pharmacy and Biomolecular Sciences, RCSI, Beaumont Hospital, Dublin, Ireland., Quach A; Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA., Lajczak-McGinley N; The School of Pharmacy and Biomolecular Sciences, RCSI, Beaumont Hospital, Dublin, Ireland., O'Toole A; Department of Gastroenterology, Beaumont Hospital, Dublin, Ireland., Barrett KE; Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA; Department of Physiology and Membrane Biology, School of Medicine, University of California Davis, Davis, California, USA., Sheridan H; NatPro, Centre for Natural Product Research, School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland., Keely SJ; The School of Pharmacy and Biomolecular Sciences, RCSI, Beaumont Hospital, Dublin, Ireland.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Nov; Vol. 298 (11), pp. 102569. Date of Electronic Publication: 2022 Oct 06.

The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis.

Autor: Lajczak-McGinley NK; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland., Porru E; Department of Chemistry, University of Bologna, Bologna, Italy., Fallon CM; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland., Smyth J; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland., Curley C; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland., McCarron PA; School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland., Tambuwala MM; School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland., Roda A; Department of Chemistry, University of Bologna, Bologna, Italy.; INBB, National Institute of Bio structures and Biosystems, Rome, Italy., Keely SJ; Department of Molecular Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.

Publikováno v: Physiological reports [Physiol Rep] 2020 Jun; Vol. 8 (12), pp. e14456.

Metaschoepite Dissolution in Sediment Column Systems-Implications for Uranium Speciation and Transport.

Autor: Bower WR; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL.; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL.; Radiochemistry Unit, Department of Chemistry , The University of Helsinki , Helsinki , Finland , 00014., Morris K; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL., Livens FR; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL.; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL., Mosselmans JFW; Diamond Light Source , Harwell Science and Innovation Campus , Didcot , U.K. , OX11 0DE., Fallon CM; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL.; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL.; Radiochemistry Unit, Department of Chemistry , The University of Helsinki , Helsinki , Finland , 00014., Fuller AJ; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL., Natrajan L; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL., Boothman C; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL., Lloyd JR; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL., Utsunomiya S; Kyushu University , Department of Chemistry , 744 Motooka , Nishi-ku , Fukuoka Japan , 819-0395., Grolimund D; Swiss Light Source , Paul Scherrer Institute , Villigen , Switzerland , 5232., Ferreira Sanchez D; Swiss Light Source , Paul Scherrer Institute , Villigen , Switzerland , 5232., Jilbert T; Ecosystems and Environmental Research Programme, Faculty of Biological and Environmental Sciences , The University of Helsinki , Helsinki , Finland , 00014., Parker J; Diamond Light Source , Harwell Science and Innovation Campus , Didcot , U.K. , OX11 0DE., Neill TS; Research Centre for Radwaste Disposal and Williamson Research Centre, School of Earth and Environmental Sciences , The University of Manchester , Manchester , U.K. , M13 9PL., Law GTW; Centre for Radiochemistry Research, School of Chemistry , The University of Manchester , Manchester , U.K. , M13 9PL.; Radiochemistry Unit, Department of Chemistry , The University of Helsinki , Helsinki , Finland , 00014.

Publikováno v: Environmental science & technology [Environ Sci Technol] 2019 Aug 20; Vol. 53 (16), pp. 9915-9925. Date of Electronic Publication: 2019 Aug 01.

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.

Autor: Ní Cheallaigh C; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland. Electronic address: nicheacm@tcd.ie., Sheedy FJ; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Harris J; Centre for Inflammatory Diseases, Southern Clinical School, Monash University Faculty of Medicine, Nursing and Health Sciences, Clayton, Victoria 3168, Australia., Muñoz-Wolf N; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Lee J; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., West K; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., McDermott EP; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Smyth A; UCD Schools of Veterinary Medicine, Medicine and Medical Science, and Biomolecular and Biomedical Science, and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland., Gleeson LE; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Coleman M; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Martinez N; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Hearnden CH; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Tynan GA; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Carroll EC; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Jones SA; Centre for Inflammatory Diseases, Southern Clinical School, Monash University Faculty of Medicine, Nursing and Health Sciences, Clayton, Victoria 3168, Australia., Corr SC; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Bernard NJ; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Hughes MM; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Corcoran SE; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., O'Sullivan M; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Fallon CM; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland., Kornfeld H; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Golenbock D; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA., Gordon SV; UCD Schools of Veterinary Medicine, Medicine and Medical Science, and Biomolecular and Biomedical Science, and UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland., O'Neill LA; Inflammation Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland., Lavelle EC; Adjuvant Research Group, School of Biochemistry & Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, D02 PN40, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College, D02 PN40, Dublin, Ireland. Electronic address: lavellee@tcd.ie., Keane J; Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin and St. James's Hospital, D08 W9RT, Dublin, Ireland.

Publikováno v: Immunity [Immunity] 2016 Feb 16; Vol. 44 (2), pp. 368-79.

Molecular clocks for isotopic analysis.

Autor: Mao, Xianglei¹ (AUTHOR) x_mao@lbl.gov, Chirinos, Jose¹ (AUTHOR), Zorba, Vassilia^1,2 (AUTHOR) vzorba@lbl.gov

Publikováno v: Applied Physics A: Materials Science & Processing. May2023, Vol. 129 Issue 5, p1-11. 11p. 1 Diagram, 1 Chart, 8 Graphs.